Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
Ischemia-reperfusion (IR) injury is a kind of injury resulting from the restoration of the blood supply after blood vessel closure during liver transplantation and is the main cause of graft failure. The pathophysiological mechanisms of hepatic IR include a variety of oxidative…
Read ArticleTwo groups of mice received alkaline water for three years—one produced by a water ionizer and one prepared from a concentrated alkaline solution—while controls received tap water. Survival…
Read ArticleElectrolyzed-reduced water altered growth and telomere-related measurements in cultured A549 and HeLa cancer cells, while the reported telomerase activity did not materially change. This is a cell-culture observation…
Read ArticleHydrogen-rich saline reduced decompression-sickness incidence and associated lung and spinal-cord injury markers in rats. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied.…
Read ArticleThe study evaluated 30 women with high sebum and acne and a healthy comparison group of 30 women with low sebum. After four weekly treatments using alkaline water…
Read ArticleBACKGROUND: Chemotherapy is a first-line treatment for advanced and metastatic bladder cancer, but the unsatisfactory objective response rate to this treatment yields poor 5-year patient survival. Only PD-1/PD-L1-based…
Read ArticleHydrogen-rich PBS protects cultured human cells from ionizing radiation-induced cellular damage Compared to cells pretreated without hydrogen, the researchers demonstrated that treating cells with hydrogen-rich PBS before irradiation…
Read ArticleNHE water diminished hydroxyl radicals as demonstrated by ESR in a cell-free system. These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research…
Read ArticleThis animal study examined Atomic hydrogen surrounded by water molecules, H(H2O)m, modulates basal and UV-induced gene expressions in human skin in vivo. The abstract describes Animal model. The…
Read ArticleIn this case report, adjunctive hydrogen inhalation was followed by temporary clinical stabilization and longitudinal immune changes in a 49-year-old man with refractory septic shock. The report described…
Read ArticleHydrogen inhalation was associated with greater reductions in systolic and diastolic blood pressure than control treatment through 24 weeks.
Read Article1 Although the medical efficacy of hydrogen gas remains controversial, several studies have reported the risk of associated explosions. This source-grounded publication contributes evidence relevant to molecular hydrogen…
Read ArticleIt has been suggested that saturated hydrogen saline may downregulate expression of nuclear factor (NF)-κB, leading to a decrease in Beclin-1 transcription and inhibition of autophagy. This source-grounded…
Read ArticleThe researchers found that H₂-rich medium pretreatment reduced •OH level in AHH-1 cells. These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research…
Read ArticleIn 8 patients, however, the mean proportion of reversibly oxidized albumin in outlet serum was significantly lower than that in inlet serum following the H₂-HD session, whereas no…
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