Role of Molecular Hydrogen in Skin Diseases and its Impact in Beauty.

This uncontrolled human study examined Role of Molecular Hydrogen in Skin Diseases and its Impact in Beauty. The abstract describes Human participants. The abstract reports: In today's society, healthy skin and a beautiful appearance are considered the foundation of general well-being. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen: current knowledge on mechanism in alleviating free radical damage and diseases

This narrative review examined Molecular hydrogen: current knowledge on mechanism in alleviating free radical damage and diseases. The abstract describes Published literature review. The abstract reports: All these pathological damages are concomitant with overproduction of reactive oxygen species (ROS) where molecular hydrogen has been widely demonstrated as a selective antioxidant. This is an automated editorial draft based on the abstract and requires source review before publication.

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Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies.

This randomized controlled trial examined Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies. The abstract describes Human participants; sample size 10; reported duration 12 weeks. The abstract reports: Hydrogen-enriched water improves mitochondrial dysfunction in MM and inflammatory processes in PM/DM. Less prominent effects with the double-blind trial compared to the open-label trial…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Modulation of the oxidative plasmatic state in gastroesophageal reflux disease with the addition of rich water molecular hydrogen: A new biological vision.

This uncontrolled human study examined Modulation of the oxidative plasmatic state in gastroesophageal reflux disease with the addition of rich water molecular hydrogen: A new biological vision. The abstract describes Human participants; reported duration 3 months. The abstract reports: Overall results demonstrated that an optimal oxidative balance can be restored and GERD symptoms can be reduced rapidly via the integration of ERW in…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The protective effects of hydrogen on HO-1 expression in the brainafter focal cerebral ischemia reperfusion in rats.

This animal study examined The protective effects of hydrogen on HO-1 expression in the brainafter focal cerebral ischemia reperfusion in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results suggest that the neuroprotective effects of hydrogen may be mediated by promoting HO-1 expression and attenuated the oxidative injury. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen mitigates traumatic brain injury-induced lung injury via NLRP3 inflammasome inhibition.

This animal study examined Molecular hydrogen mitigates traumatic brain injury-induced lung injury via NLRP3 inflammasome inhibition. The abstract describes Mouse model. The abstract reports: 2% H can protect against TBI-induced lung injury by inhibiting NLRP3 inflammasome activation, thereby alleviating inflammation and inhibiting apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Magnesium silicate nanosheets enable sustained hydrogen release to attenuate secondary brain injury following intracerebral hemorrhage.

This animal study examined Magnesium silicate nanosheets enable sustained hydrogen release to attenuate secondary brain injury following intracerebral hemorrhage. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: RESULTS: MGNs exhibited a two-dimensional structure and enabled sustained hydrogen release, particularly under acidic conditions. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats – A possible new hydrogen resource for clinical use.

This animal study examined Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats – A possible new hydrogen resource for clinical use. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Pathologically, tissues from rats in hydrogen inhalation group showed no significant difference compared with the control group in HE staining pictures. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhaling Hydrogen Ameliorates Early Postresuscitation EEG Characteristics in an Asphyxial Cardiac Arrest Rat Model

This uncontrolled human study examined Inhaling Hydrogen Ameliorates Early Postresuscitation EEG Characteristics in an Asphyxial Cardiac Arrest Rat Model. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Recent animal studies found that hydrogen inhalation after CA greatly improved neurological outcomes by selectively neutralizing highly reactive oxidants, but the effect of hydrogen…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of 2% Hydrogen Improves Survival Rate and Attenuates Shedding of Vascular Endothelial Glycocalyx in Rats with Heat Stroke.

This animal study examined Inhalation of 2% Hydrogen Improves Survival Rate and Attenuates Shedding of Vascular Endothelial Glycocalyx in Rats with Heat Stroke. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results showed that 2% hydrogen gas significantly improved survival in the heat-stroked rats and partially preserved the thickness of the endothelial glycocalyx. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen saline offers neuroprotection by reducing oxidative stress in a focal cerebral ischemia-reperfusion rat model

This animal study examined Hydrogen saline offers neuroprotection by reducing oxidative stress in a focal cerebral ischemia-reperfusion rat model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These findings demonstrated hydrogen saline is neuroprotective when administered within 6 h after ischemia. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas Treatment Improves the Neurological Outcome After Traumatic Brain Injury Via Increasing miR-21 Expression.

This animal study examined Hydrogen Gas Treatment Improves the Neurological Outcome After Traumatic Brain Injury Via Increasing miR-21 Expression. The abstract describes Rat model. The abstract reports: Here, we found that H2 treatment significantly increased the expression of miR-21 in brain from 6 h to 3 d after TBI. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen improves cell viability partly through inhibition of autophagy and activation of PI3K/Akt/GSK3β signal pathway in a microvascular endothelial cell model of traumatic brain injury.

This in vitro or cellular study examined Hydrogen improves cell viability partly through inhibition of autophagy and activation of PI3K/Akt/GSK3β signal pathway in a microvascular endothelial cell model of traumatic brain injury. The abstract describes Endothelial cell model. The abstract reports: More importantly, inhibition of PI3 K/Akt/GSK3β signal pathway or activation of autophagy reduced the protective effect of hydrogen on cell viability, indicating that such protective…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas therapy improves survival rate and neurological deficits in subarachnoid hemorrhage rats: a pilot study.

This animal study examined Hydrogen gas therapy improves survival rate and neurological deficits in subarachnoid hemorrhage rats: a pilot study. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation; reported duration 2 hours. The abstract reports: Our results correlate well with the proposed mechanisms of hydrogen gas therapy within the literature. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas post‑conditioning attenuates early neuronal pyroptosis in a rat model of subarachnoid hemorrhage through the mitoKATP signaling pathway

This animal study examined Hydrogen gas post‑conditioning attenuates early neuronal pyroptosis in a rat model of subarachnoid hemorrhage through the mitoKATP signaling pathway. The abstract describes Rat model. The abstract reports: Therefore, these observations suggest that post-conditioning with hydrogen gas ameliorated SAH-induced neuronal pyroptosis at least in part through the mitoK/ERK1/2/p38 MAPK signaling pathway. This is an automated editorial draft based on the abstract and requires source review before publication.

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