Exploring the Potential of H2 Therapy in Reducing Surgical Complications: A Review on Anti-inflammatory, Antioxidant, and Anti-fibrotic Mechanisms

This narrative review examined Exploring the Potential of H2 Therapy in Reducing Surgical Complications: A Review on Anti-inflammatory, Antioxidant, and Anti-fibrotic Mechanisms. The abstract describes Published literature review. The abstract reports: Hydrogen is demonstrated to attenuate the early inflammatory response by down-regulating proinflammatory cytokines alongside its anti-oxidative and anti-fibrotic effects. As a potential therapeutic agent…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Research Progress of Hydrogen on Chronic Nasal Inflammation.

This narrative review examined Research Progress of Hydrogen on Chronic Nasal Inflammation. The abstract describes Published literature review. The abstract reports: Therefore, anti-oxidative stress is a direction of research for the treatment of chronic nasal mucosal inflammatory diseases.Hydrogen, as a medically therapeutic gas, has been…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen as a novel regulator of cellular pyroptosis: mechanistic insights and therapeutic implications

This narrative review examined Molecular hydrogen as a novel regulator of cellular pyroptosis: mechanistic insights and therapeutic implications. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.

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Potent anti-inflammatory responses: Role of hydrogen in IL-1α dominated early phase systemic inflammation.

This animal study examined Potent anti-inflammatory responses: Role of hydrogen in IL-1α dominated early phase systemic inflammation. The abstract describes Mouse model. The abstract reports: The results suggested that hydrogen is potentially inhibitive against inflammation by inhibiting HIF-1α and IL-1α release at early occurrence. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model.

This uncontrolled human study examined Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model. The abstract describes Human participants; reported duration 60 min. The abstract reports: Recently, it has been suggested that hydrogen gas (H2) exerts a therapeutic antioxidant activity by selectively reducing hydroxyl radical (•OH, the most cytotoxic reactive…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effect of molecular hydrogen on uterine inflammation during preterm labour.

This animal study examined Effect of molecular hydrogen on uterine inflammation during preterm labour. The abstract describes Mouse model. The abstract reports: Our previous studies demonstrated that molecular hydrogen (H), an anti-inflammatory agent, prevented inflammation-induced impairment in foetal brain and lung tissues in lipopolysaccharide (LPS)-induced rodent…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Combating Oxidative Stress and Inflammation in COVID-19 by Molecular Hydrogen Therapy: Mechanisms and Perspectives.

This narrative review examined Combating Oxidative Stress and Inflammation in COVID-19 by Molecular Hydrogen Therapy: Mechanisms and Perspectives. The abstract describes Published literature review. The abstract reports: This situation results in impaired gas exchange, hypoxia, and other sequelae that lead to multisystem organ failure and death. This is an automated editorial draft based on the abstract and requires source review before publication.

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H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain.

This animal study examined H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain. The abstract describes Rat model. The abstract reports: We found that H2 clearly inhibited hyperalgesia and allodynia in neuropathic pain and also attenuated the pro-inflammatory cytokines TNF-α, IL-1β, and high-mobility group box…. This is an automated editorial draft based on the abstract and requires source review before publication.

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In Situ Nanoreactor for Photosynthesizing H Gas To Mitigate Oxidative Stress in Tissue Inflammation.

This animal study examined In Situ Nanoreactor for Photosynthesizing H Gas To Mitigate Oxidative Stress in Tissue Inflammation. The abstract describes Mouse model. The abstract reports: Experimental results indicate that the Lip NR system that can photosynthesize H gas has great potential for mitigating oxidative stress in tissue inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.

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The immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice.

This animal study examined The immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice. The abstract describes Mouse model. The abstract reports: In the case of infected groups, the group fed ERW (ERW+E. hortense group) showed the result that IL-4, IL-5, IL-10 and Ig A expression…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators.

This in vitro or cellular study examined Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators. The abstract describes Cell culture / in vitro model. The abstract reports: We previously showed that H2 acts as a novel antioxidant to protect cells against oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.

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Combination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model

This uncontrolled human study examined Combination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model. The abstract describes Human participants. The abstract reports: The results showed that the inhalation of H (2%) or hyperoxia (98%) alone improved the 14-day survival rate of ZY-challenged mice from 20 to…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate.

This animal study examined Hydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.

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Heme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages.

This in vitro or cellular study examined Heme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages. The abstract describes Cell culture / in vitro model. The abstract reports: Molecular hydrogen exerts a regulating role in the release of pro- and anti-inflammatory cytokines in LPS-stimulated macrophages, and this effect is at least partly…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch.

This uncontrolled human study examined Hydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch. The abstract describes Human participants. This is an automated editorial draft based on the abstract and requires source review before publication.

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