Therapeutic Effects of Hydrogen in Animal Models of Parkinson’s Disease

This in vitro or cellular study examined Therapeutic Effects of Hydrogen in Animal Models of Parkinson’s Disease. The abstract describes Cell culture / in vitro model. The abstract reports: Thus, it is strongly suggested that hydrogen might provide a great advantage to prevent or minimize the onset and progression of PD. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of hydrogen gas elevates urinary 8-hydroxy-2′-deoxyguanine in Parkinson’s disease.

This randomized controlled trial examined Inhalation of hydrogen gas elevates urinary 8-hydroxy-2′-deoxyguanine in Parkinson’s disease. The abstract describes Human participants; sample size 20; hydrogen delivered as hydrogen water; reported duration 10 minutes. This is an automated editorial draft based on the abstract and requires source review before publication.

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Role and mechanism of molecular hydrogen in the treatment of Parkinson’s diseases.

This narrative review examined Role and mechanism of molecular hydrogen in the treatment of Parkinson’s diseases. The abstract describes Published literature review. The abstract reports: While preclinical studies demonstrate promising results, clinical trials conducted thus far have yielded mixed outcomes, with some trials reporting limited or no therapeutic benefit. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of hydrogen gas inhalation on L-DOPA-induced dyskinesia.

This uncontrolled human study examined Effects of hydrogen gas inhalation on L-DOPA-induced dyskinesia. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of concomitant use of hydrogen water and photobiomodulation on Parkinson disease: A pilot study.

This uncontrolled human study examined Effects of concomitant use of hydrogen water and photobiomodulation on Parkinson disease: A pilot study. The abstract describes Human participants; sample size 18; hydrogen delivered as hydrogen water. The abstract reports: This novel, proof-of-concept study demonstrated that PBM+H2 therapy is safe and reduces disease severity. A larger-scaled clinical trial is warranted to completely investigate the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Water Ameliorates Murine Chronic Graft-versus-Host Disease through Antioxidation.

This animal study examined Hydrogen-Rich Water Ameliorates Murine Chronic Graft-versus-Host Disease through Antioxidation. The abstract describes Mouse model; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: Hydrogen gas (H) has been demonstrated that has antioxidative, anti-inflammatory, and antifibrosis effects. This is an automated editorial draft based on the abstract and requires source review before publication.

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Emerging mechanisms and novel applications of hydrogen gas therapy.

This narrative review examined Emerging mechanisms and novel applications of hydrogen gas therapy. The abstract describes Published literature review; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen suppresses oxidative stress by inhibiting the p38 MAPK signaling pathway in preeclampsia.

This animal study examined Hydrogen suppresses oxidative stress by inhibiting the p38 MAPK signaling pathway in preeclampsia. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: It was found that hydrogen-rich saline (LH group) decreased placental MDA, proteinuria, TNF-α, and IL-1β levels in the placental tissues compared with the L…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Electrochemically reduced water exerts superior reactive oxygen species scavenging activity in HT1080 cells than the equivalent level of hydrogen-dissolved water

This in vitro or cellular study examined Electrochemically reduced water exerts superior reactive oxygen species scavenging activity in HT1080 cells than the equivalent level of hydrogen-dissolved water. The abstract describes HT1080 cell model. The abstract reports: ERW has reactive oxygen species (ROS)-scavenging activity and recent studies demonstrated that hydrogen-dissolved water exhibits ROS-scavenging activity. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Water and Lactulose Protect Against Growth Suppression and Oxidative Stress in Female Piglets Fed Toxins Contaminated Diets.

This animal study examined Hydrogen-Rich Water and Lactulose Protect Against Growth Suppression and Oxidative Stress in Female Piglets Fed Toxins Contaminated Diets. The abstract describes Porcine model; hydrogen delivered as hydrogen water; reported duration 25 days. The abstract reports: Results showed that both HRW and LAC treatments significantly attenuated the reduction of average daily gain (ADG) and average daily feed intake (ADFI) caused…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline attenuated neuropathic pain by reducing oxidative stress.

This animal study examined Hydrogen-rich saline attenuated neuropathic pain by reducing oxidative stress. The abstract describes Rat model; sample size 10; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Intrathecal injection of hydrogen-rich saline can decrease oxidative stress and the expression of p38MAPK and BDNF that may contribute to the elevated threshold of…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesis.

This in vitro or cellular study examined Molecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesis. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen suppresses free-radical-induced cell death by mitigating fatty acid peroxidation and mitochondrial dysfunction.

This in vitro or cellular study examined Molecular hydrogen suppresses free-radical-induced cell death by mitigating fatty acid peroxidation and mitochondrial dysfunction. The abstract describes Cell culture / in vitro model. The abstract reports: As a result, H protected the cultured cells against the cytotoxic effects induced by -butyl hydroperoxide; H suppressed cellular fatty acid peroxidation and cell…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases.

This narrative review examined Molecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases. The abstract describes Published literature review; hydrogen delivered as hydrogen water and hydrogen bath. The abstract reports: Hydrogen has biological benefits toward preventive and therapeutic applications; however, the molecular mechanisms underlying the marked effects of small amounts of hydrogen remain elusive. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas inhalation therapy may not work sufficiently to mitigate oxidative stress induced with REBOA

This animal study examined Hydrogen gas inhalation therapy may not work sufficiently to mitigate oxidative stress induced with REBOA. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation; reported duration 180 minutes. The abstract reports: Survival analysis showed no significant differences between the two groups (control vs. hydrogen, 4/5 vs. This is an automated editorial draft based on the abstract and requires source review before publication.

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