Hydrogen-rich water and caffeine for alertness and brain metabolism in sleep-deprived habitual coffee drinkers.

This randomized controlled trial examined Hydrogen-rich water and caffeine for alertness and brain metabolism in sleep-deprived habitual coffee drinkers. The abstract describes Human participants; hydrogen delivered as hydrogen water; reported duration 15 min. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen: an Emerging Therapeutic Medical Gas for Brain Disorders

This narrative review examined Molecular Hydrogen: an Emerging Therapeutic Medical Gas for Brain Disorders. The abstract describes Published literature review. The abstract reports: Since the landmark finding reported in 2007 found that hydrogen reduced the levels of peroxynitrite anions and hydroxyl free radicals in ischemic stroke, molecular…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Neuroprotective potential of molecular hydrogen against perinatal brain injury via suppression of activated microglia.

This animal study examined Neuroprotective potential of molecular hydrogen against perinatal brain injury via suppression of activated microglia. The abstract describes Mouse model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: These results suggested that H2 holds promise for the prevention of inflammation related to perinatal brain injury. This is an automated editorial draft based on the abstract and requires source review before publication.

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PPARα contributes to the therapeutic effect of hydrogen gas against sepsis-associated encephalopathy with the regulation to the CREB-BDNF signaling pathway and hippocampal neuron plasticity-related gene expression.

This animal study examined PPARα contributes to the therapeutic effect of hydrogen gas against sepsis-associated encephalopathy with the regulation to the CREB-BDNF signaling pathway and hippocampal neuron plasticity-related gene expression. The abstract describes Mouse model. The abstract reports: The results showed the expression of PPARα was decreased in SAE mice and that activation of PPARα in septic mice improved the survival rate…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Impact of hydrogen gas inhalation during therapeutic hypothermia on cerebral hemodynamics and oxygenation in the asphyxiated piglet.

This animal study examined Impact of hydrogen gas inhalation during therapeutic hypothermia on cerebral hemodynamics and oxygenation in the asphyxiated piglet. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline reduces delayed neurologic sequelae in experimental carbon monoxide toxicity.

This uncontrolled human study examined Hydrogen-rich saline reduces delayed neurologic sequelae in experimental carbon monoxide toxicity. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 40 min. The abstract reports: This observation demonstrated that hydrogen-rich saline peritoneal injection improves histologic and functional assessment in a rat model of CO encephalopathy. Hydrogen saline has potentials…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of hydrogen gas mitigates sevoflurane‐induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation

This animal study examined Inhalation of hydrogen gas mitigates sevoflurane‐induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.

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Transcriptomic and metabolomic studies on the protective effect of molecular hydrogen against nuclear electromagnetic pulse-induced brain damage.

This animal study examined Transcriptomic and metabolomic studies on the protective effect of molecular hydrogen against nuclear electromagnetic pulse-induced brain damage. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: H is identified as a potent agent against NEMP exposure-induced brain damage and has the potential to be a promising electromagnetic radiation protectant. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hyperbaric hydrogen therapy improves secondary brain injury after head trauma.

This animal study examined Hyperbaric hydrogen therapy improves secondary brain injury after head trauma. The abstract describes Mouse model; sample size 40; reported duration 90 minutes. The abstract reports: Hyperbaric hydrogen therapy may be effective for posttraumatic secondary brain injury. This is an automated editorial draft based on the abstract and requires source review before publication.

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Use of molecular hydrogen as an energy substrate by human pathogenic bacteria.

This animal study examined Use of molecular hydrogen as an energy substrate by human pathogenic bacteria. The abstract describes Mouse model. The abstract reports: Pathogenic Helicobacter species (Helicobacter pylori and H. hepaticus) have the ability to use H(2) through a respiratory hydrogenase, and it was demonstrated that the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Therapeutic effects of hydrogen-rich solution on aplastic anemia in vivo.

This animal study examined Therapeutic effects of hydrogen-rich solution on aplastic anemia in vivo. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. The abstract reports: Our study firstly showed that hydrogen-rich solution accelerated the recovery of either hematological or immunological recovery on aplastic anemia mice. This finding suggests hydrogen-rich…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Neuroprotective and Preventative Effects of Molecular Hydrogen.

This animal study examined Neuroprotective and Preventative Effects of Molecular Hydrogen. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Reverses Nociplastic Pain and Depressive-like Behaviors via Region- and Sex-Dependent Central Mechanisms.

This animal study examined Molecular Hydrogen Reverses Nociplastic Pain and Depressive-like Behaviors via Region- and Sex-Dependent Central Mechanisms. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen water and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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Direct Targets and Subsequent Pathways for Molecular Hydrogen to Exert Multiple Functions: Focusing on Interventions in Radical Reactions

This narrative review examined Direct Targets and Subsequent Pathways for Molecular Hydrogen to Exert Multiple Functions: Focusing on Interventions in Radical Reactions | Bentham Science. The abstract describes Published literature review. The abstract reports: The resulting suppression of Ca2+-signaling inactivates multiple functional NFAT and CREB transcription factors, which may explain H multi-functionality. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen and therapeutic gases for neonatal hypoxic-ischemic encephalopathy: potential neuroprotective adjuncts in translational research.

This in vitro or cellular study examined Hydrogen and therapeutic gases for neonatal hypoxic-ischemic encephalopathy: potential neuroprotective adjuncts in translational research. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.

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