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Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, hydrogen treatment upregulated SIRT1 expression and promoted PINK1/Parkin-mediated mitophagy, leading to reduced phosphorylation of STING, decreased levels of pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α), and suppressed neuronal apoptosis in the hippocampal CA1 region. These preclinical findings add evidence supporting molecular…
Read ArticleIn Animal models of SAE were generated by cecal ligation and puncture, and the SAE model was established by in vitro LPS stimulation, finally, hydrogen treatment improved the…
Read ArticleIn mice, molecular hydrogen treatment improved gut microbiota dysbiosis and partially amended metabolic disorder after SAE. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleIn mice, inhalation of 67% H₂ improved the 7-day survival rates and recognition memory function of septic mice, alleviated brain antioxidant enzyme activity (SOD and CAT), and reduced…
Read ArticleIn rats, the study has systematically elucidated the molecular mechanism of HRW against ionizing radiation, which can be mediated by modulating targets, pathways and metabolite levels. These preclinical…
Read ArticleIn mice, following treatment with oxaliplatin, the expression of inflammatory cytokines TNF-α and IL-6 was significantly increased (P<0.05, H₂O + OXA vs H₂O + Saline; P<0.05, HW +…
Read ArticleThe researchers found that hydrogen-rich saline significantly elevated the mechanical thresholds of neuropathic pain compared to vehicle (physiologic saline) control in CCI rats (p 0.05), an ATP receptor.…
Read ArticleIn rats, compared with N group, the percentage of time spent in the target quadrant and the frequency of crossing the platform of rats in T group were…
Read ArticleIn Wistar rats, after HS administration, all these parameters were considerably improved, and the characteristics of hSCI testes were similar to those of normal control testes. These preclinical…
Read ArticleIn rats, compared with hydrogen-rich saline treatment, hydrogen inhalation significantly reduced blood glucose levels in diabetic rats in the 4th and 8th weeks. These preclinical findings add evidence…
Read ArticleIn rats, HRW treatment decreased DAPI/PI/β‐PDGFR and β‐PDGFR/ROS‐positive cells while increasing the β‐PDGFR/SOD‐positive cells, indicating that HRW attenuated HI‐induced oxidative stress injury in pericytes (Figure 1B–D ). These…
Read ArticleIn Both groups received standard treatment plus 4 daily 1-h interventions for 14 consecutive days, although it is generally safe and feasible, its potential effects on myocardial, liver…
Read ArticleThis narrative review examined metabolomic and phosphoproteomic analyses were utilized to explore the therapeutic mechanism of H₂. The WB and IF results revealed that DGKζ expression increased in…
Read ArticleThe researchers showed a possible hydrogen-driven upregulation of neurotransmitters involved in appetite stimulation leading to hunger suppression and weight loss. This source-grounded publication contributes evidence relevant to molecular…
Read ArticleIn In vitro, BMSCs were cultured in a normal medium and a hydrogen-rich medium to study the effect of hydrogen on the proliferation and migration of BMSCs, hydrogen…
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