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In a laboratory model, the subsequent in vitro experiments showed that H₂ treatment inhibited the phosphorylation of extracellular signal-regulated kinase (ERK), c-jun N-terminal kinase (JNK), and p38 MAPK, and activated NF-κB and the expression of tumor necrosis factor α and interleukin-1β, while…
Read ArticleIn SH-SY5Y cells, H₂ treatment significantly improved cell viability, attenuated oxidative stress and mitochondrial dysfunction, and enhanced mitophagy via activation of the PINK1/Parkin pathway. The authors linked these…
Read ArticleIn mice, compared with the sham operation and hydrogen control groups, in the sepsis group, the number of normal pyramidal neurons in the hippocampal CA1 region was markedly…
Read ArticleThis publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
Read ArticleThe researchers observed a significant increase in the concentration of H₂ in the placenta after the oral administration of hydrogen-saturated water to the mothers, with less placental oxidative…
Read ArticleIn mice, as shown in Figure 2h, PFOB NEs have an excellent hydrogen‐carrying capacity of ≈ 6 mM, which is about eight times higher than that of water.…
Read ArticleIn rabbits, here, the researchers found that I/R-challenged animals showed significant spinal cord damage characterized by the decreased numbers of normal motor neurons and hind-limb motor dysfunction, which…
Read ArticleIn mice, hydrogen gas concentrations in maternal livers and whole fetuses in EFA-FOS were significantly higher than those in CONT and EFA, respectively (P <.05). These preclinical findings…
Read ArticleIn rats, however, the reduction of the expression of 8-OHdG, the decrease in the neuronal injury in the hippocampal CA1 sector, and the attenuation in brain water content…
Read ArticleIn rats, exercise increased cleaved caspase-3 expression, and H₂ reduced this response. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways…
Read ArticleIn a laboratory model, molecular hydrogen inhalations in both regimens caused a decrease in the number of circulating endothelial cells; the most pronounced effect was observed after repeated…
Read ArticleIn mice, intermittent hypoxia significantly increased plasma levels of low- and very low-density cholesterol and the amount of 4-hydroxy-2-nonenal-modified protein adducts in the LV myocardium. These preclinical findings…
Read ArticleIn mice, compared with WT-H₂ mice, 5xFAD-Veh mice exhibited increased BAX expression ( p < 0.05) and reduced BCL-2 expression, whereas H₂ treatment in 5xFAD-H₂ mice decreased BAX,…
Read ArticleThe researchers found that administering a persistent H₂-generating supplement increased the human exhaled H₂ concentration (p < 0.01) and improved tear stability (p < 0.01) and dry eye…
Read ArticleThis publication examined molecular hydrogen using the study design reported by the authoritative source. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a…
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