Molecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism.
This animal study examined Molecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism. The abstract describes Mouse model. The abstract reports: The expression of might be regulated indirectly through sequential regulation by H, 4-hydroxy-2-nonenal, and Akt/FoxO1 signaling, as suggested in cultured cell experiments. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMitochondria: one of the vital hubs for molecular hydrogen’s biological functions.
This narrative review examined Mitochondria: one of the vital hubs for molecular hydrogen’s biological functions. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen suppresses superoxide generation in the mitochondrial complex I and reduced mitochondrial membrane potential.
This in vitro or cellular study examined Molecular hydrogen suppresses superoxide generation in the mitochondrial complex I and reduced mitochondrial membrane potential. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein response.
This animal study examined Molecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein response. The abstract describes Mouse model. The abstract reports: We found that H activated the expression of sets of genes regulated by histone H3K27 methylation status. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water affected blood alkalinity in physically active men.
This randomized controlled trial examined Hydrogen-rich water affected blood alkalinity in physically active men. The abstract describes Human participants; hydrogen delivered as hydrogen water; reported duration 14 days. The abstract reports: These results support the hypothesis that HRW administration is safe and may have an alkalizing effect in young physically active men. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water supplementation improves metabolic profile during peripartum period in Gurcu goats and enhances the health and survival of kids.
This animal study examined Hydrogen-rich water supplementation improves metabolic profile during peripartum period in Gurcu goats and enhances the health and survival of kids. The abstract describes hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTherapeutic Potential of Molecular Hydrogen in Metabolic Diseases from Bench to Bedside.
This narrative review examined Therapeutic Potential of Molecular Hydrogen in Metabolic Diseases from Bench to Bedside. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline promotes microglia M2 polarization and complement-mediated synapse loss to restore behavioral deficits following hypoxia-ischemic in neonatal mice via AMPK activation.
This animal study examined Hydrogen-rich saline promotes microglia M2 polarization and complement-mediated synapse loss to restore behavioral deficits following hypoxia-ischemic in neonatal mice via AMPK activation. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: These results demonstrate that HS restored behavioral deficits after HI in neonatal mice. These beneficial effects, in part, involve promoting microglia M2 polarization and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water for improvements of mood, anxiety, and autonomic nerve function in daily life.
This randomized controlled trial examined Hydrogen-rich water for improvements of mood, anxiety, and autonomic nerve function in daily life. The abstract describes Human participants; hydrogen delivered as hydrogen water; reported duration 4 weeks. The abstract reports: In healthy individuals, aging, job stress, and cognitive load over several hours also induce increases in oxidative stress, suggesting that preventing the accumulation of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAdministration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model
This animal study examined Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model. The abstract describes Mouse model. The abstract reports: We have previously demonstrated in the MIA mouse model that maternal administration of H attenuates oxidative damage and neuroinflammation, including induced pro-inflammatory cytokines and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of molecular hydrogen intervention on the gut microbiome in methamphetamine abusers with mental disorder.
This animal study examined Effects of molecular hydrogen intervention on the gut microbiome in methamphetamine abusers with mental disorder. The abstract describes Animal model. The abstract reports: Our results showed that increased SDS and SAS indices and decreased alpha diversity indicated more serious mental disorders and lower bacterial diversity in METH…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePreadministration of Hydrogen-Rich Water Protects Against Lipopolysaccharide-Induced Sepsis and Attenuates Liver Injury.
This animal study examined Preadministration of Hydrogen-Rich Water Protects Against Lipopolysaccharide-Induced Sepsis and Attenuates Liver Injury. The abstract describes Mouse model; hydrogen delivered as hydrogen water; reported duration 3 days. The abstract reports: These results indicate the therapeutic potential of HW in preventing acute injury of the liver with attenuation of an increase in oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Attenuates Acute Kidney Injury After Liver Transplantation via Activating p53-Mediated Autophagy.
This animal study examined Hydrogen-Rich Saline Attenuates Acute Kidney Injury After Liver Transplantation via Activating p53-Mediated Autophagy. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS is able to protect against AKI after liver transplantation partly by reducing apoptosis, which is possibly involved in the modulation of p53-mediated autophagy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreDelivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications
This narrative review examined Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates acute alcohol-induced liver injury by inhibiting JNK activation.
This animal study examined Hydrogen gas alleviates acute alcohol-induced liver injury by inhibiting JNK activation. The abstract describes Mouse model; reported duration 4 days. The abstract reports: Therefore, the results of the present study demonstrated that treatment with exogenous H by intraperitoneal injection may alleviate acute alcohol-induced liver injury by inhibiting…. This is an automated editorial draft based on the abstract and requires source review before publication.
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