Hydrogen therapy may be an effective and specific novel treatment for acute graft-versus-host disease (GVHD).
This animal study examined Hydrogen therapy may be an effective and specific novel treatment for acute graft-versus-host disease (GVHD). The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Besides, the oxidation phenomena and/or the formation of free radicals have been suggested to be causally related to various haematological disorders including aGVHD. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen, a potential safeguard for graft-versus-host disease and graft ischemia-reperfusion injury?
Post-transplant complications such as graft-versus-host disease and graft ischemia-reperfusion injury are crucial challenges in transplantation. Hydrogen can act as a potential antioxidant, playing a preventive role against post-transplant complications in animal models of multiple organ transplantation. Herein, the authors review the current literature regarding the effects of hydrogen on graft ischemia-reperfusion injury and graft-versus-host disease.
Read MoreNew Approach in Translational Medicine: Effects of Electrolyzed Reduced Water (ERW) on NF-κB/iNOS Pathway in U937 Cell Line under Altered Redox State.
This in vitro or cellular study examined New Approach in Translational Medicine: Effects of Electrolyzed Reduced Water (ERW) on NF-κB/iNOS Pathway in U937 Cell Line under Altered Redox State. The abstract describes Cell culture / in vitro model. The abstract reports: Several findings indicate that ERW had the ability of a scavenger free radical, which results from hydrogen molecules with a high reducing ability and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe neuroprotective effects of electrolyzed reduced water and its model water containing molecular hydrogen and Pt nanoparticles.
This in vitro or cellular study examined The neuroprotective effects of electrolyzed reduced water and its model water containing molecular hydrogen and Pt nanoparticles. The abstract describes PC12 cell model. The abstract reports: We previously showed that ERW was capable of extending lifespan of Caenorhabditis elegans by scavenging ROS [2]. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of Molecular Hydrogen, a Rescue Treatment for Noise-Induced Hearing Loss.
This uncontrolled human study examined Inhalation of Molecular Hydrogen, a Rescue Treatment for Noise-Induced Hearing Loss. The abstract describes Human participants. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with COVID-19: A retrospective study of medical records.
This observational study examined Hydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with COVID-19: A retrospective study of medical records. The abstract describes Human participants; sample size 19; hydrogen delivered as oxyhydrogen. The abstract reports: The physiological and biochemical indexes, including immune inflammation indicators, electrolytes, myocardial enzyme profile, and functions of liver and kidney, were examined and investigated before…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen in Transplantation: Potential Applications and Therapeutic Implications.
This narrative review examined Hydrogen in Transplantation: Potential Applications and Therapeutic Implications. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePrenatal Molecular Hydrogen Administration Ameliorates Several Findings in Nitrofen-Induced Congenital Diaphragmatic Hernia.
This animal study examined Prenatal Molecular Hydrogen Administration Ameliorates Several Findings in Nitrofen-Induced Congenital Diaphragmatic Hernia. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Gasometric results (pH, pO and pCO levels) were better in the CDH + HW group than in the CDH group. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Therapy and Its Future Prospects for Ameliorating COVID-19: Clinical Applications, Efficacy, and Modality.
Molecular hydrogen is renowned as an odorless and colorless gas. The recommendations developed by China suggest that the inhalation of hydrogen molecules is currently advised in COVID-19 pneumonia treatment. The therapeutic effects of molecular hydrogens have been confirmed after numerous clinical trials and animal-model-based experiments, which have expounded that the low molecular weight of hydrogen enables it to easily diffuse and permeate through the cell membranes to produce a variety of biological impacts.
Read MoreAn LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs.
Noise-induced hearing loss (NIHL) is an increasing problem in society and accounts for a third of all cases of acquired hearing loss. NIHL is caused by formation of reactive oxygen species (ROS) in the cochlea causing oxidative stress. Hydrogen gas (H) can alleviate the damage caused by oxidative stress and can be easily administered through inhalation.
Read MoreTaurine, Coenzyme Q10, and Hydrogen Water Prevents Germanium Dioxide-Induced Mitochondrial Dysfunction and Associated Sensorineural Hearing Loss in mouse
This animal study examined Taurine, Coenzyme Q10, and Hydrogen Water Prevents Germanium Dioxide-Induced Mitochondrial Dysfunction and Associated Sensorineural Hearing Loss in mouse. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: In the current study, we showed that supplementation with germanium dioxide (GeO) in CBA/J mice resulted in SNHL due to the degeneration of the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA link between gut community metabolism and pathogenesis: molecular hydrogen-stimulated glucarate catabolism aids Salmonella virulence.
This animal study examined A link between gut community metabolism and pathogenesis: molecular hydrogen-stimulated glucarate catabolism aids Salmonella virulence. The abstract describes Mouse model. The abstract reports: Our results link a gut microbiome-produced diffusible metabolite to augmenting bacterial pathogenesis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism.
This animal study examined Molecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism. The abstract describes Mouse model. The abstract reports: The expression of might be regulated indirectly through sequential regulation by H, 4-hydroxy-2-nonenal, and Akt/FoxO1 signaling, as suggested in cultured cell experiments. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMitochondria: one of the vital hubs for molecular hydrogen’s biological functions.
As a novel antioxidant, a growing body of studies has documented the diverse biological effects of molecular hydrogen (H) in a wide range of organisms, spanning animals, plants, and microorganisms. Although several possible mechanisms have been proposed, they cannot fully explain the extensive biological effects of H. Mitochondria, known for ATP production, also play crucial roles in diverse cellular functions, including Ca signaling, regulation of reactive oxygen species (ROS) generation, apoptosis, proliferation, and lipid transport, while their dysfunction is implicated in a broad spectrum of diseases, including cardiovascular disorders, neurodegenerative…
Read MoreMolecular hydrogen inhalation modulates resting metabolism in healthy females: findings from a randomized, double-blind, placebo-controlled crossover study.
This randomized controlled trial examined Molecular hydrogen inhalation modulates resting metabolism in healthy females: findings from a randomized, double-blind, placebo-controlled crossover study. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 60 minutes. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreBlog Categories
Recent Posts
October 21, 2020
November 16, 2020
October 02, 2017