Hydrogen-rich saline attenuates eosinophil activation in a guinea pig model of allergic rhinitis via reducing oxidative stress
This animal study examined Hydrogen-rich saline attenuates eosinophil activation in a guinea pig model of allergic rhinitis via reducing oxidative stress. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: HRS may play a protective role in attenuating allergic inflammation, and suppressing the increase and activation of eosinophils in AR possibly through antioxidation effect…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model.
This uncontrolled human study examined Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model. The abstract describes Human participants; reported duration 60 min. The abstract reports: Recently, it has been suggested that hydrogen gas (H2) exerts a therapeutic antioxidant activity by selectively reducing hydroxyl radical (•OH, the most cytotoxic reactive…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of molecular hydrogen on uterine inflammation during preterm labour.
This animal study examined Effect of molecular hydrogen on uterine inflammation during preterm labour. The abstract describes Mouse model. The abstract reports: Our previous studies demonstrated that molecular hydrogen (H), an anti-inflammatory agent, prevented inflammation-induced impairment in foetal brain and lung tissues in lipopolysaccharide (LPS)-induced rodent…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombating Oxidative Stress and Inflammation in COVID-19 by Molecular Hydrogen Therapy: Mechanisms and Perspectives.
This narrative review examined Combating Oxidative Stress and Inflammation in COVID-19 by Molecular Hydrogen Therapy: Mechanisms and Perspectives. The abstract describes Published literature review. The abstract reports: This situation results in impaired gas exchange, hypoxia, and other sequelae that lead to multisystem organ failure and death. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreH2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain.
This animal study examined H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain. The abstract describes Rat model. The abstract reports: We found that H2 clearly inhibited hyperalgesia and allodynia in neuropathic pain and also attenuated the pro-inflammatory cytokines TNF-α, IL-1β, and high-mobility group box…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreIn Situ Nanoreactor for Photosynthesizing H Gas To Mitigate Oxidative Stress in Tissue Inflammation.
This animal study examined In Situ Nanoreactor for Photosynthesizing H Gas To Mitigate Oxidative Stress in Tissue Inflammation. The abstract describes Mouse model. The abstract reports: Experimental results indicate that the Lip NR system that can photosynthesize H gas has great potential for mitigating oxidative stress in tissue inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice.
This animal study examined The immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice. The abstract describes Mouse model. The abstract reports: In the case of infected groups, the group fed ERW (ERW+E. hortense group) showed the result that IL-4, IL-5, IL-10 and Ig A expression…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAnti-inflammation effects of hydrogen saline in LPS activated macrophages and carrageenan induced paw oedema.
This in vitro or cellular study examined Anti-inflammation effects of hydrogen saline in LPS activated macrophages and carrageenan induced paw oedema. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: As a more convenient way than inhaling H2, hydrogen saline exhibits a protective effect against inflammation and it might provide a novel therapeutic approach…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen increases resilience to stress in mice.
This animal study examined Molecular hydrogen increases resilience to stress in mice. The abstract describes Mouse model; hydrogen delivered as oxyhydrogen. The abstract reports: The results showed that repeated inhalation of hydrogen-oxygen mixed gas [67%:33% (V/V)] significantly decreased both the acute and chronic stress-induced depressive- and anxiety-like behaviors…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators.
This in vitro or cellular study examined Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators. The abstract describes Cell culture / in vitro model. The abstract reports: We previously showed that H2 acts as a novel antioxidant to protect cells against oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model
This uncontrolled human study examined Combination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model. The abstract describes Human participants. The abstract reports: The results showed that the inhalation of H (2%) or hyperoxia (98%) alone improved the 14-day survival rate of ZY-challenged mice from 20 to…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreImpact of molecular hydrogen treatments on the innate immune activity and survival of zebrafish (Danio rerio) challenged with Aeromonas hydrophila.
This animal study examined Impact of molecular hydrogen treatments on the innate immune activity and survival of zebrafish (Danio rerio) challenged with Aeromonas hydrophila. The abstract describes Zebrafish model; hydrogen delivered as hydrogen water. The abstract reports: We have found an increased survival rate of bacteria-challenged zebrafish subjected to the HRW immersion treatment. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate.
This animal study examined Hydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHeme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages.
This in vitro or cellular study examined Heme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages. The abstract describes Cell culture / in vitro model. The abstract reports: Molecular hydrogen exerts a regulating role in the release of pro- and anti-inflammatory cytokines in LPS-stimulated macrophages, and this effect is at least partly…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline resuscitation alleviates inflammation induced by severe burn with delayed resuscitation.
This animal study examined Hydrogen-rich saline resuscitation alleviates inflammation induced by severe burn with delayed resuscitation. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: We found that resuscitation by hydrogen-rich saline alleviated inflammation significantly. This is an automated editorial draft based on the abstract and requires source review before publication.
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