Pilot study of H2 therapy in Parkinson’s disease: A randomized double‐blind placebo‐controlled trial
This randomized controlled trial examined Pilot study of H2 therapy in Parkinson’s disease: A randomized double‐blind placebo‐controlled trial. The abstract describes Human participants; sample size 9; reported duration 48 weeks. The abstract reports: The results indicated that drinking H₂-water was safe and well tolerated, and a significant improvement in total UPDRS scores for patients in the H₂-water…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas elevates urinary 8-hydroxy-2′-deoxyguanine in Parkinson’s disease.
This randomized controlled trial examined Inhalation of hydrogen gas elevates urinary 8-hydroxy-2′-deoxyguanine in Parkinson’s disease. The abstract describes Human participants; sample size 20; hydrogen delivered as hydrogen water; reported duration 10 minutes. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease.
This animal study examined Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease. The abstract describes Mouse model. The abstract reports: The concentration-dependency of H(2) showed that H(2) as low as 0.08 ppm had almost the same effect as saturated H(2) water (1.5 ppm). This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRealizing brain therapy with “smart medicine”: mechanism and case report of molecular hydrogen inhalation for Parkinson’s disease.
This case report or case series examined Realizing brain therapy with “smart medicine”: mechanism and case report of molecular hydrogen inhalation for Parkinson’s disease. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 35 years. The abstract reports: Fox Foundation has been funding research on Parkinson's disease for 35 years, but has yet to find a cure. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRole and mechanism of molecular hydrogen in the treatment of Parkinson’s diseases.
This narrative review examined Role and mechanism of molecular hydrogen in the treatment of Parkinson’s diseases. The abstract describes Published literature review. The abstract reports: While preclinical studies demonstrate promising results, clinical trials conducted thus far have yielded mixed outcomes, with some trials reporting limited or no therapeutic benefit. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreComplexity of Stomach-Brain Interaction Induced by Molecular Hydrogen in Parkinson’s Disease Model Mice.
This animal study examined Complexity of Stomach-Brain Interaction Induced by Molecular Hydrogen in Parkinson’s Disease Model Mice. The abstract describes Mouse model. The abstract reports: The protective effect of H water was still observed in the vagotomized mice in substantia nigra, suggesting that stimulation of vagal afferent nerves is…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen gas inhalation on L-DOPA-induced dyskinesia.
This uncontrolled human study examined Effects of hydrogen gas inhalation on L-DOPA-induced dyskinesia. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreChronic hydrogen-rich saline treatment reduces oxidative stress and attenuates left ventricular hypertrophy in spontaneous hypertensive rats.
This uncontrolled human study examined Chronic hydrogen-rich saline treatment reduces oxidative stress and attenuates left ventricular hypertrophy in spontaneous hypertensive rats. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline; reported duration 3 months. The abstract reports: Recently, it has been demonstrated that hydrogen, as a novel antioxidant, can selectively reduce hydroxyl radicals and peroxynitrite anion to exert therapeutic antioxidant activity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of concomitant use of hydrogen water and photobiomodulation on Parkinson disease: A pilot study.
This uncontrolled human study examined Effects of concomitant use of hydrogen water and photobiomodulation on Parkinson disease: A pilot study. The abstract describes Human participants; sample size 18; hydrogen delivered as hydrogen water. The abstract reports: This novel, proof-of-concept study demonstrated that PBM+H2 therapy is safe and reduces disease severity. A larger-scaled clinical trial is warranted to completely investigate the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Water Ameliorates Murine Chronic Graft-versus-Host Disease through Antioxidation.
This animal study examined Hydrogen-Rich Water Ameliorates Murine Chronic Graft-versus-Host Disease through Antioxidation. The abstract describes Mouse model; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: Hydrogen gas (H) has been demonstrated that has antioxidative, anti-inflammatory, and antifibrosis effects. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEmerging mechanisms and novel applications of hydrogen gas therapy.
This narrative review examined Emerging mechanisms and novel applications of hydrogen gas therapy. The abstract describes Published literature review; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen suppresses oxidative stress by inhibiting the p38 MAPK signaling pathway in preeclampsia.
This animal study examined Hydrogen suppresses oxidative stress by inhibiting the p38 MAPK signaling pathway in preeclampsia. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: It was found that hydrogen-rich saline (LH group) decreased placental MDA, proteinuria, TNF-α, and IL-1β levels in the placental tissues compared with the L…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreElectrochemically reduced water exerts superior reactive oxygen species scavenging activity in HT1080 cells than the equivalent level of hydrogen-dissolved water
This in vitro or cellular study examined Electrochemically reduced water exerts superior reactive oxygen species scavenging activity in HT1080 cells than the equivalent level of hydrogen-dissolved water. The abstract describes HT1080 cell model. The abstract reports: ERW has reactive oxygen species (ROS)-scavenging activity and recent studies demonstrated that hydrogen-dissolved water exhibits ROS-scavenging activity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis.
This animal study examined Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis. The abstract describes Rabbit model; hydrogen delivered as injected or infused hydrogen. The abstract reports: These results suggested that molecular hydrogen prevents steroid-induced osteonecrosis in rabbits by suppressing oxidative injury, vascular injury and apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Water and Lactulose Protect Against Growth Suppression and Oxidative Stress in Female Piglets Fed Toxins Contaminated Diets.
This animal study examined Hydrogen-Rich Water and Lactulose Protect Against Growth Suppression and Oxidative Stress in Female Piglets Fed Toxins Contaminated Diets. The abstract describes Porcine model; hydrogen delivered as hydrogen water; reported duration 25 days. The abstract reports: Results showed that both HRW and LAC treatments significantly attenuated the reduction of average daily gain (ADG) and average daily feed intake (ADFI) caused…. This is an automated editorial draft based on the abstract and requires source review before publication.
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