Safety of inhaled hydrogen gas in healthy mice.

This animal study examined Safety of inhaled hydrogen gas in healthy mice. The abstract describes Mouse model; sample size 25; hydrogen delivered as hydrogen inhalation; reported duration 72 hours. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective Effects of Hydrogen against Low‐Dose Long‐Term Radiation‐Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice

This animal study examined Protective Effects of Hydrogen against Low‐Dose Long‐Term Radiation‐Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice. The abstract describes Mouse model. The abstract reports: And significant differences between the treatment group and the radiation-only groups were observed, showing that H could diminish the detriment induced by LDLTR and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Dose-dependent inhibition of gastric injury by hydrogen in alkaline electrolyzed drinking water.

This uncontrolled human study examined Dose-dependent inhibition of gastric injury by hydrogen in alkaline electrolyzed drinking water. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Hydrogen is effective in relieving the gastric injury induced by aspirin-HCl, and the inhibitory effect is dose-dependent. The reason behind this may be that…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Pharmacokinetics of a single inhalation of hydrogen gas in pigs.

This animal study examined Pharmacokinetics of a single inhalation of hydrogen gas in pigs. The abstract describes Animal model. This is an automated editorial draft based on the abstract and requires source review before publication.

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Biological safety of neutral-pH hydrogen-enriched electrolyzed water upon mutagenicity, genotoxicity and subchronic oral toxicity

This animal study examined Biological safety of neutral-pH hydrogen-enriched electrolyzed water upon mutagenicity, genotoxicity and subchronic oral toxicity. The abstract describes Rat model; reported duration 28 days. The abstract reports: Hydrogen-dissolved water has been suggested to be effective for alleviating the oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma.

This animal study examined Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: These findings suggest that hydrogen-rich saline reduces airway inflammation and remodeling in OVA-exposed mice by inhibiting NF-κB. This is an automated editorial draft based on the abstract and requires source review before publication.

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Pharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs.

This animal study examined Pharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhalation: in vivo rat genotoxicity tests.

This animal study examined Hydrogen inhalation: in vivo rat genotoxicity tests. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Pharmacokinetics of hydrogen after ingesting a hydrogen-rich solution: A study in pigs.

This animal study examined Pharmacokinetics of hydrogen after ingesting a hydrogen-rich solution: A study in pigs. The abstract describes Animal model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 120 min. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective Effects of a Hydrogen-Rich Preservation Solution in a Canine Lung Transplantation Model.

This animal study examined Protective Effects of a Hydrogen-Rich Preservation Solution in a Canine Lung Transplantation Model. The abstract describes Canine model; reported duration 4 hours. The abstract reports: Our results demonstrated that the H-rich preservation solution attenuated ischemia-reperfusion injury in a canine left LTx model. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Ameliorates Anti-Desmoglein 1 Antibody-Induced Pemphigus-Associated Interstitial Lung Disease by Inhibiting Oxidative Stress.

This uncontrolled human study examined Molecular Hydrogen Ameliorates Anti-Desmoglein 1 Antibody-Induced Pemphigus-Associated Interstitial Lung Disease by Inhibiting Oxidative Stress. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Using a BALB/cJGpt mouse model, we demonstrated that anti-Dsg 1 antibodies, but not anti-Dsg 3 antibodies, induced interstitial inflammation and fibrosis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline inhibits tobacco smoke-induced chronic obstructive pulmonary disease by alleviating airway inflammation and mucus hypersecretion in rats.

This animal study examined Hydrogen-rich saline inhibits tobacco smoke-induced chronic obstructive pulmonary disease by alleviating airway inflammation and mucus hypersecretion in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 12 weeks. The abstract reports: ELISA assay showed hydrogen-rich saline lowered the levels of pro-inflammatory cytokines (IL-8 and IL-6) and anti-inflammatory cytokine IL-10 in bronchoalveolar lavage fluid and serum…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline reduces lung injury induced by intestinal ischemia/reperfusion in rats.

This animal study examined Hydrogen-rich saline reduces lung injury induced by intestinal ischemia/reperfusion in rats. The abstract describes Rat model; sample size 30; hydrogen delivered as hydrogen-rich saline. The abstract reports: Hydrogen-rich saline attenuates lung injury induced by intestinal I/R. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhalation ameliorates ventilator-induced lung injury.

This uncontrolled human study examined Hydrogen inhalation ameliorates ventilator-induced lung injury. The abstract describes Human participants; sample size 8; hydrogen delivered as hydrogen inhalation; reported duration 2 hours. The abstract reports: Inhaled hydrogen gas effectively reduced VILI-associated inflammatory responses, at both a local and systemic level, via its antioxidant, anti-inflammatory and antiapoptotic effects. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas inhalation protects against cigarette smoke-induced COPD development in mice.

This animal study examined Hydrogen gas inhalation protects against cigarette smoke-induced COPD development in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: These findings demonstrated that H inhalation could inhibit CS-induced COPD development in mice, which is associated with reduced ERK1/2 and NF-κB-dependent inflammatory responses. This is an automated editorial draft based on the abstract and requires source review before publication.

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