Hydrogen protects mice from radiation induced thymic lymphoma in BALB/c mice.

This animal study examined Hydrogen protects mice from radiation induced thymic lymphoma in BALB/c mice. The abstract describes Mouse model. The abstract reports: Here in this study, we found that H(2) protects mice from radiation induced thymic lymphoma in BALB/c mice. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice.

This uncontrolled human study examined Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Hydrogen has potential for improving the quality of life of patients during chemotherapy by efficiently mitigating the side effects of cisplatin. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-water enhances 5-fluorouracil-induced inhibition of colon cancer.

This animal study examined Hydrogen-water enhances 5-fluorouracil-induced inhibition of colon cancer. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Furthermore, hydrogen water enhanced cell apoptosis in cancer cells, resulting in a marked increase in the expression of p-AMPK, AIF and Caspase 3 in…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hyperbaric hydrogen therapy: a possible treatment for cancer.

This animal study examined Hyperbaric hydrogen therapy: a possible treatment for cancer. The abstract describes Mouse model. The abstract reports: Marked aggression of the tumors was found, leading to the possibility that hyperbaric hydrogen therapy might also prove to be of significance in the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Influence of hydrogen-occluding-silica on migration and apoptosis in human esophageal cells in vitro

This in vitro or cellular study examined Influence of hydrogen-occluding-silica on migration and apoptosis in human esophageal cells in vitro. The abstract describes Epithelial cell model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that KYSE-70 cells and HEEpiCs were generally inhibited by H-silica administration, and there was a significant proliferation-inhibitory effect in an H-silica…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Attenuates Chronic Inflammation and Delays the Onset of Ultraviolet B-Induced Skin Carcinogenesis in Mice.

This animal study examined Molecular Hydrogen Attenuates Chronic Inflammation and Delays the Onset of Ultraviolet B-Induced Skin Carcinogenesis in Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water and hydrogen inhalation. The abstract reports: These findings suggest that continuous H administration attenuates inflammation-associated early UVB carcinogenesis through modulation of the IL-6/STAT3 and ERK/JNK pathways, supporting its use as…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen: an advanced and safest gas option for cancer treatment.

This uncontrolled human study examined Hydrogen: an advanced and safest gas option for cancer treatment. The abstract describes Human participants; hydrogen delivered as hydrogen water and hydrogen inhalation and hydrogen-rich saline. The abstract reports: Currently available cancer treatment options, such as surgery, chemotherapy, radiation, and immunotherapy, are limited, and the results could be unsatisfactory due to systemic toxicity…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Combined treatment with dissolved hydrogen molecule and platinum nanocolloid exerts carcinostatic/carcinocidal effects by increasing hydrogen peroxide generation and cell death in the human gastric cancer cell line NUGC-4

This in vitro or cellular study examined Combined treatment with dissolved hydrogen molecule and platinum nanocolloid exerts carcinostatic/carcinocidal effects by increasing hydrogen peroxide generation and cell death in the human gastric cancer cell line NUGC-4. The abstract describes Fibroblast model. The abstract reports: We have previously demonstrated that combined treatment with dissolved hydrogen molecule (H) and platinum nanocolloid (Pt-nc) has carcinostatic effects and that increased intracellular reactive…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Controlled release of hydrogen by implantation of magnesium induces P53-mediated tumor cells apoptosis.

This animal study examined Controlled release of hydrogen by implantation of magnesium induces P53-mediated tumor cells apoptosis. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation and hydrogen-rich saline. The abstract reports: We find that the localized release of hydrogen increases the expression level of P53 tumor suppressor proteins, as demonstrated by the RNA sequencing and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway

This animal study examined Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: This study extended our original analysis of the ability of hydrogen to stimulate NLRP3 inflammasome/GSDMD activation in pyroptosis and revealed possible mechanism (s) for…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Role of Mast Cells in the Remodeling Effects of Molecular Hydrogen on the Lung Local Tissue Microenvironment under Simulated Pulmonary Hypertension.

This animal study examined The Role of Mast Cells in the Remodeling Effects of Molecular Hydrogen on the Lung Local Tissue Microenvironment under Simulated Pulmonary Hypertension. The abstract describes Rat model. The abstract reports: MPH resulted in a significantly increased number of MCs in both the pneumatic and respiratory parts of the lungs, an increased number of tryptase-positive…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen ameliorates pulmonary hypertension in rats by anti-inflammatory and antioxidant effects.

This animal study examined Hydrogen ameliorates pulmonary hypertension in rats by anti-inflammatory and antioxidant effects. The abstract describes Rat model. The abstract reports: Molecular hydrogen ameliorates MCT-induced PAH in rats by suppressing macrophage accumulation, reducing oxidative stress and modulating the STAT3/NFAT axis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Adjuvant Molecular Hydrogen Therapy in SLE-associated Pulmonary Arterial Hypertension: A Case Report on Immunomodulatory Effects on Regulatory and Effector Lymphocytes

This case report or case series examined Adjuvant Molecular Hydrogen Therapy in SLE-associated Pulmonary Arterial Hypertension: A Case Report on Immunomodulatory Effects on Regulatory and Effector Lymphocytes. The abstract describes Human participants. The abstract reports: This case study suggests that molecular hydrogen therapy may be a promising treatment for patients with SLE-PAH, particularly due to its immunomodulatory effects. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen therapy in musculoskeletal conditions: An evidence-based review and critical analysis.

This narrative review examined Molecular hydrogen therapy in musculoskeletal conditions: An evidence-based review and critical analysis. The abstract describes Published literature review; hydrogen delivered as hydrogen water. The abstract reports: Preclinical models consistently showed reductions in reactive oxygen species, inflammatory cytokines, and improved cell viability. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Prevents Osteoclast Activation in a Glucocorticoid-Induced Osteoporosis Zebrafish Scale Model.

This animal study examined Molecular Hydrogen Prevents Osteoclast Activation in a Glucocorticoid-Induced Osteoporosis Zebrafish Scale Model. The abstract describes Zebrafish model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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