Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury.
This uncontrolled human study examined Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury. The abstract describes Human participants. The abstract reports: Inhalation of hydrogen (H(2)) gas has been demonstrated to limit the infarct volume of brain and liver by reducing ischemia-reperfusion injury in rodents. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreH2 inhibits TNF-α-induced lectin-like oxidized LDL receptor-1 expression by inhibiting nuclear factor κB activation in endothelial cells
This animal study examined H2 inhibits TNF-α-induced lectin-like oxidized LDL receptor-1 expression by inhibiting nuclear factor κB activation in endothelial cells. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Therapy in Cardiovascular and Metabolic Diseases: from Bench to Bedside.
This narrative review examined Hydrogen Therapy in Cardiovascular and Metabolic Diseases: from Bench to Bedside. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas protects against myocardial stunning and infarction in swine
This animal study examined Inhalation of hydrogen gas protects against myocardial stunning and infarction in swine. The abstract describes Porcine model. The abstract reports: Inhalation of 2% H(2) gas improves myocardial stunning, and inhalation of 4% but not 2% H(2) gas reduces myocardial infarct size in swine. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreImage-Guided Hydrogen Gas Delivery for Protection from Myocardial Ischemia-Reperfusion Injury via Microbubbles.
This animal study examined Image-Guided Hydrogen Gas Delivery for Protection from Myocardial Ischemia-Reperfusion Injury via Microbubbles. The abstract describes Rat model. The abstract reports: However, H is sparingly soluble in water, resulting in its poor bioavailability in blood and damaged tissues. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePost-reperfusion hydrogen gas treatment ameliorates ischemia reperfusion injury in rat livers from donors after cardiac death: a preliminary study.
This animal study examined Post-reperfusion hydrogen gas treatment ameliorates ischemia reperfusion injury in rat livers from donors after cardiac death: a preliminary study. The abstract describes Rat model. The abstract reports: H was observed to ameliorate IRI in the DCD liver by maintaining microcirculation, mitochondrial functions, and redox status, as well as suppressing the cytoplasmic…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConflicting findings on the effectiveness of hydrogen therapy for ameliorating vascular leakage in a 5-day post hypoxic-ischemic survival piglet model.
This animal study examined Conflicting findings on the effectiveness of hydrogen therapy for ameliorating vascular leakage in a 5-day post hypoxic-ischemic survival piglet model. The abstract describes Porcine model. The abstract reports: The ratio of albumin stained to unstained areas was analyzed and found to be lower in the H group than in the other groups,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe Anti-inflammatory Effect of Hydrogen on Lung Transplantation Model of Pulmonary Microvascular Endothelial Cells During Cold Storage Period.
This in vitro or cellular study examined The Anti-inflammatory Effect of Hydrogen on Lung Transplantation Model of Pulmonary Microvascular Endothelial Cells During Cold Storage Period. The abstract describes Endothelial cell model; reported duration 4 hours. The abstract reports: Hydrogen-attenuated inflammatory response in a PMVECs lung transplantation model during cold storage. The effect may be achieved by inhibition of p38 MAPK and NF-κB…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-containing saline alleviates pressure overload-induced interstitial fibrosis and cardiac dysfunction in rats.
This animal study examined Hydrogen-containing saline alleviates pressure overload-induced interstitial fibrosis and cardiac dysfunction in rats. The abstract describes Rat model. The abstract reports: These results indicate that HCS treatment can improve cardiac function by reducing interstitial fibrosis in pressure‑overloaded rats through its anti‑oxidative properties and via suppression…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInsufflation of hydrogen gas restrains the inflammatory response of cardiopulmonary bypass in a rat model.
This uncontrolled human study examined Insufflation of hydrogen gas restrains the inflammatory response of cardiopulmonary bypass in a rat model. The abstract describes Human participants. The abstract reports: We suggest that H₂ insufflation is a possible new potential therapy for counteracting CPB-induced systemic inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas protects against serum and glucose deprivation‑induced myocardial injury in H9c2 cells through activation of the NF‑E2‑related factor 2/heme oxygenase 1 signaling pathway.
This animal study examined Hydrogen gas protects against serum and glucose deprivation‑induced myocardial injury in H9c2 cells through activation of the NF‑E2‑related factor 2/heme oxygenase 1 signaling pathway. The abstract describes Rat model. The abstract reports: Exposure of the cells to SGD also resulted in significant increases in HO‑1 expression and nuclear Nrf2 levels, and the HO‑1 inhibitor ZnPP IX and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreBreathing nitric oxide plus hydrogen gas reduces ischemia-reperfusion injury and nitrotyrosine production in murine heart.
This animal study examined Breathing nitric oxide plus hydrogen gas reduces ischemia-reperfusion injury and nitrotyrosine production in murine heart. The abstract describes Mouse model; reported duration 60 min. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen protects mice against polymicrobial sepsis by ameliorating endothelial dysfunction via an Nrf2/HO-1 signaling pathway.
This animal study examined Molecular hydrogen protects mice against polymicrobial sepsis by ameliorating endothelial dysfunction via an Nrf2/HO-1 signaling pathway. The abstract describes Mouse model. The abstract reports: We found that molecular hydrogen (H2) exerts an anti-inflammatory effect. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich medium suppresses the generation of reactive oxygen species, elevates the Bcl-2/Bax ratio and inhibits advanced glycation end product-induced apoptosis.
This in vitro or cellular study examined Hydrogen-rich medium suppresses the generation of reactive oxygen species, elevates the Bcl-2/Bax ratio and inhibits advanced glycation end product-induced apoptosis. The abstract describes Endothelial cell model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen prevents corneal endothelial damage in phacoemulsification cataract surgery : Scientific Reports
This animal study examined Hydrogen prevents corneal endothelial damage in phacoemulsification cataract surgery : Scientific Reports. The abstract describes Rabbit model. The abstract reports: ESR showed a significantly decreased signal magnitude, and fluorescence intensity by oxidized HPF was significantly less in the H2-dissolved solution. This is an automated editorial draft based on the abstract and requires source review before publication.
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