Hydrogen-rich saline attenuates skin ischemia/reperfusion induced apoptosis via regulating Bax/Bcl-2 ratio and ASK-1/JNK pathway.

This animal study examined Hydrogen-rich saline attenuates skin ischemia/reperfusion induced apoptosis via regulating Bax/Bcl-2 ratio and ASK-1/JNK pathway. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results indicate that hydrogen-rich saline could ameliorate ischemia/reperfusion injury and improve flap survival rate by inhibiting the apoptosis factor and, at the same…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effect of hydrogen-rich saline on ischemia/reperfusion injury in rat skin flap.

This animal study examined Protective effect of hydrogen-rich saline on ischemia/reperfusion injury in rat skin flap. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Our findings suggest that HRS mitigates I/R injury by decreasing inflammation and, therefore, has the potential for application as a therapy for improving skin…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Preconditioning with one-time hydrogen gas does not attenuate skin flap ischemia-reperfusion injury in rat models.

This animal study examined Preconditioning with one-time hydrogen gas does not attenuate skin flap ischemia-reperfusion injury in rat models. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Preconditioning with one-time inhaled hydrogen does not attenuate skin flap IR injuries in rat models. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Water Intake Accelerates Oral Palatal Wound Healing via Activation of the Nrf2/Antioxidant Defense Pathways in a Rat Model.

This animal study examined Hydrogen-Rich Water Intake Accelerates Oral Palatal Wound Healing via Activation of the Nrf2/Antioxidant Defense Pathways in a Rat Model. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results of this study support the hypothesis that oral administration of hydrogen-rich water benefits the wound healing process by decreasing oxidative stress and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NC/Nga Mice.

This animal study examined The Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NC/Nga Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water; reported duration 25 days. The abstract reports: The results suggest that HW affects allergic contact dermatitis through modulation of Th1 and Th2 responses in NC/Nga mice. This is an automated editorial draft based on the abstract and requires source review before publication.

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Positive Effects of hydrogen water on 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice.

This animal study examined Positive Effects of hydrogen water on 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: In the present study, we investigated the effect of drinking hydrogen water (HW) on 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis in NC/Nga mice and found that…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen water ameliorates the severity of atopic dermatitis-like lesions and decreases interleukin-1β, interleukin-33, and mast cell infiltration in NC/Nga mice.

This animal study examined Hydrogen water ameliorates the severity of atopic dermatitis-like lesions and decreases interleukin-1β, interleukin-33, and mast cell infiltration in NC/Nga mice. The abstract describes Mouse model; sample size 11; hydrogen delivered as hydrogen water; reported duration 4 weeks. The abstract reports: Levels of serum thymus and activation-regulated chemokine (TARC) and cytokines in the AD lesion were measured by ELISA; and mRNA expression of TARC  and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen ameliorates psoriasis-like skin inflammation via inhibiting the cGAS–STING pathway

This animal study examined Hydrogen ameliorates psoriasis-like skin inflammation via inhibiting the cGAS–STING pathway | Clinical and Experimental Immunology | Oxford Academic. The abstract describes Mouse model; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: In a previous study, we demonstrated in a psoriasis mouse model that hydrogen-rich water, an effective reactive oxygen species (ROS) scavenger, significantly improves disease…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water ameliorates imiquimod-induced psoriasis-like skin lesions and regulates macrophage polarization in dyslipidemic ApoE-deficient mice.

This animal study examined Hydrogen-rich water ameliorates imiquimod-induced psoriasis-like skin lesions and regulates macrophage polarization in dyslipidemic ApoE-deficient mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: The results revealed that HRW significantly reduced plasma triglyceride and total cholesterol levels, increased high-density lipoprotein cholesterol levels, and alleviated skin lesions in mice. This is an automated editorial draft based on the abstract and requires source review before publication.

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Intermittent environmental exposure to hydrogen prevents skin photoaging through reduction of oxidative stress.

This animal study examined Intermittent environmental exposure to hydrogen prevents skin photoaging through reduction of oxidative stress. The abstract describes Mouse model. The abstract reports: Our findings support the notion that long-term, intermittent environmental exposure to hydrogen gas in daily life has a beneficial effect on UVA-induced photoaging. Geriatr…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effect and mechanism of hydrogen‐rich bath on mice with imiquimod‐induced psoriasis

This animal study examined Effect and mechanism of hydrogen‐rich bath on mice with imiquimod‐induced psoriasis. The abstract describes Mouse model; hydrogen delivered as hydrogen water and hydrogen bath and topical hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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Local Treatment of Hydrogen-Rich Saline Promotes Wound Healing In Vivo by Inhibiting Oxidative Stress via Nrf-2/HO-1 Pathway.

This animal study examined Local Treatment of Hydrogen-Rich Saline Promotes Wound Healing In Vivo by Inhibiting Oxidative Stress via Nrf-2/HO-1 Pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results showed that local treatment of hydrogen-rich saline shortened wound closure time and reduced the level of proinflammatory cytokines and lipid peroxidation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-generating Si-based agent protects against skin flap ischemia-reperfusion injury in rats.

This animal study examined Hydrogen-generating Si-based agent protects against skin flap ischemia-reperfusion injury in rats. The abstract describes Rat model. The abstract reports: The Si-based agent suppressed oxidative stress, apoptosis, and inflammatory reactions resulting from I/R injury, thereby contributing to improvements in skin flap survival. This is an automated editorial draft based on the abstract and requires source review before publication.

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Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model.

This animal study examined Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 5 min. The abstract reports: Many studies have demonstrated the therapeutic effects of hydrogen in pathological conditions such as inflammation; however, little is known about its prophylactic effects. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Therapeutic Effects of Oral Intake of Hydrogen Rich Water on Cutaneous Wound Healing in Dogs.

This animal study examined The Therapeutic Effects of Oral Intake of Hydrogen Rich Water on Cutaneous Wound Healing in Dogs. The abstract describes Animal model; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: We observed that HRW wounds showed an increased rate of wound healing, and a faster average healing time compared with DW. This is an automated editorial draft based on the abstract and requires source review before publication.

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