Preclinical animal evidenceAnimal studyhydrogen-rich water

The healing effect of hydrogen-rich water on acute radiation-induced skin injury in rats.

Ping Zhou, Bing Lin, Peng Wang, Tao Pan, Shun Wang, Weisi Chen, Shaowen Cheng, Sha Liu · Journal of radiation research · 2019

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Research-use notice

Independent study record

Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.

H2HUBB Research Library branded molecular hydrogen research image

Primary topic Hydrogen Water Research

Evidence type Preclinical animal evidence

Publication type Animal study

Hydrogen method hydrogen-rich water

H2HUBB TAKEAWAY

In rats, the healing time was shortened in the two HRW-treated groups (P < 0.05). These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.

What the Findings Mean

H2HUBB reviewed how hydrogen-rich water affected the outcomes measured in rats. The healing time was shortened in the two HRW-treated groups (P < 0.05).

What the Researchers Studied

The researchers studied rats. The study used a preclinical animal experiment.

What Effects Did Molecular Hydrogen Have?

The healing time was shortened in the two HRW-treated groups (P < 0.05). The authors concluded that the data indicate that HRW accelerates wound healing of radiation-induced skin lesions through anti-oxidative and anti-inflammatory effects, suggesting that HRW has a healing effect on acute radiation-mediated skin injury, and that this is dependent on the concentration of the hydrogen.

Why These Findings Matter

These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.

How Strong Is This Evidence?

This is preclinical animal evidence from a preclinical animal experiment. It is most informative for the disease model, mechanisms, biomarkers, and outcomes directly measured in the study.

Technical Study Details

H2HUBB classifies this publication as animal study with preclinical animal evidence. The research population or model was rats. The study used a preclinical animal experiment. The hydrogen delivery method was hydrogen-rich water. The reported hydrogen concentration was 1.0 mg/L H₂.

Limitations and Safety

No separate limitations or safety findings were identified in the source text available to H2HUBB.

Original Study and H2HUBB Research Context

H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.

Study Record

Primary topic: Hydrogen Water Research
Evidence type: Preclinical animal evidence
Publication type: Animal study
Delivery method: hydrogen-rich water
DOI: 10.1093/jrr/rry074
PMID: 30260398
PMCID: PMC6373674
Open access: Yes
Verification: Abstract reviewed
Link status: Accessible

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