Role of Molecular Hydrogen in Skin Diseases and its Impact in Beauty.

This uncontrolled human study examined Role of Molecular Hydrogen in Skin Diseases and its Impact in Beauty. The abstract describes Human participants. The abstract reports: In today's society, healthy skin and a beautiful appearance are considered the foundation of general well-being. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas production is associated with reduced interleukin-1β mRNA in peripheral blood after a single dose of acarbose in Japanese type 2 diabetic patients.

This uncontrolled human study examined Hydrogen gas production is associated with reduced interleukin-1β mRNA in peripheral blood after a single dose of acarbose in Japanese type 2 diabetic patients. The abstract describes Human participants; reported duration 2 days. The abstract reports: Our results suggest that an increase in hydrogen gas production is inversely associated with a reduction of the peripheral blood IL-1β mRNA level after…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Different types of molecular hydrogen donors and their pharmacokinetics in vivo].

This animal study examined [Different types of molecular hydrogen donors and their pharmacokinetics in vivo]. The abstract describes Animal model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich PBS protects cultured human cells from ionizing radiation-induced cellular damage

This in vitro or cellular study examined Hydrogen-rich PBS protects cultured human cells from ionizing radiation-induced cellular damage. The abstract describes Lymphocyte cell model. The abstract reports: Compared to cells pretreated without hydrogen, we demonstrated that treating cells with hydrogen-rich PBS before irradiation could significantly inhibit IR-induced apoptosis, increase viability of…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hyperbaric Oxygen Combined With Hydrogen-rich Saline Protect Against Acute Lung Injury Induced by Lipopolysaccharide in Rat Model

This animal study examined Hyperbaric Oxygen Combined With Hydrogen-rich Saline Protect Against Acute Lung Injury Induced by Lipopolysaccharide in Rat Model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Results: In the groups treated with HRS and HBO, pulmonary pathological data, wet-dry weight ratio and immflammatory factors in the pulmonary tissues and avelar…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen: current knowledge on mechanism in alleviating free radical damage and diseases

This narrative review examined Molecular hydrogen: current knowledge on mechanism in alleviating free radical damage and diseases. The abstract describes Published literature review. The abstract reports: All these pathological damages are concomitant with overproduction of reactive oxygen species (ROS) where molecular hydrogen has been widely demonstrated as a selective antioxidant. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of hydrogen-rich saline on rats with acute carbon monoxide poisoning.

This animal study examined Effects of hydrogen-rich saline on rats with acute carbon monoxide poisoning. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: H(2)-rich saline may effectively protect the brain from injury after acute CO poisoning. The mechanism of this protection may be related to lessening oxidative…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Protective effect of hydrogen-rich water on oxidative stress cell model and the impact of the phosphatidylinositol 3 kinase/protein kinase B pathway].

This animal study examined [Protective effect of hydrogen-rich water on oxidative stress cell model and the impact of the phosphatidylinositol 3 kinase/protein kinase B pathway]. The abstract describes Mouse model; hydrogen delivered as hydrogen water; reported duration 20 minutes. The abstract reports: Hydrogen-rich water activates the PI3K/Akt pathway, thereby mediates mice astrocytes to exert the biological function of antioxidant. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages.

This animal study examined Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation; reported duration 42 days. The abstract reports: Hydrogen inhalation (75%) ameliorated SCI in vivo and attenuated neuronal mechanical injuries in vitro, and its protective effect on spinal cord neurons was exerted…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β Signaling Pathway in Rats.

This animal study examined Hydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β Signaling Pathway in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The PI3K/Akt/GSK3β signaling pathway plays an important role in the mechanism of CPB-induced brain injury. HRS can reduce CPB-induced brain injury and inhibit CMEC…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline mediates neuroprotection through the regulation of endoplasmic reticulum stress and autophagy under hypoxia-ischemia neonatal brain injury in mice.

This animal study examined Hydrogen-rich saline mediates neuroprotection through the regulation of endoplasmic reticulum stress and autophagy under hypoxia-ischemia neonatal brain injury in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results showed that HS treatment significantly improved brain edema and decreased infarct volume. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis.

This animal study examined Inhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis. The abstract describes Mouse model; reported duration 60 min. The abstract reports: CLP mice showed obvious brain injury characterized by aggravated pathological damage, BBB disruption and brain edema at 24h after CLP operation, which was markedly…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen exerts neuroprotective effects on OGD/R damaged neurons in rat hippocampal by protecting mitochondrial function via regulating mitophagy mediated by PINK1/Parkin signaling pathway.

This uncontrolled human study examined Hydrogen exerts neuroprotective effects on OGD/R damaged neurons in rat hippocampal by protecting mitochondrial function via regulating mitophagy mediated by PINK1/Parkin signaling pathway. The abstract describes Human participants. The abstract reports: The results of MTT indicated that H2 and RAP could increase cell viability after OGD/R treatment, while 3-MA further aggravated injury and inhibited the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of molecular hydrogen on hepatotoxicity induced by sub-chronic exposure to chlorpyrifos in rats.

This animal study examined Protective effects of molecular hydrogen on hepatotoxicity induced by sub-chronic exposure to chlorpyrifos in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 8 weeks. The abstract reports: The results obtained suggest that HRW intake can protect rats from CPF induced hepatotoxicity, and the oxidative stress signaling and the mitochondrial pathway may…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Coadministration of hydrogen gas as part of the carrier gas mixture suppresses neuronal apoptosis and subsequent behavioral deficits caused by neonatal exposure to sevoflurane in mice.

This animal study examined Coadministration of hydrogen gas as part of the carrier gas mixture suppresses neuronal apoptosis and subsequent behavioral deficits caused by neonatal exposure to sevoflurane in mice. The abstract describes Mouse model; sample size 8. The abstract reports: Western blot analysis showed that coadministration of 1.3% hydrogen gas significantly (P < 0.001) reduced the level of neuronal apoptosis to approximately 40% compared…. This is an automated editorial draft based on the abstract and requires source review before publication.

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