Protective effects of hydrogen-rich saline in uncontrolled hemorrhagic shock.
Zunmin DU, Haipeng Jia, Jing Liu, Xiaomin Zhao, Yun Wang, Xuejun Sun · Experimental and therapeutic medicine · 2014
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
Hydrogen is considered to be a novel antioxidant as it inhibits inflammation, removes oxygen-derived free radicals and reduces oxidative damage. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.
What the Researchers Studied
The study examined rats.
How Molecular Hydrogen Was Used
The rats were randomly divided into: Group A (sham-operated group), Group B [shock + intravenously (IV) injected saline], Group C (shock + IV-injected hydrogen-rich saline), Group D [shock + intraperitoneally (IP) injected saline] and Group E (shock + IP-injected hydrogen-rich saline). , itravenous injection of hydrogen-rich saline is more effective than intraperitonal injection.
What the Researchers Found
Hydrogen is considered to be a novel antioxidant as it inhibits inflammation, removes oxygen-derived free radicals and reduces oxidative damage.
H₂ Mechanisms / Biological Findings
Hydrogen is considered to be a novel antioxidant as it inhibits inflammation, removes oxygen-derived free radicals and reduces oxidative damage.
Authors’ Conclusion
The authors concluded that , itravenous injection of hydrogen-rich saline is more effective than intraperitonal injection.