Hydrogen-rich saline attenuates neuronal ischemia–reperfusion injury by protecting mitochondrial function in rats.
This animal study examined Hydrogen-rich saline attenuates neuronal ischemia–reperfusion injury by protecting mitochondrial function in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen, a popular antioxidant gas, can selectively reduce cytotoxic oxygen radicals and has been found to protect against ischemia-reperfusion (I/R) injury of multiple organs. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA double-blinded, randomized controlled clinical trial of hydrogen inhalation therapy for idiopathic sudden sensorineural hearing loss.
This study protocol examined A double-blinded, randomized controlled clinical trial of hydrogen inhalation therapy for idiopathic sudden sensorineural hearing loss. The abstract describes Planned or registered research population; hydrogen delivered as hydrogen inhalation. The abstract reports: This is the first study to investigate the efficacy of H for the treatment of ISSNHL in humans. The results suggest that H therapy…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen alleviated cognitive impairment and blood‒brain barrier damage in sepsis-associated encephalopathy by regulating ABC efflux transporters in a PPARα-dependent manner.
This animal study examined Hydrogen alleviated cognitive impairment and blood‒brain barrier damage in sepsis-associated encephalopathy by regulating ABC efflux transporters in a PPARα-dependent manner. The abstract describes Mouse model. The abstract reports: Finally, we found that H improved survival rates and brain dysfunction and decreased inflammatory cytokines. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates blood-brain barrier impairment and cognitive dysfunction of septic mice in an Nrf2-dependent pathway
This animal study examined Hydrogen gas alleviates blood-brain barrier impairment and cognitive dysfunction of septic mice in an Nrf2-dependent pathway. The abstract describes Mouse model. The abstract reports: We found that H can improve survival in septic mice, decrease escape latency and platform crossing times, decrease pro-inflammatory cytokines and oxidative product levels…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation therapy may ameliorate amyotrophic lateral sclerosis.
This uncontrolled human study examined Hydrogen inhalation therapy may ameliorate amyotrophic lateral sclerosis. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Amyotrophic lateral sclerosis (ALS) is a motor neuron disease, a neurodegenerative disorder characterized by sporadic and progressive degenerative loss of cell bodies of both…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water improves neurological functional recovery in experimental autoimmune encephalomyelitis mice.
This animal study examined Hydrogen-rich water improves neurological functional recovery in experimental autoimmune encephalomyelitis mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: We found that prophylactic administration of both 0.36mM and 0.89mM HRW was able to delay EAE onset and reduce maximum clinical scores. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConflicting findings on the effectiveness of hydrogen therapy for ameliorating vascular leakage in a 5-day post hypoxic-ischemic survival piglet model.
This animal study examined Conflicting findings on the effectiveness of hydrogen therapy for ameliorating vascular leakage in a 5-day post hypoxic-ischemic survival piglet model. The abstract describes Porcine model. The abstract reports: The ratio of albumin stained to unstained areas was analyzed and found to be lower in the H group than in the other groups,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreBrain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report.
This case report or case series examined Brain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report. The abstract describes hydrogen delivered as hydrogen inhalation; reported duration 28 months. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of perioperative hydrogen inhalation on brain edema and prognosis in patients with glioma: a single-center, randomized controlled study.
This randomized controlled trial examined Effects of perioperative hydrogen inhalation on brain edema and prognosis in patients with glioma: a single-center, randomized controlled study. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: The volume of brain edema before discharge was significantly lower in the H group ( . This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer’s Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation—Fantasy or Reality?
This in vitro or cellular study examined Molecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer’s Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation—Fantasy or Reality?. The abstract describes Cell culture / in vitro model. The abstract reports: Recent studies in animal models of focal or global cerebral ischemia and cerebral ischemia in humans suggest that hydrogen has pleiotropic neuroprotective properties. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTherapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer’s disease: targeting oxidative stress, inflammation, and the gut-brain axis.
This animal study examined Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer’s disease: targeting oxidative stress, inflammation, and the gut-brain axis. The abstract describes Zebrafish model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
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