What’s new in Medical Gas Research: Highlights for 2015.
This publication is a scientific hypothesis or perspective about molecular hydrogen and identifies directions for further research.
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Latest Molecular Hydrogen Articles
1,249 Articles
Natural reduced water suppressed anxiety and protected the heightened oxidative stress in rats.
In rats, no significant deference between the natural reduced water group (287.9±7.7 s) and the distilled water group (291.8±5.4 s) was observed in the black and white box…
Read ArticleHydrogen Gas Therapy in Schizophrenia: Potential Neuroprotective Effects From an Animal Study.
In male C57BL/6 mice, mK-801 administration significantly reduced HORAC levels, whereas hydrogen gas therapy markedly restored them. These preclinical findings add evidence about the molecular-hydrogen effects, outcomes, and…
Read ArticleMolecular Hydrogen as a Regulator of Mitochondrial Quality Control and Metabolic Reprogramming.
This narrative review examined the available molecular-hydrogen literature. The biological effects of molecular hydrogen are moving beyond the traditional explanatory framework of "selective antioxidation." This article systematically integrates…
Read ArticleInhibitory effects of hydrogen on in vitro platelet activation and in vivo prevention of thrombosis formation.
In rats, hRS decreased P-selectin expression, release of thromboxane B2, ROS, and fibrinogen binding, but enhanced NO levels in H₂O₂-exposed platelets. These preclinical findings add evidence supporting molecular…
Read ArticleConventional drug acts as a “rifle gun” while hydrogen as a “machine gun”.
This narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleTwo-Dimensional Mg2 Si Nanosheet-Enabled Sustained Hydrogen Generation for Improved Repair and Regeneration of Deeply Burned Skin.
In a laboratory model, mechanistically, a sustained supply of hydrogen molecules induces anti-inflammatory M2 macrophage polarization in time by enhancing CCL2 (chemokine C-C motif ligand 2) expression to…
Read ArticleNanoparticulate MgH2 ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress.
The researchers observed that anxiety/depression-like behaviors in experimental autoimmune encephalomyelitis (EAE) mice were alleviated by MgH2 treatment. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleHydrogen ventilation combined with mild hypothermia improves short-term neurological outcomes in a 5-day neonatal hypoxia-ischaemia piglet model.
In an animal model, regarding the neurological score, the piglets in the TH-H₂ group consistently had the highest score from day 2 to 5 and showed a significantly…
Read ArticleEngineering a biomimetic bone scaffold that can regulate redox homeostasis and promote osteogenesis to repair large bone defects.
In an animal model, the released hydrogen gas can effectively regulate redox homeostasis and mitigate excessive inflammation, and the silicic acid can promote the proliferation of reparative cells…
Read ArticleHydrogen preconditioning during ex vivo lung perfusion improves the quality of lung grafts in rats.
In a laboratory model, hydrogen administration also promoted mitochondrial biogenesis and significantly decreased lactate production. The authors concluded that preconditioning lung grafts using inhaled hydrogen attenuated these proinflammatory…
Read ArticleStimulating fermentation by the prolonged acceleration of gut transit protects against decompression sickness.
In rats, pEG led to a significant increase in exhaled H₂ (35 ppm [10-73] compared with control 7 ppm [2-15]; p = 0.001). These preclinical findings add evidence…
Read ArticleNIR-Activatable Heterostructured Nanoadjuvant CoP/NiCoP Executing Lactate Metabolism Interventions for Boosted Photocatalytic Hydrogen Therapy and Photoimmunotherapy.
In a laboratory model, under NIR irradiation, CNCP heterojunctions exhibit superior photothermal performance and photocatalytic production of reactive oxygen species and hydrogen. These findings from a laboratory model…
Read ArticleMicrobial hydrogen “manufactory” for enhanced gas therapy and self-activated immunotherapy via reduced immune escape.
In Detection of the production and diffusion of H₂ in MCF-7 cells via MB probe under different treatments, more interestingly, the researchers found that hydrogen therapy induced by…
Read Article[The combined use of inhaled nitric oxide and molecular hydrogen in patients with post-COVID-19 syndrome].
These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence fatigue-related outcomes.
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