Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In male Sprague-Dawley rats, hydrogen-rich water treatment improved hemodynamics and reversed right ventricular hypertrophy. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn conclusion, consumption of HW is a promising strategy to alleviate renal injury as a supplement for anti-hypertensive therapy. These preclinical findings add evidence about the molecular-hydrogen effects,…
Read ArticleIn mice, intrathecal delivery of recombinant CXCL1 induces acute allodynia and spinal iron overload, which is reversed by hydrogen-rich water. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn an animal model, an in vitro study performed on RAW264.7 murine cells showed that H₂ treatment prevents RANKL-associated osteoclastogenesis, inhibiting the inactivation of NF-kB, mitogen-activated protein kinase…
Read ArticleIn a laboratory model, treatment with hydrogen reduced LPS/IFNγ-induced NO release, which was associated with a diminished induction of inducible isoform of nitric oxide synthase (iNOS). The authors…
Read ArticleIn rats, drinking hydrogen-rich water suppressed body weight gain, lowered gingival level of 8-hydroxydeoxyguanosine, and reduced alveolar bone resorption in rats on a high-fat diet. These preclinical findings…
Read ArticleIn rats, treatment with HW abated oxidative stress and suppressed IL-6 and TNF-α mRNA expressions in femur of ovariectomized rats; treatment with HW increased femur endothelial NOS activity…
Read ArticleIn rats, hW showed a protective effect against the progression of OA in an animal model, which may have been mediated by its anti-oxidant and anti-apoptotic activities. These…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleIn mice, hydrogen-rich water improved brain energy metabolism disorders and intestinal flora imbalances and reduced inflammatory reactions. These results are preclinical and suggest molecular hydrogen's therapeutic potential in…
Read ArticleIn a laboratory model, taken together, the findings suggest that HRW may have potential therapeutic value to inhibit Aβ-induced neurotoxicity. These findings from a laboratory model add evidence…
Read ArticleThe researchers found that hydrogen-rich water significantly improved cognitive behaviour in female transgenic AD mice without affecting Aβ clearance, and reversed the brain oestrogen level, ERβ, and brain-derived…
Read ArticleIn mice, biochemical indicators showed that pro-inflammatory factors IL-6 ( p < 0.01), IL-1β ( p < 0.001), and TNF-α ( p < 0.01), decreased. The anti-inflammatory factor…
Read ArticleIn 40 participants, a significant treatment vs. time interaction was found for telomere length (P = 0.049), with the length increased after HRW intervention (from 0.99 ± 0.15…
Read ArticleIn mice, H₂ improved aging-related biomarkers, ie, total antioxidant capacity, advanced glycation end products, tumor necrosis factor-α, free fatty acids, and alanine aminotransferase in plasma. These preclinical findings…
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