Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, kEY FINDINGS: H2W consumption significantly attenuated plaque formation and enhanced plaque stability in ApoE-/- mice, accompanied by altered gut microbiota structure and short-chain fatty acid profiles. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleIn The purpose of this study is to evaluate the effect of hydrogen on unstable angina in vitro and in vivo, serum analysis showed that hydrogen-rich water addition…
Read ArticleIn mice, mHW intake improved cardiac hypertrophy, shortened the width of cardiomyocytes, dilated the capillaries and arterioles, activated myocardial eNOS-Ser-1177 phosphorylation, and restored left ventricular function in DIO…
Read ArticleIn rats, compared with the ischemic period, the ischemia-reperfusion phase showed significantly increased SOD activity and significantly decreased MDA content in the hydrogen-rich water group, while SOD activity…
Read ArticleIn Wistar rats, 25 proteins that are involved in hydrogen-water reducing MIRI were selected by high-throughput GSR-CAA-67. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The authors highlighted early evidence of cytoprotective, antioxidant, and anti-inflammatory effects. The reviewed evidence adds support for molecular hydrogen's therapeutic…
Read ArticleIn male Wistar rats, hW intake may prevent lipid deposition in the rat aorta induced by periodontitis by decreasing serum ox-LDL levels and aortic oxidative stress. These preclinical…
Read ArticleIn male Wistar rats, the apoptosis rate was significantly decreased in the hydrogen-rich water group, as well. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleIn rats, finally, as a pivotal transcription factor in reactive oxygen species (ROS)-apoptosis signaling pathway, the expression and phosphorylation of p53 were significantly reduced by H₂ treatment in…
Read ArticleIn Human umbilical vein endothelial cells (HUVECs) were incubated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) for various time periods in normal or hydrogen-rich medium, however, HUVECs incubated in hydrogen-rich medium did…
Read ArticleIn Sprague Dawley rats, hRS treatment significantly increased the viability of myocardial cells, reduced the rate of myocardial cellular apoptosis and the release of MDA and LDH compared…
Read ArticleT cell proliferation was significantly inhibited in the presence of hydrogen in vitro, accompanied by less production of interleukin-2 and interferon-γ, hydrogen treatment was also associated with increased…
Read ArticleIn mice, atherosclerotic lesions were significantly reduced by ad libitum drinking of H(2)-water (p=0.0069) as judged by Oil-Red-O staining series of sections of aorta. These preclinical findings add…
Read ArticleIn mice, the numbers of endothelial cells in the atheroma expressing the senescence factors p16INK4a and p21 decreased in HFD-fed mice given HW compared with HFD-fed mice given…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. This article highlights the dual role of diet in generating molecular hydrogen ( H₂ ) in the gut, and H₂…
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