Protective effects of molecular hydrogen on lung injury from lung transplantation

This narrative review examined Protective effects of molecular hydrogen on lung injury from lung transplantation. The abstract describes Published literature review; hydrogen delivered as hydrogen water and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The reviewed studies showed that H improved the outcomes of lung transplantation by decreasing oxidative stress and inflammation at the donor and recipient phases. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas (XEN) inhalation ameliorates airway inflammation in asthma and COPD patients.

This observational study examined Hydrogen gas (XEN) inhalation ameliorates airway inflammation in asthma and COPD patients. The abstract describes Human participants; sample size 10; hydrogen delivered as hydrogen inhalation; reported duration 45 min. The abstract reports: A single inhalation of hydrogen for 45 min attenuated inflammatory status in airways in patients with asthma and COPD. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of a hydrogen-rich solution during cold ischemia in rat lung transplantation.

This animal study examined Protective effects of a hydrogen-rich solution during cold ischemia in rat lung transplantation. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: The use of a hydrogen-rich preservation solution attenuates ischemia-reperfusion injury in rat lungs during cold ischemia through antioxidant and anti-inflammatory effects. This is an automated editorial draft based on the abstract and requires source review before publication.

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Maternal molecular hydrogen treatment attenuates lipopolysaccharide-induced rat fetal lung injury.

This animal study examined Maternal molecular hydrogen treatment attenuates lipopolysaccharide-induced rat fetal lung injury. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen is a potential protective agent in the management of acute lung injury.

This uncontrolled human study examined Molecular hydrogen is a potential protective agent in the management of acute lung injury. The abstract describes Human participants. The abstract reports: Several studies have demonstrated the preventive and therapeutic effects of molecular hydrogen in the various diseases. This is an automated editorial draft based on the abstract and requires source review before publication.

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Saturated hydrogen saline protects the lung against oxygen toxicity.

This animal study examined Saturated hydrogen saline protects the lung against oxygen toxicity. The abstract describes Mouse model; hydrogen delivered as hydrogen water and hydrogen-rich saline. The abstract reports: The light microscope findings showed that saturated hydrogen saline reduced the impairment when compared with the saline group: Saturated hydrogen saline decreased lung edema,…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo.

This uncontrolled human study examined Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: We recently demonstrated that inhaled hydrogen reduced transplant-induced lung injury and induced heme oxygenase (HO)-1. This is an automated editorial draft based on the abstract and requires source review before publication.

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Attenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2 % hydrogen gas inhalation: A potential therapeutic strategy for geriatric inflammation and survival.

This animal study examined Attenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2 % hydrogen gas inhalation: A potential therapeutic strategy for geriatric inflammation and survival. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The study highlights that continuous inhalation of hydrogen gas at a 2 % concentration for 24 h can be a potent intervention in the geriatric population…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Immersing lungs in hydrogen-rich saline attenuates lung ischaemia-reperfusion injury.

This animal study examined Immersing lungs in hydrogen-rich saline attenuates lung ischaemia-reperfusion injury. The abstract describes Rat model; sample size 3; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Immersing lungs in hydrogen-rich saline delivered hydrogen into the lung and consequently attenuated lung IRI. Hydrogen-rich solution appears to be a promising approach to…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Itraq-Based Quantitative Proteomic Analysis of Lungs in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment.

This uncontrolled human study examined Itraq-Based Quantitative Proteomic Analysis of Lungs in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment. The abstract describes Human participants. The abstract reports: Functional enrichment analysis showed that H2-related differential proteins could be related to muscle contraction, oxygen transport, protein synthesis, collagen barrier membranes, cell adhesion, and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhalation reduced epithelial apoptosis in ventilator-induced lung injury via a mechanism involving nuclear factor-kappa B activation.

This animal study examined Hydrogen inhalation reduced epithelial apoptosis in ventilator-induced lung injury via a mechanism involving nuclear factor-kappa B activation. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: We recently demonstrated the inhalation of hydrogen gas, a novel medical therapeutic gas, ameliorates ventilator-induced lung injury (VILI); however, the molecular mechanisms by which…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen protects lung from hypoxia/re-oxygenation injury by reducing hydroxyl radical production and inhibiting inflammatory responses.

This animal study examined Hydrogen protects lung from hypoxia/re-oxygenation injury by reducing hydroxyl radical production and inhibiting inflammatory responses. The abstract describes Mouse model. The abstract reports: We found that H/R-induced injury in our mouse model was associated with production of hydroxyl radicals as well as increased levels of colony-stimulating factors…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of hydrogen-rich saline treatment on polymicrobial sepsis.

This animal study examined Effects of hydrogen-rich saline treatment on polymicrobial sepsis. The abstract describes Rat model; sample size 8; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS has potential protective effects against sepsis by decreasing proinflammatory responses, oxidative stress, and apoptosis in a rat model of polymicrobial sepsis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline provides protection against hyperoxic lung injury.

This animal study examined Hydrogen-rich saline provides protection against hyperoxic lung injury. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results of this study demonstrate that hydrogen-rich saline ameliorated hyperoxia-induced acute lung injury by reducing oxidative stress and inflammatory cascades in lung tissue. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline protects against acute lung injury induced by extensive burn in rat model.

This animal study examined Hydrogen-rich saline protects against acute lung injury induced by extensive burn in rat model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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