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Spinal peroxynitrite contributes to remifentanil-induced postoperative hyperalgesia via enhancement of divalent metal transporter 1 without iron-responsive element-mediated iron accumulation in rats.

By Aug 28, 2026 0 Comments

In rats, eliminating peroxynitrite with hydrogen-rich saline protected against hyperalgesia and attenuated DMT1(-)IRE overexpression and iron accumulation. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…

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