Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats.
This animal study examined Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Attenuated N-methyl-N-Nitrosourea Induced Corneal Endothelial Injury by Upregulating Anti-Apoptotic Pathway.
This in vitro or cellular study examined Molecular Hydrogen Attenuated N-methyl-N-Nitrosourea Induced Corneal Endothelial Injury by Upregulating Anti-Apoptotic Pathway. The abstract describes Endothelial cell model; hydrogen delivered as hydrogen-rich saline; reported duration 14 days. The abstract reports: This study suggests that topical application of H2 could protect CECs against corneal damage factors through anti-apoptotic effect, reduce the incidence and severity of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen protects mice against polymicrobial sepsis by ameliorating endothelial dysfunction via an Nrf2/HO-1 signaling pathway.
This animal study examined Molecular hydrogen protects mice against polymicrobial sepsis by ameliorating endothelial dysfunction via an Nrf2/HO-1 signaling pathway. The abstract describes Mouse model. The abstract reports: We found that molecular hydrogen (H2) exerts an anti-inflammatory effect. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich medium suppresses the generation of reactive oxygen species, elevates the Bcl-2/Bax ratio and inhibits advanced glycation end product-induced apoptosis.
This in vitro or cellular study examined Hydrogen-rich medium suppresses the generation of reactive oxygen species, elevates the Bcl-2/Bax ratio and inhibits advanced glycation end product-induced apoptosis. The abstract describes Endothelial cell model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Alleviates Cellular Senescence in Endothelial Cells.
This in vitro or cellular study examined Molecular Hydrogen Alleviates Cellular Senescence in Endothelial Cells. The abstract describes HUVEC model; hydrogen delivered as hydrogen water. The abstract reports: H2has long-lasting antioxidant and anti-aging effects on vascular endothelial cells through the Nrf2 pathway, even after transient exposure to H2. Hydrogen-rich water may thus…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats.
This animal study examined Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: HRS was demonstrated to attenuate CPB‑induced myocardial injury, suppress AQP‑1 and AQP‑4 expression following CPB treatment and protect myocardial cells via the PI3K/Akt signaling…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen prevents corneal endothelial damage in phacoemulsification cataract surgery : Scientific Reports
This animal study examined Hydrogen prevents corneal endothelial damage in phacoemulsification cataract surgery : Scientific Reports. The abstract describes Rabbit model. The abstract reports: ESR showed a significantly decreased signal magnitude, and fluorescence intensity by oxidized HPF was significantly less in the H2-dissolved solution. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration.
This in vitro or cellular study examined Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: Recent evidence suggests that molecular hydrogen has therapeutic value for disease states that involve inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice.
This animal study examined Molecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConsumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function
This uncontrolled human study examined Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: H2 may protect the vasculature from shear stress-derived detrimental ROS, such as the hydroxyl radical, by maintaining the nitric oxide-mediated vasomotor response. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen alleviates myocardial infarction by impeding apoptosis via ROS-mediated mitochondrial endogenous pathway
This animal study examined Hydrogen alleviates myocardial infarction by impeding apoptosis via ROS-mediated mitochondrial endogenous pathway. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Overall, hydrogen inhalation reduces myocardial infarct size, improves mitochondrial dysfunction, and modulates the levels of apoptosis-related substances. Importantly, Hydrogen reduces acute myocardial infarction damage…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of Molecular Hydrogen in the Pathophysiology and Management of Cardiovascular and Metabolic Diseases.
This narrative review examined Effects of Molecular Hydrogen in the Pathophysiology and Management of Cardiovascular and Metabolic Diseases. The abstract describes Published literature review. The abstract reports: In the last two decades, mounting evidence has demonstrated that both endogenously produced and exogenously administered , whether via inhalation or -rich water (HRW),…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen promotes retinal vascular regeneration and attenuates neovascularization and neuroglial dysfunction in oxygen-induced retinopathy mice.
This animal study examined Molecular hydrogen promotes retinal vascular regeneration and attenuates neovascularization and neuroglial dysfunction in oxygen-induced retinopathy mice. The abstract describes Mouse model; reported duration 5 days. The abstract reports: Collectively, our results indicate that H could be a promising therapeutic agent for POR treatment and that its beneficial effect in human ROP might…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen therapy as a potential therapeutic intervention in heart disease: from the past evidence to future application.
This animal study examined Hydrogen therapy as a potential therapeutic intervention in heart disease: from the past evidence to future application. The abstract describes Animal model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: It has been demonstrated that molecular hydrogen exerts antioxidant, anti-inflammatory, and antiapoptotic effects, leading to cardioprotective benefits. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen: potential in mitigating oxidative-stress-induced radiation injury .
This animal study examined Molecular hydrogen: potential in mitigating oxidative-stress-induced radiation injury. The abstract describes Rat model. The abstract reports: Uncontrolled production of oxygen and nitrogen radicals results in oxidative and nitrosative stresses that impair cellular functions and have been regarded as causative common…. This is an automated editorial draft based on the abstract and requires source review before publication.
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