Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In 3 patients, iL-17, whose concentration was high in Case 1, was reduced following H₂ treatment, and TNFα also decreased in Case 1. These findings add human evidence supporting molecular hydrogen's therapeutic potential for rheumatoid arthritis.
Read ArticleThis narrative review examined the available molecular-hydrogen literature. By drinking 500 ml of the high H₂ water daily for four weeks, oxidative stress was effectively reduced and the…
Read ArticleIn a laboratory model, H₂ decreased the levels of the nitrated proteins, and suppressed chondrocyte death. The authors concluded that moreover, novel pharmacological strategies aimed at selective removal…
Read ArticleIn mice, the amount of trabecular bone and bone mineral density of OVX mice that inhaled H₂ were more than 40% higher, whereas the levels of serum proinflammatory…
Read ArticleRecently, it has been demonstrated that hydrogen gas, known as a novel antioxidant, can exert therapeutic anti-inflammatory effect in many diseases. This source-grounded publication contributes evidence relevant to…
Read ArticleIn a laboratory model, treatment with hydrogen reduced LPS/IFNγ-induced NO release, which was associated with a diminished induction of inducible isoform of nitric oxide synthase (iNOS). The authors…
Read ArticleIn mice, based on the authors' result, H₂ enriched medium can increase super oxide dismutase (SOD) level following H₂O₂ treatment and decrease 8-hydroxy-2'-deoxyguanosine (8-OHdG) level. These preclinical findings…
Read ArticleIn Methotrexate (MTX) remains a cornerstone of RA treatment, offering significant therapeutic benefits, this is the first case report to highlight severe MTX-induced myelosuppression in an RA patient…
Read ArticleIn rats, treatment with HW abated oxidative stress and suppressed IL-6 and TNF-α mRNA expressions in femur of ovariectomized rats; treatment with HW increased femur endothelial NOS activity…
Read ArticleIn mice, H₂ treatment significantly attenuated ROS production in AβO-stimulated primary mouse astrocytes, showing a 1.2-fold reduction compared with vehicle ( p < 0.05; Figure 2 A). These…
Read ArticleIn contrast, HRW treatment improved these emotional disorders in 3×Tg-AD mice, with an increased frequency of grid crossings and rearing and a decreased frequency of defecation ( P…
Read ArticleThe researchers found that hydrogen-rich water significantly improved cognitive behaviour in female transgenic AD mice without affecting Aβ clearance, and reversed the brain oestrogen level, ERβ, and brain-derived…
Read ArticleIn mice, biochemical indicators showed that pro-inflammatory factors IL-6 ( p < 0.01), IL-1β ( p < 0.001), and TNF-α ( p < 0.01), decreased. The anti-inflammatory factor…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
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