Efficacy of Oral Intake of Hydrogen-Rich Jelly Intake on Gingival Inflammation: A Double-Blind, Placebo-Controlled and Exploratory Randomized Clinical Trial.

The publication “Efficacy of Oral Intake of Hydrogen-Rich Jelly Intake on Gingival Inflammation: A Double-Blind, Placebo-Controlled and Exploratory Randomized Clinical Trial.” is organized in H2HUBB under the research focus molecular hydrogen oral health study 2025. The publication is cited as Maruyama T, Takayama E, Tokuno S, Morita M, Ekuni D, Healthcare (Basel, Switzerland), 2025. This randomized controlled trial examined Efficacy of Oral Intake of Hydrogen-Rich Jelly Intake on Gingival Inflammation: A Double-Blind, Placebo-Controlled and Exploratory Randomized Clinical Trial. The abstract describes Human participants; reported duration 14 days. The abstract reports: However, no significant differences were found between groups ( > 0.05). : Administration of hydrogen-rich jelly for 14 days decreased gingival inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.

Molecular hydrogen oral health study 2025 overview

This clinical trial was designed to investigate the safety and efficacy of oral intake of hydrogen-rich jelly against gingival inflammation. : Participants with gingivitis… Because this is human clinical evidence, relevance depends on participant selection, controls, sample size, treatment duration, adherence, outcome measures, and replication.

Study design and hydrogen intervention

Publication type: Randomized controlled trial. Evidence type: Human clinical evidence. Research model or population: Human participants. Randomized: Yes. Blinding: Double-blind. Control status: Placebo-controlled.

Delivery method: Other or not reported. Hydrogen concentration: 40 ppm. Dose or treatment amount: 30 g. Treatment duration: 14 days.

Reported findings and scientific interpretation

For this molecular hydrogen oral health study 2025, the study record reports the following: The abstract reports: However, no significant differences were found between groups ( > 0.05). : Administration of hydrogen-rich jelly for 14 days decreased gingival inflammation.

These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.

How this research record was prepared

H2HUBB organizes bibliographic details, study design information, intervention data, outcomes, limitations, and safety notes from the available scientific source. Automated classification supports database organization, but it does not replace critical reading of the complete paper. Source identifiers, evidence labels, and delivery-method fields are retained so readers can verify the record and compare it with related publications. A missing field means the information was unavailable or not reported in the structured source; it should not be treated as a negative finding.

Limitations, safety, and original source

Limitations: The intervention or follow-up period appears relatively short.

Safety: This clinical trial was designed to investigate the safety and efficacy of oral intake of hydrogen-rich jelly against gingival inflammation. : Participants with gingivitis…

This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.