Hydrogen gas protects against ovariectomy-induced osteoporosis by inhibiting NF-κB activation.

This animal study examined Hydrogen gas protects against ovariectomy-induced osteoporosis by inhibiting NF-κB activation. The abstract describes Mouse model. The abstract reports: H2 markedly inhibited RANKL-induced activation, nuclear translocation, and transcriptional activity of NF-κB (P  These results demonstrated that H2 could be an effective therapeutic agent…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Preventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet.

This animal study examined Preventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Obese rats, induced by a high-fat diet, showed a higher gingival level of 8-hydroxydeoxyguanosine and a lower level of alveolar bone density compared to…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress.

This animal study examined Molecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress. The abstract describes Mouse model. The abstract reports: Rheumatoid arthritis (RA) is a chronic inflammatory disease which results in progressive destruction of the joint. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo.

This animal study examined Hydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results showed that the number of senescence-associated β-galactosidase (SA-β-Gal) positive cells was reduced in BMSCs from rats treated with HRS. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Therapy in Rheumatoid Arthritis: A Case Report on the Amelioration of Methotrexate-induced Myelosuppression and Immune Modulation

This case report or case series examined Molecular Hydrogen Therapy in Rheumatoid Arthritis: A Case Report on the Amelioration of Methotrexate-induced Myelosuppression and Immune Modulation. The abstract describes Human participants. The abstract reports: This is the first case report to highlight severe MTX-induced myelosuppression in an RA patient and to demonstrate the potential of molecular hydrogen therapy…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen suppresses activated Wnt/β-catenin signaling.

This animal study examined Molecular hydrogen suppresses activated Wnt/β-catenin signaling. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: We found that H2 suppresses activated Wnt/β-catenin signaling by promoting phosphorylation and degradation οf β-catenin. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective Effects of Hydrogen-Rich Water Against Cartilage Damage in a Rat Model of Osteoarthritis by Inhibiting Oxidative Stress, Matrix Catabolism, and Apoptosis

This animal study examined Protective Effects of Hydrogen-Rich Water Against Cartilage Damage in a Rat Model of Osteoarthritis by Inhibiting Oxidative Stress, Matrix Catabolism, and Apoptosis. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 30 min. The abstract reports: RESULTS The antioxidant effects of HW suppressed oxidative damage, which may have aided the inhibition of ECM-degrading enzymes (MMP3, MMP13, ADAMT4, and ADAMT5), the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Treatment of hydrogen molecule abates oxidative stress and alleviates bone loss induced by modeled microgravity in rats.

This animal study examined Treatment of hydrogen molecule abates oxidative stress and alleviates bone loss induced by modeled microgravity in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 6 weeks. The abstract reports: Treatment with molecular hydrogen alleviates microgravity-induced bone loss in rats. Molecular hydrogen could thus be envisaged as a nutritional countermeasure for spaceflight but remains…. This is an automated editorial draft based on the abstract and requires source review before publication.

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