Oral Administration of Hydrogen-rich Water: Biomedical Activities, Potential Mechanisms, and Clinical Applications.
Fanxianzi Meng, Zhichao Liu, Shucun Qin, Boyan Liu · Current pharmaceutical design · 2025
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
This narrative review examined the basic research and clinical applications of HRW consumption to support its use for daily health and clinical treatment. Clinically, HRW has been used for adjuvant treatment, disease prevention, and quality of life improvement. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
What the Findings Mean
H2HUBB reviewed this publication as a synthesis of molecular-hydrogen research and summarizes the outcomes emphasized by the authors. Clinically, HRW has been used for adjuvant treatment, disease prevention, and quality of life improvement.
What the Researchers Studied
The authors reviewed the basic research and clinical applications of HRW consumption to support its use for daily health and clinical treatment.
What Effects Did Molecular Hydrogen Have?
Molecular hydrogen (H₂) is considered a biological antioxidant. Hydrogen-rich Water (HRW) is regular water that contains dissolved H₂ and has become more widely used in recent years. Hypotheses about the mechanisms of H₂ include the direct scavenging of toxic free radicals, the Fe-porphyrin biosensor hypothesis, the effect of H₂ on biological enzymes, the lipoprotein regulation of H₂, and H₂ acting on the intestinal barrier. Clinically, HRW has been used for adjuvant treatment, disease prevention, and quality of life improvement.
Why These Findings Matter
The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
How Strong Is This Evidence?
This is review or synthesis evidence (narrative review).
Technical Study Details
H2HUBB classifies this publication as narrative review with review or synthesis evidence. The study used a narrative review. The hydrogen delivery method was hydrogen-rich water.
Limitations and Safety
No separate limitations or safety findings were identified in the source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.