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The researchers observed that hydrogen treatment partially reversed the increase in lung tissue density and reduced pulmonary inflammation. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn a laboratory model, the subsequent in vitro experiments showed that H₂ treatment inhibited the phosphorylation of extracellular signal-regulated kinase (ERK), c-jun N-terminal kinase (JNK), and p38 MAPK,…
Read ArticleIn Sprague Dawley rats, the study examined whether hydrogen-rich water could protect skeletal muscle from eccentric-exercise injury and explored the underlying mechanisms. These results are preclinical and suggest…
Read ArticleThe researchers found that the beneficial effects of hydrogen-rich saline treatment were associated with decreased levels of oxidative products (8-iso-prostaglandin F2α and malondialdehyde) and inflammatory cytokines (tumor necrosis…
Read ArticleIn an animal model, cUMS induced elevation in IL-1β protein levels in the hippocampus, and the cortex was significantly attenuated after 4 weeks of feeding the mice hydrogen-rich…
Read ArticleIn male Wistar rats, during mild SI, H₂ reduced plasma surges of proinflammatory cytokines (TNF-α and IL-6) while caused an increase in plasma IL-10 (anti-inflammatory cytokine) and prevented…
Read ArticleIn Sprague Dawley rats, the study examined whether hydrogen-rich water could protect skeletal muscle from eccentric-exercise injury and explored the underlying mechanisms. These results are preclinical and suggest…
Read ArticleIn rats, the data showed that the spatial recognition memory and fear memory of the rats treated with sevoflurane decreased compared with the control, and the cognitive function…
Read ArticleIn rats, compared with PHN group,the rats in the PHN-H₂ group and PHN-H₂-Rap group showed increased PWT,decreased levels of TNF-α,IL-1β and IL-6,further up-regulated expressions of LC3 and beclin…
Read ArticleIn an animal model, the mechanism by which hydrogen gas alleviates TBI may be related to inhibiting NLRP3 inflammasomes in the cerebral cortex of rats. These preclinical findings…
Read ArticleIn The mRNA levels of ANP and BNP were examined by PCR in vitro, lPS induced cardiac dysfunction; hydrogen therapy improved cardiac function after LPS challenge. The authors…
Read ArticleThis preclinical study evaluated hydrogen-rich saline in rats. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to…
Read ArticleThis publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
Read ArticleIn rats, the administration of HRS resulted in a significant decrease in the brain injury, together with lower production of IL-1β, TNF-α, 8-OHdG and MDA as well as…
Read ArticleHydrogen-rich saline reduced renal inflammatory-cytokine expression and improved several kidney-injury measures in severely burned rats. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition…
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