A Comprehensive Analysis of the Electrolytic Hydrogen Water Mechanism via a Feedforward Loop and its Functional Role in Intestinal Cells In Vitro

This in vitro or cellular study examined A Comprehensive Analysis of the Electrolytic Hydrogen Water Mechanism via a Feedforward Loop and its Functional Role in Intestinal Cells In Vitro. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: Highlights Identification of Novel Key Regulatory Genes Modulated by Electrolytic Hydrogen Water (EHW) Treatment: PPI network analysis demonstrated that EHW downregulates mitochondrial oxidative metabolism-related…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Electrolyzed Hydrogen Water Alleviates Abdominal Pain through Suppression of Colonic Tissue Inflammation in a Rat Model of Inflammatory Bowel Disease

This uncontrolled human study examined Electrolyzed Hydrogen Water Alleviates Abdominal Pain through Suppression of Colonic Tissue Inflammation in a Rat Model of Inflammatory Bowel Disease. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: We found that EHW significantly alleviated TNBS-induced abdominal pain and tissue inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Ameliorating Role of Hydrogen-Rich Water Against NSAID-Induced Enteropathy via Reduction of ROS and Production of Short-Chain Fatty Acids.

This animal study examined Ameliorating Role of Hydrogen-Rich Water Against NSAID-Induced Enteropathy via Reduction of ROS and Production of Short-Chain Fatty Acids. The abstract describes Mouse model; hydrogen delivered as hydrogen water; reported duration 5 days. The abstract reports: Hydrogen-rich water ameliorated NSAID-induced enteropathy, not only via direct antioxidant effects but also via anti-inflammatory effects by increasing luminal SCFAs. These results suggest that…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective Role of Hydrogen Gas on Oxidative Damage and Apoptosis in Intestinal Porcine Epithelial Cells (IPEC-J2) Induced by Deoxynivalenol: A Preliminary Study.

This in vitro or cellular study examined Protective Role of Hydrogen Gas on Oxidative Damage and Apoptosis in Intestinal Porcine Epithelial Cells (IPEC-J2) Induced by Deoxynivalenol: A Preliminary Study. The abstract describes Epithelial cell model. The abstract reports: Our results demonstrated that the 5 μM DON significantly caused cytotoxicity to IPEC-J2 cells by reducing cell viability and increasing lactate dehydrogenase release in…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Intraperitoneally administered, hydrogen-rich physiologic solution protects against postoperative ileus and is associated with reduced nitric oxide production

This animal study examined Intraperitoneally administered, hydrogen-rich physiologic solution protects against postoperative ileus and is associated with reduced nitric oxide production. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: A single intraperitoneal dose of hydrogen-rich saline ameliorates postoperative ileus by inhibiting the inflammatory response and suppressing nitric oxide production. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline protects against ischemia/reperfusion injury in grafts after pancreas transplantations by reducing oxidative stress in rats.

This animal study examined Hydrogen-rich saline protects against ischemia/reperfusion injury in grafts after pancreas transplantations by reducing oxidative stress in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Hydrogen-rich saline treatment significantly attenuated the severity of pancreatic I/R injury in rats, possibly by reducing oxidative stress and inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Recent progress toward hydrogen medicine: potential of molecular hydrogen for preventive and therapeutic applications.

This narrative review examined Recent progress toward hydrogen medicine: potential of molecular hydrogen for preventive and therapeutic applications. The abstract describes Published literature review; hydrogen delivered as hydrogen water and hydrogen-rich saline and hydrogen bath. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen rich water on the intestinal ischemia/reperfusion injury due to intestinal intussusception in a rat model.

This animal study examined Protective effects of hydrogen rich water on the intestinal ischemia/reperfusion injury due to intestinal intussusception in a rat model. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 15 minutes. The abstract reports: Hematoxylin-eosin staining showed the intestinal mucosa was significantly damaged in I/R + saline group, which was markedly attenuated after HRW treatment. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen-rich saline on necrotizing enterocolitis in neonatal rats.

This animal study examined Protective effects of hydrogen-rich saline on necrotizing enterocolitis in neonatal rats. The abstract describes Rat model; sample size 11; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS showed beneficial effects on neonatal rats with NEC via decreasing oxidative stress, increasing antioxidant capacity, suppressing inflammation, and preserving mucosal integrity. This is an automated editorial draft based on the abstract and requires source review before publication.

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Daily ingestion of alkaline electrolyzed water containing hydrogen influences human health, including gastrointestinal symptoms.

This randomized controlled trial examined Daily ingestion of alkaline electrolyzed water containing hydrogen influences human health, including gastrointestinal symptoms. The abstract describes Human participants. The abstract reports: And for the patients with gastrointestinal symptoms, drinking AEW has been found to be effective in relieving gastrointestinal symptoms. This is an automated editorial draft based on the abstract and requires source review before publication.

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MicroRNA files in the prevention of intestinal ischemia/reperfusion injury by hydrogen rich saline.

This animal study examined MicroRNA files in the prevention of intestinal ischemia/reperfusion injury by hydrogen rich saline. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Collectively, miR-199a-3p may serve a key role in the anti-apoptotic mechanism of HRS that contributes to its protection of the intestine against I/R injury. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice.

This animal study examined Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice. The abstract describes Mouse model; reported duration 4 weeks. The abstract reports: Results of 16S rRNA gene sequencing analyses showed that the relative abundances of 20 taxa differed significantly in AEW-administered mice. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water protects against inflammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression.

This animal study examined Hydrogen-rich water protects against inflammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: The histological study demonstrated milder inflammation in the DSS + HRW group, which was similar to normal inflammatory levels, and the macroscopic and microcosmic…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective role of hydrogen-rich water on aspirin-induced gastric mucosal damage in rats.

This animal study examined Protective role of hydrogen-rich water on aspirin-induced gastric mucosal damage in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhaled hydrogen ameliorates endotoxin-induced bowel dysfunction.

This uncontrolled human study examined Inhaled hydrogen ameliorates endotoxin-induced bowel dysfunction. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: This study showed the protective effects of hydrogen inhalation on LPS-induced septic ileus through inhibition of inflammation in the muscularis propria. These inhibitory effects…. This is an automated editorial draft based on the abstract and requires source review before publication.

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