Hydrogen Gas via Extracorporeal Membrane Oxygenation and Its Effects on Oxidative Stress, Coagulation, and Inflammation: An Ex Vivo Model.

This uncontrolled human study examined Hydrogen Gas via Extracorporeal Membrane Oxygenation and Its Effects on Oxidative Stress, Coagulation, and Inflammation: An Ex Vivo Model. The abstract describes Human participants; sample size 4; reported duration 6 hours. The abstract reports: Hydrogen exposure significantly reduced collagen (p = 0.01), TRAP-6 (p = 0.04), and ADP-induced (p = 0.04) platelet aggregation and showed a trend toward…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Therapy for SLE-PAH: Case Report on Immune Marker Modulation

This case report or case series examined Molecular Hydrogen Therapy for SLE-PAH: Case Report on Immune Marker Modulation. The abstract describes Human participants. The abstract reports: This case study highlights the potential efficacy of molecular hydrogen therapy in a patient with SLE-PAD and decompensated right-sided heart failure precipitated by sepsis.…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Three hydrogen-rich solutions protect against intestinal injury in uncontrolled hemorrhagic shock.

This uncontrolled human study examined Three hydrogen-rich solutions protect against intestinal injury in uncontrolled hemorrhagic shock. The abstract describes Human participants. The abstract reports: Evidence showed that hydrogen inhibited inflammation and reduced oxidative damage. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective Role of Hydrogen Gas on Oxidative Damage and Apoptosis in Intestinal Porcine Epithelial Cells (IPEC-J2) Induced by Deoxynivalenol: A Preliminary Study.

This in vitro or cellular study examined Protective Role of Hydrogen Gas on Oxidative Damage and Apoptosis in Intestinal Porcine Epithelial Cells (IPEC-J2) Induced by Deoxynivalenol: A Preliminary Study. The abstract describes Epithelial cell model. The abstract reports: Our results demonstrated that the 5 μM DON significantly caused cytotoxicity to IPEC-J2 cells by reducing cell viability and increasing lactate dehydrogenase release in…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Treatment Protects Mice Against Chronic Pancreatitis by Restoring Regulatory T Cells Loss.

This uncontrolled human study examined Hydrogen Treatment Protects Mice Against Chronic Pancreatitis by Restoring Regulatory T Cells Loss. The abstract describes Human participants. The abstract reports: Hydrogen treatment showed reliable benefits in controlling the severity of chronic pancreatitis. Our study supported that hydrogen could be used as a novel treatment…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Daily ingestion of alkaline electrolyzed water containing hydrogen influences human health, including gastrointestinal symptoms.

This randomized controlled trial examined Daily ingestion of alkaline electrolyzed water containing hydrogen influences human health, including gastrointestinal symptoms. The abstract describes Human participants. The abstract reports: And for the patients with gastrointestinal symptoms, drinking AEW has been found to be effective in relieving gastrointestinal symptoms. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effect of molecular hydrogen saturated alkaline electrolyzed water on disuse muscle atrophy in gastrocnemius muscle.

This animal study examined Effect of molecular hydrogen saturated alkaline electrolyzed water on disuse muscle atrophy in gastrocnemius muscle. The abstract describes Rat model; reported duration 3 weeks. The abstract reports: We showed that 8-OHdG, but not MDA, significantly increased by 149% and 145% in HU-NW and HU-AEW, respectively, when compared with CONT. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice.

This animal study examined Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice. The abstract describes Mouse model; reported duration 4 weeks. The abstract reports: Results of 16S rRNA gene sequencing analyses showed that the relative abundances of 20 taxa differed significantly in AEW-administered mice. This is an automated editorial draft based on the abstract and requires source review before publication.

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A preliminary therapeutic study of the effects of molecular hydrogen on intestinal dysbiosis and small intestinal injury in high-fat diet-loaded senescence-accelerated mice.

This animal study examined A preliminary therapeutic study of the effects of molecular hydrogen on intestinal dysbiosis and small intestinal injury in high-fat diet-loaded senescence-accelerated mice. The abstract describes Mouse model; sample size 10. The abstract reports: Our findings suggest that treatment with molecular hydrogen may affect microbiota profiling and suppress intestinal injury in HFD-loaded SAMP8. This is an automated editorial draft based on the abstract and requires source review before publication.

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Recent advances in studies of molecular hydrogen in the treatment of pancreatitis.

This narrative review examined Recent advances in studies of molecular hydrogen in the treatment of pancreatitis. The abstract describes Published literature review. The abstract reports: Pancreatitis is an inflammatory disease of the pancreas characterized by acinar cell injury and is associated with the abnormal release of trypsin, which results…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.

This animal study examined Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence. The abstract describes Mouse model. The abstract reports: Moreover, this result was consistent with the downregulation of expression of the oxidative stress hallmark OGG1. This is an automated editorial draft based on the abstract and requires source review before publication.

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An Immunohistochemical Study of the Increase in Antioxidant Capacity of Corneal Epithelial Cells by Molecular Hydrogen, Leading to the Suppression of Alkali-Induced Oxidative Stress

This in vitro or cellular study examined An Immunohistochemical Study of the Increase in Antioxidant Capacity of Corneal Epithelial Cells by Molecular Hydrogen, Leading to the Suppression of Alkali-Induced Oxidative Stress. The abstract describes Epithelial cell model. The abstract reports: The results obtained with immunohistochemistry and pachymetry showed that in the corneas of H-pretreated eyes, slight oxidative stress appeared followed by an increased expression…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effect of molecular hydrogen against oxidative stress caused by peroxynitrite derived from nitric oxide in rat retina.

This animal study examined Protective effect of molecular hydrogen against oxidative stress caused by peroxynitrite derived from nitric oxide in rat retina. The abstract describes Rat model. The abstract reports: H2 reduces cellular peroxynitrite, a highly toxic reactive nitrogen species. Thus, H2 may be an effective and novel clinical tool for treating glaucoma and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury.

This animal study examined Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury. The abstract describes Rat model; reported duration 60 minutes. The abstract reports: H(2) has no known toxic effects on the human body. Thus, the results suggest that H(2)-loaded eye drops are a highly useful neuroprotective and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activated retinal microglia cells.

This in vitro or cellular study examined Molecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activated retinal microglia cells. The abstract describes Cell culture / in vitro model. The abstract reports: The results in the present study indicate that miR-9, miR-199 and miR-21 play an important role in the anti-inflammatory regulation of LPS-activated microglia cells…. This is an automated editorial draft based on the abstract and requires source review before publication.

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