Transcriptome-Based Evaluation of Hydrogen Gas Effects for Preventing UVA-Induced Photoaging Using an Artificial Skin Model.

This in vitro or cellular study examined Transcriptome-Based Evaluation of Hydrogen Gas Effects for Preventing UVA-Induced Photoaging Using an Artificial Skin Model. The abstract describes Artificial skin model; hydrogen delivered as hydrogen inhalation. The abstract reports: This study demonstrated that photoaging-related transcriptomic changes were detectable in artificial skin under a relatively low UVA dose (7 J/cm/day; total 21 J/cm) with minimal histological…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Intermittent environmental exposure to hydrogen prevents skin photoaging through reduction of oxidative stress.

This animal study examined Intermittent environmental exposure to hydrogen prevents skin photoaging through reduction of oxidative stress. The abstract describes Mouse model. The abstract reports: Our findings support the notion that long-term, intermittent environmental exposure to hydrogen gas in daily life has a beneficial effect on UVA-induced photoaging. Geriatr…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The effect of a low dose hydrogen-oxygen mixture inhalation in midlife/older adults with hypertension: A randomized, placebo-controlled trial.

This randomized controlled trial examined The effect of a low dose hydrogen-oxygen mixture inhalation in midlife/older adults with hypertension: A randomized, placebo-controlled trial. The abstract describes Human participants; sample size 60; hydrogen delivered as oxyhydrogen. The abstract reports: When stratified by age (aged 50-59 years aged 60-70 years), participants in the older H-O group showed a larger reduction in right arm SBP compared with…. This is an automated editorial draft based on the abstract and requires source review before publication.

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A narrative review of hydrogen therapy for COPD: aging-related insights.

This narrative review examined A narrative review of hydrogen therapy for COPD: aging-related insights. The abstract describes Published literature review. The abstract reports: H therapy shows consistent antioxidative, anti-inflammatory, and anti-senescence effects across preclinical and clinical settings, suggesting potential as an adjunctive treatment for COPD in aging…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protection by Inhaled Hydrogen Therapy in a Rat Model of Acute Lung Injury can be Tracked in vivo Using Molecular Imaging

This animal study examined Protection by Inhaled Hydrogen Therapy in a Rat Model of Acute Lung Injury can be Tracked in vivo Using Molecular Imaging. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results suggest the potential utility of these SPECT biomarkers for in vivo assessment of key cellular pathways in the pathogenesis of ALI and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effect of hydrogen-rich water against gentamicin-induced nephrotoxicity in rats using blood oxygenation level-dependent MR imaging.

This animal study examined Protective effect of hydrogen-rich water against gentamicin-induced nephrotoxicity in rats using blood oxygenation level-dependent MR imaging. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 7 days. The abstract reports: Our findings suggested reduced oxygen utility, mainly in the cortex, in gentamicin-induced nephrotoxicity and an ameliorative effect of hydrogen-rich water against GIN. This is an automated editorial draft based on the abstract and requires source review before publication.

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Association Between Hydrogen-Rich Water Consumption and Lower Extremity Function in Older Adults Participating in Community Salons: A Prospective Observational Study

This observational study examined Association Between Hydrogen-Rich Water Consumption and Lower Extremity Function in Older Adults Participating in Community Salons: A Prospective Observational Study. The abstract describes Human participants; sample size 48; hydrogen delivered as hydrogen water. The abstract reports: Results All 48 participants completed follow-up, and no serious adverse events were reported during the study period. This is an automated editorial draft based on the abstract and requires source review before publication.

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A preliminary therapeutic study of the effects of molecular hydrogen on intestinal dysbiosis and small intestinal injury in high-fat diet-loaded senescence-accelerated mice.

This animal study examined A preliminary therapeutic study of the effects of molecular hydrogen on intestinal dysbiosis and small intestinal injury in high-fat diet-loaded senescence-accelerated mice. The abstract describes Mouse model; sample size 10. The abstract reports: Our findings suggest that treatment with molecular hydrogen may affect microbiota profiling and suppress intestinal injury in HFD-loaded SAMP8. This is an automated editorial draft based on the abstract and requires source review before publication.

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Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.

This animal study examined Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence. The abstract describes Mouse model. The abstract reports: Moreover, this result was consistent with the downregulation of expression of the oxidative stress hallmark OGG1. This is an automated editorial draft based on the abstract and requires source review before publication.

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Association of Self-Selected Hydrogen-Rich Water Consumption with 6-Month Changes in Chair-Stand Performance and Gait Speed among Community-Dwelling Older Adults Attending Community Salons.

This observational study examined Association of Self-Selected Hydrogen-Rich Water Consumption with 6-Month Changes in Chair-Stand Performance and Gait Speed among Community-Dwelling Older Adults Attending Community Salons. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Self-selected hydrogen-rich water consumption was associated with better chair-stand performance and gait speed in this pragmatic community setting, but residual confounding remains possible. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of hydrogen-rich water on aging periodontal tissues in rats.

This animal study examined Effects of hydrogen-rich water on aging periodontal tissues in rats. The abstract describes Rat model; sample size 12; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Drinking hydrogen water ameliorated cognitive impairment in senescence-accelerated mice.

This in vitro or cellular study examined Drinking hydrogen water ameliorated cognitive impairment in senescence-accelerated mice. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water; reported duration 30 days. The abstract reports: On the basis of our results, hydrogen water merits further investigation for possible therapeutic/preventative use for age-related cognitive disorders. This is an automated editorial draft based on the abstract and requires source review before publication.

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Redox-Mechanisms of Molecular Hydrogen Promote Healthful Longevity.

This narrative review examined Redox-Mechanisms of Molecular Hydrogen Promote Healthful Longevity. The abstract describes Published literature review. The abstract reports: Excessive levels of both pro- and anti-oxidant species qualify as oxidative stress (OS) and result in damage to molecules and cells. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Alleviates Cellular Senescence in Endothelial Cells.

This in vitro or cellular study examined Molecular Hydrogen Alleviates Cellular Senescence in Endothelial Cells. The abstract describes HUVEC model; hydrogen delivered as hydrogen water. The abstract reports: H2has long-lasting antioxidant and anti-aging effects on vascular endothelial cells through the Nrf2 pathway, even after transient exposure to H2. Hydrogen-rich water may thus…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Administration of hydrogen-rich water prevents vascular aging of the aorta in LDL receptor-deficient mice.

This in vitro or cellular study examined Administration of hydrogen-rich water prevents vascular aging of the aorta in LDL receptor-deficient mice. The abstract describes Endothelial cell model; hydrogen delivered as hydrogen water; reported duration 13 weeks. The abstract reports: Recent studies showed that senescent cells are involved in the development and progression of atherosclerosis, and eliminating senescent cells suppresses the senescence-associated secretory phenotype. This is an automated editorial draft based on the abstract and requires source review before publication.

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