Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In aged C57BL/6J mice, the Si-based agent mitigated oxidative stress, suppressed motor performance and body weight decline, and reduced early mortality associated with age-related deterioration. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured…
Read ArticleH2HUBB PLAIN-LANGUAGE TAKEAWAY The study adds to the molecular-hydrogen evidence base, but the available record does not support a firm conclusion about therapeutic benefit. Molecular hydrogen aging and…
Read ArticleIn Ultraviolet-A (UVA) irradiation induces harmful effects on skin cells and accelerates skin aging through oxidative stress, uVA irradiation greatly decreased the cell viability to 30.3% of that…
Read ArticleIn mice, show that H₂ alleviates the progression of aging/injury-superposed senescence, facilitates the recruitment of endogenous cells and the preservation of their regeneration capability, thereby creating a pro-regenerative…
Read ArticleIn 8 healthy participants (4 women), compared to the placebo group, HRW supplementation was associated with increased creatine levels in the right parietal white matter (from 6.0 ±…
Read ArticleIn Adipose-derived mesenchymal stem cells (ADSCs) are promising candidates for regenerative therapies, but their clinical application is limited by cellular aging, these results suggest that hydrogen can regulate…
Read ArticleIn diabetic murine models, this approach accelerated wound closure, enhanced neovascularization, and reduced inflammatory infiltration. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes…
Read ArticleThis systematic review examined dietary supplements might have reciprocal and multilevel interactions with mitochondria network; however, no systematic review assessed the role of different nutraceuticals in mitochondria modification…
Read ArticleIn mice, these findings suggest that molecular hydrogen treatment may regulate neuroinflammation induced by activated microglia and improve depressive-like behavior and short-term cognitive impairment in SAMP8 mice. These…
Read ArticleThe results demonstrated that H₂ alleviated CIH-induced vascular endothelial aging by improving the pathological injury of the aorta, alleviating vasodilation dysfunction, decreasing the expression of oxidative stress and…
Read ArticleIn While disease-modifying antirheumatic drugs (DMARDs) are standard therapy, intolerance to agents like methotrexate (MTX) in elderly or comorbid patients limits options, this case highlights the potential immunomodulatory…
Read ArticleIn rats, instead, HRW specifically attenuated the local senescent microenvironment, with a reduction in both SA-β-gal activity and the expression of p16, p21 within the fracture gap. These…
Read ArticleIn Reactive oxygen species (ROS) play a role in the degeneration of auditory hair cells because of aging, noise trauma, or ototoxic drugs, incubation with a hydrogen-saturated medium…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. It is one and only one "molecular hydrogen" (H₂) that can both penetrate into the mitochondria and scavenge the •OH.…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Hydrogen can also be used for prevention and treatment of various ageing-related diseases, such as neurodegenerative disorders, cardiovascular disease, pulmonary…
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