Neuroprotective Effects of Molecular Hydrogen: A Critical Review.
Wei Chen, Han-Ting Zhang, Shu-Cun Qin · Neuroscience bulletin · 2021
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
This narrative review examined the available molecular-hydrogen literature. Further, H₂ is easy to use and has neuroprotective effects with no major side-effects, indicating that H₂ administration is a potential therapeutic strategy in clinical settings. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
What the Findings Mean
H2HUBB reviewed this publication as a synthesis of molecular-hydrogen research and summarizes the outcomes emphasized by the authors. Further, H₂ is easy to use and has neuroprotective effects with no major side-effects, indicating that H₂ administration is a potential therapeutic strategy in clinical settings.
What the Researchers Studied
The authors reviewed neuroprotective Effects of Molecular Hydrogen: A Critical Review.
What Effects Did Molecular Hydrogen Have?
Molecular hydrogen (H₂) is a physiologically inert gas. More specifically, H₂ has protective effects against a variety of diseases, particularly nervous system disorders, which include ischemia/reperfusion injury, traumatic injury, subarachnoid hemorrhage, neuropathic pain, neurodegenerative diseases, cognitive dysfunction induced by surgery and anesthesia, anxiety, and depression. Further, H₂ is easy to use and has neuroprotective effects with no major side-effects, indicating that H₂ administration is a potential therapeutic strategy in clinical settings. The authors concluded that meanwhile, the researchers review the effectiveness and safety of H₂ in the treatment of various nervous system diseases based on preclinical and clinical studies, leading to the conclusion that H₂ can be a simple and effective clinical therapy for CNS diseases such as ischemia-reperfusion brain injury, Parkinson's disease, and diseases characterized by cognitive dysfunction.
Why These Findings Matter
The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
How Strong Is This Evidence?
This is review or synthesis evidence (narrative review).
Technical Study Details
H2HUBB classifies this publication as narrative review with review or synthesis evidence. The study used a narrative review.
Limitations and Safety
No separate limitations or safety findings were identified in the source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.