Hydrogen-rich water supplementation promotes muscle recovery after two strenuous training sessions performed on the same day in elite fin swimmers: randomized, double-blind, placebo-controlled, crossover trial

This randomized controlled trial examined Hydrogen-rich water supplementation promotes muscle recovery after two strenuous training sessions performed on the same day in elite fin swimmers: randomized, double-blind, placebo-controlled, crossover trial. The abstract describes Human participants; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen improves glycemic control in type1 diabetic animal model by promoting glucose uptake into skeletal muscle.

This animal study examined Hydrogen improves glycemic control in type1 diabetic animal model by promoting glucose uptake into skeletal muscle. The abstract describes Mouse model. The abstract reports: The results show that H(2) promoted 2-[(14)C]-deoxy-d-glucose (2-DG) uptake into C2C12 cells via the translocation of glucose transporter Glut4 through activation of phosphatidylinositol-3-OH kinase…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen-rich saline prevents bone loss in diabetic rats induced by streptozotocin.

This animal study examined Hydrogen-rich saline prevents bone loss in diabetic rats induced by streptozotocin. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results indicate that the systemic delivery of hydrogen saline water, which is safe and well tolerated, preserves bone volume and decreases fracture risks…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen-rich saline attenuates vascular smooth muscle cell proliferation and neointimal hyperplasia by inhibiting reactive oxygen species production and inactivating the Ras-ERK1/2-MEK1/2 and Akt pathways.

This animal study examined Hydrogen-rich saline attenuates vascular smooth muscle cell proliferation and neointimal hyperplasia by inhibiting reactive oxygen species production and inactivating the Ras-ERK1/2-MEK1/2 and Akt pathways. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These results showed that hydrogen-rich saline was able to attenuate FBS-induced VSMC proliferation and neointimal hyperplasia by inhibiting ROS production and inactivating the Ras-ERK1/2-MEK1/2…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Protective effects of hydrogen gas inhalation on radiation-induced bone marrow damage in cancer patients: a retrospective observational study.

This study protocol examined Protective effects of hydrogen gas inhalation on radiation-induced bone marrow damage in cancer patients: a retrospective observational study. The abstract describes Planned or registered research population; sample size 7; hydrogen delivered as hydrogen inhalation; reported duration 30 minutes. The abstract reports: The results obtained demonstrated that H gas inhalation therapy alleviated IMRT-induced bone marrow damage without compromising the anti-tumor effects of IMRT. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Molecular hydrogen therapy in musculoskeletal conditions: An evidence-based review and critical analysis.

This narrative review examined Molecular hydrogen therapy in musculoskeletal conditions: An evidence-based review and critical analysis. The abstract describes Published literature review; hydrogen delivered as hydrogen water. The abstract reports: Preclinical models consistently showed reductions in reactive oxygen species, inflammatory cytokines, and improved cell viability. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen-Rich Saline Attenuates Chronic Allodynia after Bone Fractures via Reducing Spinal CXCL1/CXCR2-Mediated Iron Accumulation in Mice.

This animal study examined Hydrogen-Rich Saline Attenuates Chronic Allodynia after Bone Fractures via Reducing Spinal CXCL1/CXCR2-Mediated Iron Accumulation in Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These findings identify that hydrogen-rich saline confers protection against fracture-caused chronic allodynia via spinal down-modulation of CXCL1-dependent TfR1-mediated iron accumulation in mice. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Effect of H 2 treatment in a mouse model of rheumatoid arthritis‐associated interstitial lung disease

This uncontrolled human study examined Effect of H 2 treatment in a mouse model of rheumatoid arthritis‐associated interstitial lung disease. The abstract describes Human participants. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Molecular Hydrogen Prevents Osteoclast Activation in a Glucocorticoid-Induced Osteoporosis Zebrafish Scale Model.

This animal study examined Molecular Hydrogen Prevents Osteoclast Activation in a Glucocorticoid-Induced Osteoporosis Zebrafish Scale Model. The abstract describes Zebrafish model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen (H) Alleviates Osteoarthritis by Inhibiting Apoptosis and Inflammation via the JNK Signaling Pathway.

This animal study examined Hydrogen (H) Alleviates Osteoarthritis by Inhibiting Apoptosis and Inflammation via the JNK Signaling Pathway. The abstract describes Mouse model. The abstract reports: We uncovered that hydrogen (H) could alleviate apoptosis response and ECM degradation in human chondrocytes via inhibiting the activation of the JNK signaling pathway.…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen-rich saline attenuates ischemia-reperfusion injury in skeletal muscle.

This animal study examined Hydrogen-rich saline attenuates ischemia-reperfusion injury in skeletal muscle. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS seems to be effective in attenuating IR injury in skeletal muscle via its antioxidant, anti-apoptosis, and anti-autophagy effect. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study.

This randomized controlled trial examined Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study. The abstract describes Human participants; hydrogen delivered as injected or infused hydrogen; reported duration 5 days. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an open-label pilot study.

This uncontrolled human study examined Consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an open-label pilot study. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: The results suggest that the hydroxyl radical scavenger H2 effectively reduces oxidative stress in patients with this condition. The symptoms of RA were significantly…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Molecular hydrogen: new antioxidant and anti-inflammatory therapy for rheumatoid arthritis and related diseases.

This uncontrolled human study examined Molecular hydrogen: new antioxidant and anti-inflammatory therapy for rheumatoid arthritis and related diseases. The abstract describes Human participants. The abstract reports: It is also associated with an increased risk of atherosclerosis, which can result in cardiovascular disease and mortality. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: A report of three cases.

This uncontrolled human study examined Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: A report of three cases. The abstract describes Human participants; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More