Molecular Hydrogen Alleviates Cellular Senescence in Endothelial Cells.
This in vitro or cellular study examined Molecular Hydrogen Alleviates Cellular Senescence in Endothelial Cells. The abstract describes HUVEC model; hydrogen delivered as hydrogen water. The abstract reports: H2has long-lasting antioxidant and anti-aging effects on vascular endothelial cells through the Nrf2 pathway, even after transient exposure to H2. Hydrogen-rich water may thus…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe effects of hydrogen gas inhalation during ex vivo lung perfusion on donor lungs obtained after cardiac death.
This animal study examined The effects of hydrogen gas inhalation during ex vivo lung perfusion on donor lungs obtained after cardiac death. The abstract describes Animal model; sample size 5; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen gas inhalation during EVLP improved the function of DCD lungs, which may increase the utilization of DCD lungs. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats.
This animal study examined Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: HRS was demonstrated to attenuate CPB‑induced myocardial injury, suppress AQP‑1 and AQP‑4 expression following CPB treatment and protect myocardial cells via the PI3K/Akt signaling…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen prevents corneal endothelial damage in phacoemulsification cataract surgery : Scientific Reports
This animal study examined Hydrogen prevents corneal endothelial damage in phacoemulsification cataract surgery : Scientific Reports. The abstract describes Rabbit model. The abstract reports: ESR showed a significantly decreased signal magnitude, and fluorescence intensity by oxidized HPF was significantly less in the H2-dissolved solution. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats.
This animal study examined Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Protective effect of hydrogen (H(2)) gas on cardiac ischemia-reperfusion (I/R) injury has been demonstrated previously. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration.
This in vitro or cellular study examined Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: Recent evidence suggests that molecular hydrogen has therapeutic value for disease states that involve inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling.
This animal study examined Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Our results showed a protective effect of HRS on pressure overload-induced cardiac hypertrophy in rats, which may be associated to a decreasing in JAK-STAT…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice.
This animal study examined Molecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConsumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice.
This in vitro or cellular study examined Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: We have found that hydrogen (dihydrogen; H(2)) acts as an effective antioxidant to reduce oxidative stress [I. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConsumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function
This uncontrolled human study examined Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: H2 may protect the vasculature from shear stress-derived detrimental ROS, such as the hydroxyl radical, by maintaining the nitric oxide-mediated vasomotor response. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAdministration of hydrogen-rich water prevents vascular aging of the aorta in LDL receptor-deficient mice.
This in vitro or cellular study examined Administration of hydrogen-rich water prevents vascular aging of the aorta in LDL receptor-deficient mice. The abstract describes Endothelial cell model; hydrogen delivered as hydrogen water; reported duration 13 weeks. The abstract reports: Recent studies showed that senescent cells are involved in the development and progression of atherosclerosis, and eliminating senescent cells suppresses the senescence-associated secretory phenotype. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen alleviates myocardial infarction by impeding apoptosis via ROS-mediated mitochondrial endogenous pathway
This animal study examined Hydrogen alleviates myocardial infarction by impeding apoptosis via ROS-mediated mitochondrial endogenous pathway. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Overall, hydrogen inhalation reduces myocardial infarct size, improves mitochondrial dysfunction, and modulates the levels of apoptosis-related substances. Importantly, Hydrogen reduces acute myocardial infarction damage…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of Molecular Hydrogen in the Pathophysiology and Management of Cardiovascular and Metabolic Diseases.
This narrative review examined Effects of Molecular Hydrogen in the Pathophysiology and Management of Cardiovascular and Metabolic Diseases. The abstract describes Published literature review. The abstract reports: In the last two decades, mounting evidence has demonstrated that both endogenously produced and exogenously administered , whether via inhalation or -rich water (HRW),…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen promotes retinal vascular regeneration and attenuates neovascularization and neuroglial dysfunction in oxygen-induced retinopathy mice.
This animal study examined Molecular hydrogen promotes retinal vascular regeneration and attenuates neovascularization and neuroglial dysfunction in oxygen-induced retinopathy mice. The abstract describes Mouse model; reported duration 5 days. The abstract reports: Collectively, our results indicate that H could be a promising therapeutic agent for POR treatment and that its beneficial effect in human ROP might…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen therapy as a potential therapeutic intervention in heart disease: from the past evidence to future application.
Cardiovascular disease is the leading cause of mortality worldwide. Excessive oxidative stress and inflammation play an important role in the development and progression of cardiovascular disease. Molecular hydrogen, a small colorless and odorless molecule, is considered harmless in daily life when its concentration is below 4% at room temperature.
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