Hydrogen-rich saline ameliorates hippocampal neuron apoptosis through up-regulating the expression of cystathionine β-synthase (CBS) after cerebral ischemia- reperfusion in rats.
This animal study examined Hydrogen-rich saline ameliorates hippocampal neuron apoptosis through up-regulating the expression of cystathionine β-synthase (CBS) after cerebral ischemia- reperfusion in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 2 hr. The abstract reports: This study showed that hydrogen-rich saline ameliorates cell injury through up-regulating the expression of CBS in the hippocampus after cerebral ischemia reperfusion (I/R) in…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway.
This animal study examined Hydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Our results indicate that hydrogen-rich water has neuroprotective effects against TBI by reducing oxidative stress and activating the Nrf2 pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNeuroprotective effect of hydrogen-rich saline against neurologic damage and apoptosis in early brain injury following subarachnoid hemorrhage: possible role of the Akt/GSK3β signaling pathway.
This in vitro or cellular study examined Neuroprotective effect of hydrogen-rich saline against neurologic damage and apoptosis in early brain injury following subarachnoid hemorrhage: possible role of the Akt/GSK3β signaling pathway. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HS could attenuate neuronal apoptosis in EBI and improve the neurofunctional outcome after SAH, partially via the Akt/GSK3β pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits.
This animal study examined Hydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits. The abstract describes Rabbit model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results suggest that treatment with hydrogen in experimental SAH rabbits could alleviate brain injury via decreasing the oxidative stress injury and brain edema.…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation improves mouse neurological outcomes after cerebral ischemia/reperfusion independent of anti-necroptosis.
This animal study examined Hydrogen inhalation improves mouse neurological outcomes after cerebral ischemia/reperfusion independent of anti-necroptosis. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation; reported duration 1 hour. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline injection into the subarachnoid cavity within 2 weeks promotes recovery after acute spinal cord injury.
This animal study examined Hydrogen-rich saline injection into the subarachnoid cavity within 2 weeks promotes recovery after acute spinal cord injury. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 2 weeks. The abstract reports: Results at 24 hours, 48 hours, 1 week and 2 weeks after injury showed that hydrogen-rich saline markedly reduced cell death, inflammatory cell infiltration,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation alleviates oxidative stress in patients with post-cardiac arrest syndrome.
This uncontrolled human study examined Hydrogen gas inhalation alleviates oxidative stress in patients with post-cardiac arrest syndrome. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen saline suppresses neuronal cell apoptosis and inhibits the p38 mitogen‑activated protein kinase‑caspase‑3 signaling pathway following cerebral ischemia‑reperfusion injury.
This animal study examined Hydrogen saline suppresses neuronal cell apoptosis and inhibits the p38 mitogen‑activated protein kinase‑caspase‑3 signaling pathway following cerebral ischemia‑reperfusion injury. The abstract describes Rat model; sample size 60; hydrogen delivered as hydrogen-rich saline. The abstract reports: These results demonstrated that H2 significantly reduced the number of apoptotic cells, and the protein expression of p38 MAPK and caspase‑3, compared with the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen does not Exert Neuroprotective Effects or Improve Functional Outcomes in Rats After Intracerebral Hemorrhage.
This animal study examined Hydrogen does not Exert Neuroprotective Effects or Improve Functional Outcomes in Rats After Intracerebral Hemorrhage. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 3 days. The abstract reports: Hydrogen administration without surgery has no neuroprotective effect in the blood injection rat ICH model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury.
This animal study examined Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: We found that mHW reversed CCI-induced edema by about half, completely blocked pathological tau expression, accentuated an early increase seen in several cytokines but…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice.
This animal study examined Hydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice. The abstract describes Mouse model; sample size 1; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Activation of mast cells following intracerebral hemorrhage contributed to increase of blood-brain barrier permeability and brain edema. Hydrogen inhalation preserved blood-brain barrier disruption by…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNeuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model.
This animal study examined Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: H gas administration exerted a neuroprotective effect against early brain injury after ICH through anti-inflammatory, neuroprotective, anti-apoptotic, and antioxidative activity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation during ex vivo lung perfusion of donor lungs recovered after cardiac death.
This animal study examined Hydrogen gas inhalation during ex vivo lung perfusion of donor lungs recovered after cardiac death. The abstract describes Animal model; hydrogen delivered as hydrogen inhalation; reported duration 1 hour. The abstract reports: Hydrogen gas inhalation during EVLP improved donation after cardiac death lung function via reduction of inflammation and apoptosis, and this effect persisted after LTx. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombination of Hydrogen Inhalation and Hypothermic Temperature Control After Out-of-Hospital Cardiac Arrest: A Post hoc Analysis of the Efficacy of Inhaled Hydrogen on Neurologic Outcome Following Brain Ischemia During PostCardiac Arrest Care II Trial.
This randomized controlled trial examined Combination of Hydrogen Inhalation and Hypothermic Temperature Control After Out-of-Hospital Cardiac Arrest: A Post hoc Analysis of the Efficacy of Inhaled Hydrogen on Neurologic Outcome Following Brain Ischemia During PostCardiac Arrest Care II Trial. The abstract describes Human participants; sample size 39; hydrogen delivered as hydrogen inhalation. The abstract reports: The Efficacy of Inhaled Hydrogen on Neurologic Outcome Following Brain Ischemia During Post-Cardiac Arrest Care (HYBRID) II trial (jRCTs031180352) suggested that hydrogen inhalation may…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats.
This uncontrolled human study examined Hydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Our results demonstrated that TBI-challenged rats exhibited significant brain injuries that were characterized by decreased survival rate and increased BBB permeability, brain edema, and…. This is an automated editorial draft based on the abstract and requires source review before publication.
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