New Approach in Translational Medicine: Effects of Electrolyzed Reduced Water (ERW) on NF-κB/iNOS Pathway in U937 Cell Line under Altered Redox State.
Sara Franceschelli, Daniela Maria Pia Gatta, Mirko Pesce, Alessio Ferrone, Antonia Patruno, Maria Anna de Lutiis, Alfredo Grilli, Mario Felaco, Fausto Croce, Lorenza Speranza · International journal of molecular sciences · 2016
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
In a laboratory model, electrolyzed Reduced Water (ERW) produced near the cathode during water electrolysis exhibits high pH, high concentration of dissolved hydrogen and an extremely negative redox potential. These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed to determine clinical relevance.
What the Researchers Tested
The study examined in vitro cell-culture laboratory experiment.
How Molecular Hydrogen Was Used
Molecular hydrogen was administered as electrolyzed reduced water (erw) produced near the cathode during water electrolysis exhibits high ph, high concentration of dissolved hydrogen and an extremely negative redox potential. several findings indicate that erw had the ability of a scavenger free radical, which results from hydrogen molecules with a high reducing ability and may participate in the redox regulation of cellular function.
What Molecular Hydrogen Changed
Electrolyzed Reduced Water (ERW) produced near the cathode during water electrolysis exhibits high pH, high concentration of dissolved hydrogen and an extremely negative redox potential.
H₂ Mechanisms / Biological Findings
The source material reviewed did not establish a specific molecular hydrogen mechanism for the reported findings.
Authors’ Conclusion
The authors concluded that , ERW can protect the cellular redox balance, reducing the risk of several diseases with altered cellular homeostasis such as inflammation.