Molecular Hydrogen Blog

Hydrogen-rich saline attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of isoflurane-induced oxidative stress, mitochondrial dysfunction, and reduction in ATP levels.

In a laboratory model, hS treatment mitigated isoflurane-induced ROS accumulation, opening of mitochondrial permeability transition pores, reduction in mitochondrial membrane potential, and reduction in cellular ATP levels. The authors concluded that hS attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of…