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In 42 patients, the intracellular IL-2 and IFN-gamma levels in the Th1/Tc1 cells significantly (P < 0.05) increased and the intracellular IL-4, IL-6 and IL-10 levels in the Th2/Tc2 cells decreased. These findings add human evidence supporting molecular hydrogen's therapeutic potential to…
Read ArticleIn male Sprague Dawley rats, saturated hydrogen saline can maintain good mechanical properties and reduce dilatation of the aorta by increasing residual strain and reducing the remodeling of…
Read ArticleIn guinea pigs, both the number and the cytokine secretion of CD4(+) CD25(+) Foxp3(+) Treg cells are decreased in AR group, hydrogen-rich saline may inhibit inflammatory response and…
Read ArticleIn Sprague-Dawley rats, hydrogen-rich saline can decrease the levels of inflammatory mediators and reduce the pathological damage of pancreas through the inhibition of oxidative stress. These preclinical findings…
Read ArticleIn rats, the administration of HRS resulted in a significant decrease in the brain injury, together with lower production of IL-1β, TNF-α, 8-OHdG and MDA as well as…
Read ArticleThis publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
Read ArticleIn BALB/c mice, forty percent of aGVHD mice with physiologic saline treatment survived to the 18 th day after BMT, and 90% of the mice with hydrogen-rich saline…
Read ArticleIn male Sprague-Dawley rats, tumor necrosis factor-alpha (TNF-α) levels, malondialdehyde (MDA) concentrations, nuclear factor kappa B (NF-κB) p65 expression, and apoptosis index (AI) in I+HS group were significantly…
Read ArticleIn Sprague-Dawley rats, compared with group C and group S, HRS and EDHB injection significantly increased the number of autophagosomes and autolysosomes in the spinal cord at 14…
Read ArticleIn guinea pigs, the frequencies of sneezing and scratching, as well as the levels of IgE, IL-4, and IL-13, in the serum were higher in the AR group…
Read ArticleIn mice, kEY FINDING: The leakage and non-perfusion areas of retinal blood vessels were not alleviated in the HRS treatment group. These preclinical findings add evidence supporting molecular…
Read ArticleThe results of the present study demonstrate that, after experimental spinal cord injury in rats, hydrogen-rich water treatment significantly decreased inflammation as evidenced by decreased IL-6 and TNF-α…
Read ArticleIn rabbits, here, the researchers found that I/R-challenged rabbits exhibited significant spinal cord injury characterized by the decreased numbers of normal motor neurons and hind-limb motor dysfunction, which…
Read ArticleIn rats, hydrogen-rich medium attenuated the intracellular production of ROS (especially HO•), astrogliosis, and the secretion of proinflammatory cytokines in astrocytes 12 h after H₂O₂-induced injury. These preclinical…
Read ArticleIn mice, figure 1 Administration of hydrogen‐rich saline intraperitoneally from the 20th day after transplantation protects mice from cGVHD ( n = 30, P < 0.05). These preclinical…
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