Molecular hydrogen: an overview of its neurobiological effects and therapeutic potential for bipolar disorder and schizophrenia.
Ahmad Ghanizadeh, Michael Berk · Medical gas research · 2013
Research-use notice
Independent study record
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H2HUBB TAKEAWAY
Specifically, both bipolar disorder and schizophrenia are associated with increased oxidative and inflammatory stress. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
How Molecular Hydrogen Was Addressed
It is hypothesized that administration of hydrogen molecule may have potential as a novel therapy for bipolar disorder, schizophrenia, and other concurrent disorders characterized by oxidative, inflammatory and apoptotic dysregulation.
What the Publication Reported
Specifically, both bipolar disorder and schizophrenia are associated with increased oxidative and inflammatory stress.
H₂ Mechanisms / Biological Findings
Hydrogen gas is a bioactive molecule that has a diversity of effects, including anti-apoptotic, anti-inflammatory and anti-oxidative properties; these overlap with the process of neuroprogression in major psychiatric disorders. it is hypothesized that administration of hydrogen molecule may have potential as a novel therapy for bipolar disorder, schizophrenia, and other concurrent disorders characterized by oxidative, inflammatory and apoptotic dysregulation.