Attenuation of cigarette smoke-induced airway mucus production by hydrogen-rich saline in rats.
This animal study examined Attenuation of cigarette smoke-induced airway mucus production by hydrogen-rich saline in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline pretreatment ameliorated CS-induced airway mucus production and airway epithelium damage in rats. The protective role of hydrogen on CS-exposed rat lungs was…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-enriched water eliminates fine particles from the lungs and blood by enhancing phagocytic activity.
This animal study examined Hydrogen-enriched water eliminates fine particles from the lungs and blood by enhancing phagocytic activity. The abstract describes Mouse model; reported duration 10 weeks. The abstract reports: Collectively, the results indicate that HW not only effectively eliminated PM from the lungs and blood by enhancing phagocytic activity, but also attenuated the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model
This animal study examined Hydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model. The abstract describes Rat model; hydrogen delivered as hydrogen water and hydrogen inhalation. The abstract reports: These results suggest that hydrogen inhalation slows the development of COPD-like lung disease in a cigarette smoke-induced rat model. Higher concentrations of hydrogen may…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice.
This animal study examined Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen gas inhalation improves lung function and protects established airway inflammation in the allergic asthmatic mice model which may be associated with the inhibition…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen in the Treatment of Respiratory Diseases.
Molecular hydrogen is gaining increasing attention as an antioxidant, anti-inflammatory, and antiapoptotic agent. Once considered an inert gas, it reveals current therapeutic potential among others in inflammatory diseases, cancer, and sports medicine, among others. The present review aims to provide a consistent summary of the findings of the last twenty years on the use of molecular hydrogen in major respiratory diseases, including allergies, asthma, COPD, pulmonary fibrosis, lung injury of various origins, as well as cancer and infections of the respiratory tract.
Read MoreCan Hydrogen Water Enhance Oxygen Saturation in Patients with Chronic Lung Disease? A Non-Randomized, Observational Pilot Study.
Recently, chronic lung diseases have been found to be associated with marked inflammation and oxidative stress, which leads to fibrosis in the lungs and chronic respiratory failure. This study aims to determine if hydrogen-rich water (HRW) can enhance oxygen saturation among patients with chronic lung diseases. Ten patients with chronic lung diseases due to COPD ( = 7), bronchial asthma ( = 2), and tuberculosis of the lung ( = 1) with oxygen saturation of 90-95% were provided high-concentration (>5 mM) HRW using H-producing tablets for 4 weeks.
Read MoreHydrogen gas inhalation enhances alveolar macrophage phagocytosis in an ovalbumin-induced asthma model
This animal study examined Hydrogen gas inhalation enhances alveolar macrophage phagocytosis in an ovalbumin-induced asthma model. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Our findings demonstrated that hydrogen gas inhalation enhanced alveolar macrophage phagocytosis in OVA-induced asthmatic mice, which may be associated with the antioxidant effects of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAntioxidant Properties of Hydrogen Gas Attenuates Oxidative Stress in Airway Epithelial Cells.
This in vitro or cellular study examined Antioxidant Properties of Hydrogen Gas Attenuates Oxidative Stress in Airway Epithelial Cells. The abstract describes A549 cell model. The abstract reports: Results show that time-dependent administration of 2% H gas recovered the cells from oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen alleviates cell damage and acute lung injury in sepsis via PINK1/Parkin-mediated mitophagy
This animal study examined Hydrogen alleviates cell damage and acute lung injury in sepsis via PINK1/Parkin-mediated mitophagy. The abstract describes Mouse model. The abstract reports: These results suggest that PINK1-mediated mitophagy plays a key role in the protective effects of hydrogen against cell injury in LPS-induced inflammation and CLP-induced…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHigh concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner
This animal study examined High concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Results showed that 66.7 % hydrogen alleviated lung pathological changes and pulmonary edema caused by LPS, and reduced the degree of ALI by inhibiting…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation attenuated bleomycin‐induced pulmonary fibrosis by inhibiting transforming growth factor‐β1 and relevant oxidative stress and epithelial‐to‐mesenchymal transition
This uncontrolled human study examined Hydrogen inhalation attenuated bleomycin‐induced pulmonary fibrosis by inhibiting transforming growth factor‐β1 and relevant oxidative stress and epithelial‐to‐mesenchymal transition. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: • What is the central question of this study? The aim was to explore the effects and underlying mechanisms of H on bleomycin-induced pulmonary…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombination of Korean Red Ginseng Extract and Hydrogen-Rich Water Improves Spermatogenesis and Sperm Motility in Male Mice
This animal study examined Combination of Korean Red Ginseng Extract and Hydrogen-Rich Water Improves Spermatogenesis and Sperm Motility in Male Mice. The abstract describes Mouse model; sample size 10; hydrogen delivered as hydrogen water; reported duration 4 weeks. The abstract reports: HRGW increases sperm production and motility by enhancing antioxidation and stimulating spermatogenesis and sex hormone production, particularly in aged mice. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects spermatogenesis and hematopoiesis in irradiated BALB/c mice.
This animal study examined Hydrogen-rich saline protects spermatogenesis and hematopoiesis in irradiated BALB/c mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: This study suggests that hydrogen-rich saline could partially protect spermatogenesis and hematopoiesis in irradiated mice. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreLong-term treatment of hydrogen-rich saline abates testicular oxidative stress induced by nicotine in mice.
This animal study examined Long-term treatment of hydrogen-rich saline abates testicular oxidative stress induced by nicotine in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Our results first demonstrated that long-term treatment with hydrogen-rich saline attenuated testicular oxidative level and improved male reproductive function in nicotine-treated mice. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water ameliorates rat placental stress induced by water restriction.
This animal study examined Hydrogen-rich water ameliorates rat placental stress induced by water restriction. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: We demonstrated that maternal water restriction resulted in reduced urine volume and increased serum osmotic pressure, along with decreased fetus weight and crown-rump length. This is an automated editorial draft based on the abstract and requires source review before publication.
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