Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This narrative review examined the available molecular-hydrogen literature. Hydrogen (H₂) has been widely used in the chemical industry as a reducing agent. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleIn a complete Freund's Adjuvant-induced RA mouse model, this controlled hydrogen release behavior significantly downregulated pro-inflammatory mediators, protecting chondrocytes from apoptosis and preventing cartilage degradation. These preclinical findings…
Read ArticleIn The researchers found that treatment with H₂ prevented RANKL-induced osteoclast differentiation in RAW264.7 cells and BMMs, treatment with H₂ decreased intracellular reactive oxygen species (ROS) formation, suppressed…
Read ArticleIn 8 participants, however, HW suppressed the reduction in biological antioxidant potential/diacron-reactive oxygen metabolites observed in PW. These findings add human evidence supporting molecular hydrogen's therapeutic potential across…
Read ArticleIn a laboratory model, it is found that the H₂ released from the Mg degradation could scavenge free radicals both in the Fenton Reaction system and bone cancer…
Read ArticleIn rabbits, the eNOS mRNA expression level exhibited no significant difference between the I/R and sham groups after reperfusion but was significantly higher in the IRH group than…
Read ArticleIn mice, this article demonstrated that the administration of hydrogen-rich saline increased the survival rate and clinical score of aGVHD mice. These preclinical findings add evidence supporting molecular…
Read ArticleIn mice, this article demonstrated that administration of hydrogen-rich saline increased survival rate of cGVHD mice. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleIn Following reperfusion, segments of terminal jejunum were rapidly taken and transferred into isolated organ bath and responses to KCl were recorded, hydrogen-rich saline treatment significantly attenuated the…
Read ArticleIn vitro studies also confirmed the anti-proliferative capability of the hydrogen solution and ROS generation in VSMCs induced by PDGF-BB. The authors concluded that hRSS may have a…
Read ArticleIn rats, it was found that systemic HRW treatment slightly suppressed autophagy and then activated the Keap1-Nrf2 signaling pathway by maintaining the Keap1-Nrf2-P62 interaction and improved the osteoporotic…
Read ArticleIn rats, the mRNA and protein expressions of AQP1 in cerebral cortex were significantly decreased after hydrogen-rich water treatment [24-hour AQP1 mRNA (2-△△Ct):5.40±0.21 vs.7.50±0.26, 24-hour AQP1 protein (gray…
Read ArticleIn rats, by scavenging ROS and inflammation via active hydrogen, the oxidative stress is relieved and the levels of inflammation cytokines are reduced by the authors' micromotors, showing…
Read ArticleIn a laboratory model, treatment with hydrogen reduced Ang II- or AAC-induced oxidative stress, which was reflected by diminishing the induction of reactive oxygen species (ROS) in Ang…
Read ArticleIn a laboratory model, an electrochemical H₂ microsensor detected increased levels of H₂ at three anatomical sites with a response time of about 30 s. The authors concluded…
Read Article