Protective effect of hydrogen-rich water on spermatogenesis in high-fat diet obese rats.
This animal study examined Protective effect of hydrogen-rich water on spermatogenesis in high-fat diet obese rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that the HFD significantly increased food intake, body weight, and lee index, all of which were reduced in the HRW-treated obese…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe effect of hydrogen gas on the oxidative stress response in adipose tissue.
This uncontrolled human study examined The effect of hydrogen gas on the oxidative stress response in adipose tissue. The abstract describes Human participants. The abstract reports: The immunostaining results showed that HO-1 and Nrf2 expression levels were significantly decreased in the hydrogenated group, whereas SOD expression levels increased, but did…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe Effects of 8-Week Hydrogen-Rich Water Consumption on Appetite, Body Composition, Sleep Quality, and Circulating Glucagon-like Peptide-1 in Obese Men and Women (HYDRAPPET): A Randomized Controlled Trial.
This randomized controlled trial examined The Effects of 8-Week Hydrogen-Rich Water Consumption on Appetite, Body Composition, Sleep Quality, and Circulating Glucagon-like Peptide-1 in Obese Men and Women (HYDRAPPET): A Randomized Controlled Trial. The abstract describes Human participants; sample size 36; hydrogen delivered as hydrogen water. The abstract reports: The results demonstrated that hydrogen-rich water significantly mitigated cravings ( = 0.05), improved subjective sleep quality ( = 0.05), reduced total cholesterol ( =…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen affects body composition, metabolic profiles, and mitochondrial function in middle-aged overweight women.
Molecular hydrogen (H) effectively treats obesity-related disorders in animal models, yet no studies have investigated the effectiveness and safety of H for improving biomarkers of obesity in humans. In this double blind, placebo-controlled, crossover pilot trial, we evaluated the effects of H intervention on body composition, hormonal status, and mitochondrial function in ten (n = 10) middle-aged overweight women. Volunteers received either hydrogen-generating minerals (supplying ~6 ppm of H per day) or placebo by oral administration of caplets for 4 weeks.
Read MoreTreatment with hydrogen-rich water protects against thioacetamide-induced hepatic encephalopathy in rats through stabilizing liver-brain disturbance.
This animal study examined Treatment with hydrogen-rich water protects against thioacetamide-induced hepatic encephalopathy in rats through stabilizing liver-brain disturbance. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: The results showed that hydrogen-rich water can improve the behavioral changes of the HE rats, reduce blood ammonia, reduce liver function damage, alleviate the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRole of molecular hydrogen in obesity treatment: modulation of GLP-1, irisin, and PGC-1α for improved metabolism.
The increasing prevalence of obesity and non-communicable diseases has become a major global health concern, contributing to significant morbidity and mortality rates. These conditions not only burden healthcare systems but also affect the individual’s quality of life worldwide. As these challenges continue to grow, there is a pressing need to explore treatment options that are effective, affordable, and widely accessible.
Read MoreiTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice.
This uncontrolled human study examined iTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: The results of the H&E, and Nissl staining indicated that the CLP mice had a significant brain injury, which was characterized by aggravated pathological…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteins.
This animal study examined Hydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteins. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Based on our results, HRW treatment was able to reduce brain infarct volume and improve neurological function following ischemic brain injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen rich saline reduces immune-mediated brain injury in rats with acute carbon monoxide poisoning.
This animal study examined Hydrogen rich saline reduces immune-mediated brain injury in rats with acute carbon monoxide poisoning. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: CO-exposed rats showed the increase in neuron loss and the decrease in antioxidant capacities. And H(2) rich saline given after CO poisoning can prevent…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates spinal cord hemisection-induced testicular injury in rats.
This animal study examined Hydrogen-rich saline attenuates spinal cord hemisection-induced testicular injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results indicated that hSCI significantly decreased the hind limb neurological function, testis index, MSTD, and MSET, and induced severe testicular morphological injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen is neuroprotective against surgically induced brain injury.
This controlled preclinical study evaluated whether inhaled molecular hydrogen reduced brain injury caused by a surgical procedure in adult male Sprague-Dawley rats. Animals underwent sham surgery, surgically induced brain injury without treatment, or surgically induced brain injury with 2.9% hydrogen inhaled concurrently during the 60-minute surgical procedure.
Read MoreHydrogen exerts neuroprotective effects by inhibiting oxidative stress in experimental diabetic peripheral neuropathy rats.
This animal study examined Hydrogen exerts neuroprotective effects by inhibiting oxidative stress in experimental diabetic peripheral neuropathy rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation and hydrogen-rich saline. The abstract reports: Further studies showed that hydrogen significantly upregulated the expression of nuclear factor erythroid-2-related factor 2 and downstream proteins such as catalase and hemeoxygenase-1 in…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA randomized controlled double-blind study on the brain protection of infantile patients with epileptic spasm syndrome through atomized inhalation of hydrogen-oxygen gas.
Hydrogen-oxygen nebulization inhalation has a brain-protective effect. This study aims to evaluate its short-term efficacy and safety as an adjuvant treatment for infantile epileptic spasms syndrome (IESS). A prospective randomized double-blind controlled trial enrolled 53 IESS children (Nov 2021-Nov 2023), randomized via a random number table into a hydrogen-oxygen inhalation group (27 cases, 66.6% H₂/33.3% O₂ nebulization) and an air inhalation group (26 cases, medical air nebulization).
Read MoreHydrogen alleviates hypoxic-ischaemic brain damage in neonatal rats by inhibiting injury of brain pericytes.
This animal study examined Hydrogen alleviates hypoxic-ischaemic brain damage in neonatal rats by inhibiting injury of brain pericytes. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that HRW significantly attenuated HI-induced oxidative stress in the brain pericytes of neonatal rats, partly through the Nrf2-HO-1 pathway, further improving…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreDGKζ in Glycerophospholipid Metabolism Regulates the DAG and PA Balance and Interacts With PTEN to Alleviate Brain Damage in Septic Mice With Hydrogen Inhalation: A Comparative Metabolomic and Phosphoproteomic Analysis.
This narrative review examined DGKζ in Glycerophospholipid Metabolism Regulates the DAG and PA Balance and Interacts With PTEN to Alleviate Brain Damage in Septic Mice With Hydrogen Inhalation: A Comparative Metabolomic and Phosphoproteomic Analysis. The abstract describes Published literature review; hydrogen delivered as hydrogen inhalation. The abstract reports: The correlated differential phosphoproteins found in the combined metabolomic and phosphoproteomic analyses participated in 131 pathways, and the differentially abundant metabolites were involved in…. This is an automated editorial draft based on the abstract and requires source review before publication.
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