Hydrogen inhalation therapy alone may not alleviate intestinal mucosal damage in NOMI without total‐layer necrosis: An experimental swine model study

This animal study examined Hydrogen inhalation therapy alone may not alleviate intestinal mucosal damage in NOMI without total‐layer necrosis: An experimental swine model study. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Although critically ill conditions can trigger NOMI, the model used in this study did not involve transmural necrosis. Under such conditions, hydrogen inhalation therapy…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas Inhalation Improved Intestinal Microbiota in Ulcerative Colitis: A Randomised Double-Blind Placebo-Controlled Trial.

This randomized controlled trial examined Hydrogen Gas Inhalation Improved Intestinal Microbiota in Ulcerative Colitis: A Randomised Double-Blind Placebo-Controlled Trial. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 8 weeks. The abstract reports: The hydrogen group showed higher α-diversity ( = 0.19), and the variation in β-diversity was markedly different, compared to the placebo group, in intestinal…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Water Mitigates LPS-Induced Chronic Intestinal Inflammatory Response in Rats via Nrf-2 and NF-κB Signaling Pathways.

This animal study examined Hydrogen-Rich Water Mitigates LPS-Induced Chronic Intestinal Inflammatory Response in Rats via Nrf-2 and NF-κB Signaling Pathways. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: The obtained results show that hydrogen-rich water significantly increased the levels of superoxide dismutase and structural proteins; activated the Nrf-2 signaling pathway; downregulated the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen is comparable to sulfasalazine as a treatment for DSS-induced colitis in mice.

This animal study examined Molecular hydrogen is comparable to sulfasalazine as a treatment for DSS-induced colitis in mice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective Effects of Hydrogen Gas on Experimental Acute Pancreatitis.

This uncontrolled human study examined Protective Effects of Hydrogen Gas on Experimental Acute Pancreatitis. The abstract describes Human participants. The abstract reports: The results revealed significant reductions in inflammation and oxidative stress both in vitro and in vivo. This is an automated editorial draft based on the abstract and requires source review before publication.

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Drinking hydrogen water improves photoreceptor structure and function in retinal degeneration 6 mice.

This animal study examined Drinking hydrogen water improves photoreceptor structure and function in retinal degeneration 6 mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Given the known contributions of oxidative stress caused by reactive oxygen species (ROS) and selective inhibition of potent ROS peroxynitrite and OH·by H gas…. This is an automated editorial draft based on the abstract and requires source review before publication.

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An Immunohistochemical Study of the Increase in Antioxidant Capacity of Corneal Epithelial Cells by Molecular Hydrogen, Leading to the Suppression of Alkali-Induced Oxidative Stress

This in vitro or cellular study examined An Immunohistochemical Study of the Increase in Antioxidant Capacity of Corneal Epithelial Cells by Molecular Hydrogen, Leading to the Suppression of Alkali-Induced Oxidative Stress. The abstract describes Epithelial cell model. The abstract reports: The results obtained with immunohistochemistry and pachymetry showed that in the corneas of H-pretreated eyes, slight oxidative stress appeared followed by an increased expression…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen gas in a rat model of branch retinal vein occlusion via decreasing VEGF-α expression

This animal study examined Protective effects of hydrogen gas in a rat model of branch retinal vein occlusion via decreasing VEGF-α expression. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Our findings demonstrate that inhalation of hydrogen gas could alleviate retinal oedema, shorten reopen time and improve retinal function, and the potential mechanism might…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activated retinal microglia cells.

This in vitro or cellular study examined Molecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activated retinal microglia cells. The abstract describes Cell culture / in vitro model. The abstract reports: The results in the present study indicate that miR-9, miR-199 and miR-21 play an important role in the anti-inflammatory regulation of LPS-activated microglia cells…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Comparative Efficiency of Intraperitoneal and Intravitreous Injection of Hydrogen Rich Saline against -Methyl–Nitrosourea Induced Retinal Degeneration: A Topographic Study.

This animal study examined The Comparative Efficiency of Intraperitoneal and Intravitreous Injection of Hydrogen Rich Saline against -Methyl–Nitrosourea Induced Retinal Degeneration: A Topographic Study. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Particularly, the topographic measurements suggested that the IV delivery of HRS could alleviate MNU induced photoreceptor degeneration in the posterior retina. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of Post-Treatment Hydrogen Gas Inhalation on Uveitis Induced by Endotoxin in Rats.

This animal study examined Effects of Post-Treatment Hydrogen Gas Inhalation on Uveitis Induced by Endotoxin in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation and oxyhydrogen. The abstract reports: RESULTS No statistically significant differences existed in the graded score of uveitis and the b-wave peak time in the Dark-adapted 3.0 ERG among the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effect of saturated hydrogen saline against blue light-induced retinal damage in rats.

This animal study examined Protective effect of saturated hydrogen saline against blue light-induced retinal damage in rats. The abstract describes Rat model; sample size 30; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 6 hours. The abstract reports: Saturated hydrogen saline could protect the retina from light-induced damage by attenuating oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.

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Therapeutic effect of molecular hydrogen in corneal UVB-induced oxidative stress and corneal photodamage.

This animal study examined Therapeutic effect of molecular hydrogen in corneal UVB-induced oxidative stress and corneal photodamage. The abstract describes Rabbit model. The abstract reports: We previously found that UVB irradiation of the cornea caused the imbalance between the antioxidant and prooxidant enzymes in the corneal epithelium, followed by…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline promotes survival of retinal ganglion cells in a rat model of optic nerve crush.

This animal study examined Hydrogen-rich saline promotes survival of retinal ganglion cells in a rat model of optic nerve crush. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 14 days. The abstract reports: These results demonstrated that H₂ protects RGCs and helps preserve the visual function after ONC and had a neuroprotective effect in a rat model…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline ameliorates the retina against light-induced damage in rats.

This animal study examined Hydrogen-rich saline ameliorates the retina against light-induced damage in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results showed that the electroretinogram b-wave amplitudes and the mean ONL thicknesses of rats were significantly greater in the HRS prevention (P . This is an automated editorial draft based on the abstract and requires source review before publication.

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