Recent progress toward hydrogen medicine: potential of molecular hydrogen for preventive and therapeutic applications.

This narrative review examined Recent progress toward hydrogen medicine: potential of molecular hydrogen for preventive and therapeutic applications. The abstract describes Published literature review; hydrogen delivered as hydrogen water and hydrogen-rich saline and hydrogen bath. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen rich water on the intestinal ischemia/reperfusion injury due to intestinal intussusception in a rat model.

This animal study examined Protective effects of hydrogen rich water on the intestinal ischemia/reperfusion injury due to intestinal intussusception in a rat model. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 15 minutes. The abstract reports: Hematoxylin-eosin staining showed the intestinal mucosa was significantly damaged in I/R + saline group, which was markedly attenuated after HRW treatment. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline protects against intestinal ischemia/reperfusion injury in rats.

This animal study examined Hydrogen-rich saline protects against intestinal ischemia/reperfusion injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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Luminal injection of hydrogen-rich solution attenuates intestinal ischemia-reperfusion injury in rats.

This animal study examined Luminal injection of hydrogen-rich solution attenuates intestinal ischemia-reperfusion injury in rats. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen; reported duration 90 min. The abstract reports: Luminal injection of hydrogen-rich solution can reduce oxidative stress and consequently ameliorate ischemic-reperfusion injury. Hydrogen-containing solution can be a novel and promising luminal preservation…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury.

This animal study examined Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen treatment resulted in significantly improved gastrointestinal transit, as well as jejunal smooth muscle contractility in response to bethanechol. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-enriched preservation protects the isogeneic intestinal graft and amends recipient gastric function during transplantation.

This animal study examined Hydrogen-enriched preservation protects the isogeneic intestinal graft and amends recipient gastric function during transplantation. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Graft preloading with hydrogen demonstrated superior morphologic and functional graft protection in rodent intestinal transplantation, ultimately facilitating recipient survival. Antioxidant capacity and muscularis heme…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen-rich saline on necrotizing enterocolitis in neonatal rats.

This animal study examined Protective effects of hydrogen-rich saline on necrotizing enterocolitis in neonatal rats. The abstract describes Rat model; sample size 11; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS showed beneficial effects on neonatal rats with NEC via decreasing oxidative stress, increasing antioxidant capacity, suppressing inflammation, and preserving mucosal integrity. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen-rich saline on ulcerative colitis rat model.

This animal study examined Protective effects of hydrogen-rich saline on ulcerative colitis rat model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Antioxidative hydrogen-rich saline effectively protected the rats from UC, which might be, at least in part, because of inhibition of vascular endothelial growth factor. This is an automated editorial draft based on the abstract and requires source review before publication.

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Daily ingestion of alkaline electrolyzed water containing hydrogen influences human health, including gastrointestinal symptoms.

This randomized controlled trial examined Daily ingestion of alkaline electrolyzed water containing hydrogen influences human health, including gastrointestinal symptoms. The abstract describes Human participants. The abstract reports: And for the patients with gastrointestinal symptoms, drinking AEW has been found to be effective in relieving gastrointestinal symptoms. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effect of molecular hydrogen saturated alkaline electrolyzed water on disuse muscle atrophy in gastrocnemius muscle.

This animal study examined Effect of molecular hydrogen saturated alkaline electrolyzed water on disuse muscle atrophy in gastrocnemius muscle. The abstract describes Rat model; reported duration 3 weeks. The abstract reports: We showed that 8-OHdG, but not MDA, significantly increased by 149% and 145% in HU-NW and HU-AEW, respectively, when compared with CONT. This is an automated editorial draft based on the abstract and requires source review before publication.

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MicroRNA files in the prevention of intestinal ischemia/reperfusion injury by hydrogen rich saline.

This animal study examined MicroRNA files in the prevention of intestinal ischemia/reperfusion injury by hydrogen rich saline. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Collectively, miR-199a-3p may serve a key role in the anti-apoptotic mechanism of HRS that contributes to its protection of the intestine against I/R injury. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice.

This animal study examined Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice. The abstract describes Mouse model; reported duration 4 weeks. The abstract reports: Results of 16S rRNA gene sequencing analyses showed that the relative abundances of 20 taxa differed significantly in AEW-administered mice. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen suppresses gut inflammation and pyroptosis in ulcerative colitis through promoting PKM2 lactylation to block NLRP3 inflammasome activation.

This uncontrolled human study examined Molecular hydrogen suppresses gut inflammation and pyroptosis in ulcerative colitis through promoting PKM2 lactylation to block NLRP3 inflammasome activation. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Molecular hydrogen can promote PKM2 lactylation to restrain NLRP3 inflammasome-mediated pyroptosis and inflammation, thus ameliorating UC progression. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water protects against inflammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression.

This animal study examined Hydrogen-rich water protects against inflammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: The histological study demonstrated milder inflammation in the DSS + HRW group, which was similar to normal inflammatory levels, and the macroscopic and microcosmic…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective role of hydrogen-rich water on aspirin-induced gastric mucosal damage in rats.

This animal study examined Protective role of hydrogen-rich water on aspirin-induced gastric mucosal damage in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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