[Effect of hydrogen-rich water on the CD34 expression in lesion boundary brain tissue of rats with traumatic brain injury].

This animal study examined [Effect of hydrogen-rich water on the CD34 expression in lesion boundary brain tissue of rats with traumatic brain injury]. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: NSS scores in TBI and TBI+HW groups showed a decreased tendency with time prolongation after TBI, which showed more significant in TBI+HW group, NSS…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Effects of hydrogen-rich water on the expression of aquaporin 1 in the cerebral cortex of rat with traumatic brain injury].

This animal study examined [Effects of hydrogen-rich water on the expression of aquaporin 1 in the cerebral cortex of rat with traumatic brain injury]. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 5 days. The abstract reports: The up-regulation of AQP1 mRNA and protein in rats' cerebral cortex after TBI perhaps participates in edema formation which might be involved in the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Hydrogen-rich saline attenuates hyperalgesia and reduces cytokines in rats with post-herpetic neuralgia via activating autophagy].

This animal study examined [Hydrogen-rich saline attenuates hyperalgesia and reduces cytokines in rats with post-herpetic neuralgia via activating autophagy]. The abstract describes Rat model; sample size 20; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline attenuated PWT and inhibited the release of cytokines TNF-α,IL-1β,IL-6 in rats with PHN via activating autophagy. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Effect of hydrogen-rich water on the chondriosome damage and cytokines in brain tissue of rats with traumatic brain injury].

This animal study examined [Effect of hydrogen-rich water on the chondriosome damage and cytokines in brain tissue of rats with traumatic brain injury]. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: NSS scores in TBI and TBI+HW groups showed a decreased tendency with time prolongation after TBI. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Effects of hydrogen rich water on the expression of Nrf 2 and the oxidative stress in rats with traumatic brain injury].

This animal study examined [Effects of hydrogen rich water on the expression of Nrf 2 and the oxidative stress in rats with traumatic brain injury]. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 5 days. The abstract reports: Compared with TBI group, the parameters in HW group were improved, and they were similar as sham operation group. (3) RT-qPCR: no significant difference…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Role of Gaseous Molecules in Traumatic Brain Injury: An Updated Review.

This narrative review examined The Role of Gaseous Molecules in Traumatic Brain Injury: An Updated Review. The abstract describes Published literature review. The abstract reports: Biological gaseous molecules including nitric oxide (NO), carbon monoxide (CO), hydrogen sulfide (HS), and molecular hydrogen (H) have been found to play critical roles…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Nuclear factor-κB/Bcl-XL pathway is involved in the protective effect of hydrogen-rich saline on the brain following experimental subarachnoid hemorrhage in rabbits.

This animal study examined Nuclear factor-κB/Bcl-XL pathway is involved in the protective effect of hydrogen-rich saline on the brain following experimental subarachnoid hemorrhage in rabbits. The abstract describes Rabbit model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Correspondingly, TUNEL staining demonstrated obvious neuronal apoptosis following SAH. This is an automated editorial draft based on the abstract and requires source review before publication.

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Lactulose ameliorates cerebral ischemia-reperfusion injury in rats by inducing hydrogen by activating Nrf2 expression.

This animal study examined Lactulose ameliorates cerebral ischemia-reperfusion injury in rats by inducing hydrogen by activating Nrf2 expression. The abstract describes Rat model. The abstract reports: Behaviorally, rats in the lactulose administration group won higher neurological scores and showed shorter escape latency time in the Morris test. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Inhalation is Superior to Mild Hypothermia for Improving Neurological Outcome and Survival in a Cardiac Arrest Model of Spontaneously Hypertensive Rat.

This animal study examined Hydrogen Inhalation is Superior to Mild Hypothermia for Improving Neurological Outcome and Survival in a Cardiac Arrest Model of Spontaneously Hypertensive Rat. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen inhaling was superior to mild hypothermia for improving neurological outcome and survival in cardiac arrest and resuscitation model of systemic hypertension rats. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of hydrogen-rich saline on rats with acute carbon monoxide poisoning.

This animal study examined Effects of hydrogen-rich saline on rats with acute carbon monoxide poisoning. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: H(2)-rich saline may effectively protect the brain from injury after acute CO poisoning. The mechanism of this protection may be related to lessening oxidative…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages.

This animal study examined Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation; reported duration 42 days. The abstract reports: Hydrogen inhalation (75%) ameliorated SCI in vivo and attenuated neuronal mechanical injuries in vitro, and its protective effect on spinal cord neurons was exerted…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline mediates neuroprotection through the regulation of endoplasmic reticulum stress and autophagy under hypoxia-ischemia neonatal brain injury in mice.

This animal study examined Hydrogen-rich saline mediates neuroprotection through the regulation of endoplasmic reticulum stress and autophagy under hypoxia-ischemia neonatal brain injury in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results showed that HS treatment significantly improved brain edema and decreased infarct volume. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β Signaling Pathway in Rats.

This animal study examined Hydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β Signaling Pathway in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The PI3K/Akt/GSK3β signaling pathway plays an important role in the mechanism of CPB-induced brain injury. HRS can reduce CPB-induced brain injury and inhibit CMEC…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis.

This animal study examined Inhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis. The abstract describes Mouse model; reported duration 60 min. The abstract reports: CLP mice showed obvious brain injury characterized by aggravated pathological damage, BBB disruption and brain edema at 24h after CLP operation, which was markedly…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen exerts neuroprotective effects on OGD/R damaged neurons in rat hippocampal by protecting mitochondrial function via regulating mitophagy mediated by PINK1/Parkin signaling pathway.

This uncontrolled human study examined Hydrogen exerts neuroprotective effects on OGD/R damaged neurons in rat hippocampal by protecting mitochondrial function via regulating mitophagy mediated by PINK1/Parkin signaling pathway. The abstract describes Human participants. The abstract reports: The results of MTT indicated that H2 and RAP could increase cell viability after OGD/R treatment, while 3-MA further aggravated injury and inhibited the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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