Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This narrative review examined the present review aims to provide a consistent summary of the findings of the last twenty years on the use of molecular hydrogen in major respiratory diseases, including allergies, asthma, COPD, pulmonary fibrosis, lung injury of various origins,…
Read ArticleIn the present study, the researchers found that oral gavage with hydrogen-water increased the survival rate and body weight of mice exposed to total abdominal irradiation (TAI); oral…
Read ArticleIn mice, further, the level of interleukin (IL)-1β, tumor necrosis factor (TNF)-α and IL-12p70 in ERW group decreased whereas those of IL-10 increased. These preclinical findings add evidence…
Read ArticleIn a laboratory model, as a result, H₂ protected the cultured cells against the cytotoxic effects induced by tert-butyl hydroperoxide; H₂ suppressed cellular fatty acid peroxidation and cell…
Read ArticleThe results of the H&E, and Nissl staining indicated that the CLP mice had a significant brain injury, which was characterized by aggravated pathological damage and was alleviated…
Read ArticleIn an animal model, hydrogen-rich saline treatment significantly reduced the level of degraded myelin basic protein, decreased the expression of ionized calcium-binding adapter molecule 1, Iba1, a microglial…
Read ArticleIn male C57BL/6 mice, treatment with HS reduced the levels of these markers and alleviated morphological defects in the mitochondria following injury. These preclinical findings add evidence supporting…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Further, the article reveals ex vivo hydrogen application in liver protection. The reviewed evidence adds support for molecular hydrogen's therapeutic…
Read ArticleIn rats, inhalation of hydrogen gas at 2% concentration for 1 h significantly reduced the serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities, the expression of cytokines,…
Read ArticleIn rats, compared to lactated Ringer's solution, hydrogen-rich solution, or hyperoxygenated solution groups, serum AST and alanine aminotransferase levels and IL-6, tumor necrosis factor-α, and malondialdehyde expression in…
Read ArticleIn rats, saturated hydrogen saline also decreased phosphorylated extracellular signal-regulated kinase (p-ERK), phosphorylated Jun kinase (p-JNK), nuclear factor-kappa B (NF-kappaB), and second mitochondria-derived activator of caspase (Smac) levels,…
Read ArticleIn mice, the HW group showed a smaller decrease in hepatic cholesterol; however, stronger antioxidative effects in serum and lower peroxisome proliferator-activated receptor-α expression in the liver were…
Read ArticleIn mice, HRW attenuated malondialdehyde level, restored glutathione depletion and increased superoxide dismutase, glutathione peroxidase and catalase activities in the liver. These preclinical findings add evidence supporting molecular…
Read ArticleIn the present study, the researchers found that HRCC treatment improved methionine-and-choline-deficient diet (MCD)-induced hepatic steatosis, increased aspartate aminotransferase and alanine aminotransferase levels, and elevated hepatic inflammatory factor…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Despite compelling preclinical evidence demonstrating efficacy in myocardial injury, neurodegeneration, and systemic inflammation, significant translational barriers remain including delivery optimization,…
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