Hydrogen attenuates radiation-induced intestinal damage by reducing oxidative stress and inflammatory response.

This animal study examined Hydrogen attenuates radiation-induced intestinal damage by reducing oxidative stress and inflammatory response. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: In the animal experiment, we demonstrated that hydrogen-rich saline significantly reduced radiation-induced intestinal mucosal damage, improved intestinal function, and increased the survival rate. This is an automated editorial draft based on the abstract and requires source review before publication.

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Comprehensive brain tissue metabolomics and biological network technology to decipher the mechanism of hydrogen-rich water on Radiation-induced cognitive impairment in rats.

This animal study examined Comprehensive brain tissue metabolomics and biological network technology to decipher the mechanism of hydrogen-rich water on Radiation-induced cognitive impairment in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Our study has systematically elucidated the molecular mechanism of HRW against ionizing radiation, which can be mediated by modulating targets, pathways and metabolite levels.…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effect of Hydrogen-Rich Water on Radiation-Induced Cognitive Dysfunction in Rats

This animal study examined Effect of Hydrogen-Rich Water on Radiation-Induced Cognitive Dysfunction in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Compared to the radiation treated group, the radiation-HRW treated group showed significantly decreased escape latency ( < 0.05), but increased retention time, swimming distance…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Drinking Hydrogen-Rich Water Alleviates Chemotherapy-Induced Neuropathic Pain Through the Regulation of Gut Microbiota.

This uncontrolled human study examined Drinking Hydrogen-Rich Water Alleviates Chemotherapy-Induced Neuropathic Pain Through the Regulation of Gut Microbiota. The abstract describes Human participants; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: Hydrogen-rich water may alleviate CINP by affecting the diversity and structure of the gut microbiota, and then the LPS-TLR4 pathway, which provides a direction…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Nephroprotective effect of electrolyzed reduced water against cisplatin-induced kidney toxicity and oxidative damage in mice.

This animal study examined Nephroprotective effect of electrolyzed reduced water against cisplatin-induced kidney toxicity and oxidative damage in mice. The abstract describes Mouse model; reported duration 28 days. The abstract reports: ERW exhibits potent nephroprotective effects on cisplatin-induced kidney damage in mice, likely due to both the increase in antioxidant-defense system activity and the inhibition…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Water Ameliorates Total Body Irradiation-Induced Hematopoietic Stem Cell Injury by Reducing Hydroxyl Radical.

This animal study examined Hydrogen-Rich Water Ameliorates Total Body Irradiation-Induced Hematopoietic Stem Cell Injury by Reducing Hydroxyl Radical. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: The results indicated that HW alleviated TBI-induced HSC injury with respect to cell number alteration and to the self-renewal and differentiation of HSCs. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline protects against ultraviolet B radiation injury in rats.

This animal study examined Hydrogen-rich saline protects against ultraviolet B radiation injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effect of inhalation of hydrogen gas on radiation-induced dermatitis and skin injury in rats.

This animal study examined Protective effect of inhalation of hydrogen gas on radiation-induced dermatitis and skin injury in rats. The abstract describes Rat model. The abstract reports: Staining with terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) and 8-hydroxy-2(')-deoxyguanosine (8-OHdG) showed that the proportion of apoptotic keratinocytes and the level of staining…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline attenuates radiation-induced male germ cell loss in mice through reducing hydroxyl radicals.

This animal study examined Hydrogen-rich saline attenuates radiation-induced male germ cell loss in mice through reducing hydroxyl radicals. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Our recent studies suggest that H2 (hydrogen) has a potential as a novel radioprotector without known toxic side effects. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen protects rats from dermatitis caused by local radiation.

This uncontrolled human study examined Hydrogen protects rats from dermatitis caused by local radiation. The abstract describes Human participants; hydrogen delivered as injected or infused hydrogen. The abstract reports: These results suggest that hydrogen has a positive effect on acute radiodermatitis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen and radiation protection

This randomized controlled trial examined Molecular hydrogen and radiation protection. The abstract describes Human participants. The abstract reports: A randomised, placebo-controlled investigation also showed consumption of H(2) can improve the quality of life of patients treated with radiotherapy for liver tumours. This is an automated editorial draft based on the abstract and requires source review before publication.

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Regulation of microRNAs by molecular hydrogen contributes to the prevention of radiation-induced damage in the rat myocardium.

This animal study examined Regulation of microRNAs by molecular hydrogen contributes to the prevention of radiation-induced damage in the rat myocardium. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that the levels of malondialdehyde (MDA) and tumor necrosis factor alpha (TNF-α) increased in the rat myocardium after irradiation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen protects human lymphocyte AHH-1 cells against 12C6+ heavy ion radiation.

This in vitro or cellular study examined Molecular hydrogen protects human lymphocyte AHH-1 cells against 12C6+ heavy ion radiation. The abstract describes Lymphocyte cell model. The abstract reports: In conclusion, these data showed that H(2) attenuated (12)C(6+) radiation-induced cell apoptosis through reducing the ROS level and modulating apoptotic molecules, thus indicating the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress.

This animal study examined Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress. The abstract describes Mouse model. The abstract reports: Within 1 wk after whole thorax irradiation, immunohistochemistry and immunoblotting showed that H(2) treatment reduced oxidative stress and apoptosis, measures of acute damage, in…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effect of hydrogen-rich saline against radiation-induced immune dysfunction.

This animal study examined Protective effect of hydrogen-rich saline against radiation-induced immune dysfunction. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Recent studies showed that hydrogen can be used as an effective radioprotective agent through scavenging free radicals. This is an automated editorial draft based on the abstract and requires source review before publication.

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