Molecular hydrogen in the treatment of acute and chronic neurological conditions: mechanisms of protection and routes of administration.
Kenji Dohi, Kazue Satoh, Kazuyuki Miyamoto, Shusuke Momma, Kenichiro Fukuda, Ryo Higuchi, Hirokazu Ohtaki, Williams A Banks · Journal of clinical biochemistry and nutrition · 2017
Research-use notice
Independent study record
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H2HUBB TAKEAWAY
This narrative review examined the available evidence on molecular hydrogen. Recently, the neuroprotective effects of treatment with molecular hydrogen have been reported in both basic and clinical settings. The reviewed evidence supports molecular hydrogen's therapeutic potential. Additional well-designed studies are needed to clarify clinical safety and effectiveness.
What the Review Examined
The review examined molecular hydrogen in the treatment of acute and chronic neurological conditions: mechanisms of protection and routes of administration.
Main Findings Across the Literature
Molecular hydrogen is well characterized as a scavenger of hydroxyl radicals and peroxynitrite. Recently, the neuroprotective effects of treatment with molecular hydrogen have been reported in both basic and clinical settings. Hydrogen therapy administered in drinking water may be useful for the prevention of neurodegenerative diseases and for reducing the symptoms of acute neuronal conditions.
Authors’ Conclusion
A distinct authors’ conclusion was not available in the source material reviewed by H2HUBB.