High concentration of hydrogen gas alleviates Lipopolysaccharide-induced lung injury via activating Nrf2 signaling pathway in mice.
This animal study examined High concentration of hydrogen gas alleviates Lipopolysaccharide-induced lung injury via activating Nrf2 signaling pathway in mice. The abstract describes Mouse model. The abstract reports: HCH can effectively alleviate LPS-induced ALI, which may be related to activation of Nrf2 signaling pathway and inhibition of inflammatory response and cell apoptosis…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe Benefit of Hydrogen Gas as an Adjunctive Therapy for Chronic Obstructive Pulmonary Disease
This uncontrolled human study examined The Benefit of Hydrogen Gas as an Adjunctive Therapy for Chronic Obstructive Pulmonary Disease. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 30 min. The abstract reports: Recent studies suggest that hydrogen gas possesses anti-inflammatory, antioxidant, and anti-apoptotic properties. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response in mice.
This animal study examined Hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response most probably through the TLR4-NF-κB pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe effects of inhaling hydrogen gas on macrophage polarization, fibrosis, and lung function in mice with bleomycin-induced lung injury.
This animal study examined The effects of inhaling hydrogen gas on macrophage polarization, fibrosis, and lung function in mice with bleomycin-induced lung injury. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results suggest that hydrogen inhalation inhibits the deterioration of respiratory physiological function and alveolar fibrosis in this model of lung injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas (XEN) inhalation ameliorates airway inflammation in asthma and COPD patients.
This observational study examined Hydrogen gas (XEN) inhalation ameliorates airway inflammation in asthma and COPD patients. The abstract describes Human participants; sample size 10; hydrogen delivered as hydrogen inhalation; reported duration 45 min. The abstract reports: A single inhalation of hydrogen for 45 min attenuated inflammatory status in airways in patients with asthma and COPD. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo.
This uncontrolled human study examined Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: We recently demonstrated that inhaled hydrogen reduced transplant-induced lung injury and induced heme oxygenase (HO)-1. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreItraq-Based Quantitative Proteomic Analysis of Lungs in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment.
This uncontrolled human study examined Itraq-Based Quantitative Proteomic Analysis of Lungs in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment. The abstract describes Human participants. The abstract reports: Functional enrichment analysis showed that H2-related differential proteins could be related to muscle contraction, oxygen transport, protein synthesis, collagen barrier membranes, cell adhesion, and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen gas against sepsis-induced acute lung injury via regulation of mitochondrial function and dynamics.
This animal study examined Protective effects of hydrogen gas against sepsis-induced acute lung injury via regulation of mitochondrial function and dynamics. The abstract describes Mouse model. The abstract reports: Therapy with 2% H increased PaO/FiO ratios, MMP and ATP levels, RCR, complex I activity and MFN2 expression but decreased histological score and Drp1…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice.
This animal study examined Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen gas inhalation improves lung function and protects established airway inflammation in the allergic asthmatic mice model which may be associated with the inhibition…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAntioxidant Properties of Hydrogen Gas Attenuates Oxidative Stress in Airway Epithelial Cells.
This in vitro or cellular study examined Antioxidant Properties of Hydrogen Gas Attenuates Oxidative Stress in Airway Epithelial Cells. The abstract describes A549 cell model. The abstract reports: Results show that time-dependent administration of 2% H gas recovered the cells from oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effect of inhalation of hydrogen gas on radiation-induced dermatitis and skin injury in rats.
This animal study examined Protective effect of inhalation of hydrogen gas on radiation-induced dermatitis and skin injury in rats. The abstract describes Rat model. The abstract reports: Staining with terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) and 8-hydroxy-2(')-deoxyguanosine (8-OHdG) showed that the proportion of apoptotic keratinocytes and the level of staining…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas elevates urinary 8-hydroxy-2′-deoxyguanine in Parkinson’s disease.
This randomized controlled trial examined Inhalation of hydrogen gas elevates urinary 8-hydroxy-2′-deoxyguanine in Parkinson’s disease. The abstract describes Human participants; sample size 20; hydrogen delivered as hydrogen water; reported duration 10 minutes. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEmerging mechanisms and novel applications of hydrogen gas therapy.
This narrative review examined Emerging mechanisms and novel applications of hydrogen gas therapy. The abstract describes Published literature review; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates oxygen toxicity by reducing hydroxyl radical levels in PC12 cells.
This in vitro or cellular study examined Hydrogen gas alleviates oxygen toxicity by reducing hydroxyl radical levels in PC12 cells. The abstract describes PC12 cell model. The abstract reports: The data showed that H2 promoted the cell viability and inhibited the damage in the cell and mitochondria membrane, reduced the levels of lipid…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe effect of hydrogen gas on the oxidative stress response in adipose tissue.
This uncontrolled human study examined The effect of hydrogen gas on the oxidative stress response in adipose tissue. The abstract describes Human participants. The abstract reports: The immunostaining results showed that HO-1 and Nrf2 expression levels were significantly decreased in the hydrogenated group, whereas SOD expression levels increased, but did…. This is an automated editorial draft based on the abstract and requires source review before publication.
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