[The interventional effects of saturated hydrogen saline on lung injury in rats with cecal ligation and puncture operation].

This animal study examined [The interventional effects of saturated hydrogen saline on lung injury in rats with cecal ligation and puncture operation]. The abstract describes Rat model; sample size 6; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These results indicate that hydrogen-rich saline peritoneal injection improves the lung injury induced by CLP operation. The therapeutic effects of hydrogen-rich saline may be…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Effect of hydrogen inhalation on p38 MAPK activation in rats with lipopolysaccharide- induced acute lung injury].

This animal study examined [Effect of hydrogen inhalation on p38 MAPK activation in rats with lipopolysaccharide- induced acute lung injury]. The abstract describes Rat model; sample size 8; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Hydrogen inhalation can decrease the expression of TNF-α in the lung tissue and serum, and this effect may be related with reduced p38 MAPK…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Protective effect of hydrogen on the lung of sanitation workers exposed to haze].

This randomized controlled trial examined [Protective effect of hydrogen on the lung of sanitation workers exposed to haze]. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 30 days. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline ameliorated LPS-induced acute lung injury via autophagy inhibition through the ROS/AMPK/mTOR pathway in mice.

This animal study examined Hydrogen-rich saline ameliorated LPS-induced acute lung injury via autophagy inhibition through the ROS/AMPK/mTOR pathway in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results showed that HRS ameliorated lipopolysaccharide-induced ALI in mice by inhibiting autophagy over-activation through ROS/AMPK/mTOR pathway. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hyperbaric Oxygen Combined With Hydrogen-rich Saline Protect Against Acute Lung Injury Induced by Lipopolysaccharide in Rat Model

This animal study examined Hyperbaric Oxygen Combined With Hydrogen-rich Saline Protect Against Acute Lung Injury Induced by Lipopolysaccharide in Rat Model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Results: In the groups treated with HRS and HBO, pulmonary pathological data, wet-dry weight ratio and immflammatory factors in the pulmonary tissues and avelar…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus-activated kinase 2/signal transducer and activator of transcription 3 signaling pathway.

This animal study examined Hydrogen-rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus-activated kinase 2/signal transducer and activator of transcription 3 signaling pathway. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: The HRS treatment resulted in the significant upregulation of malonyl dialdehyde (MDA) and myeloperoxidase (MPO), whilesuperoxide dismutase (SOD) levels were significantly downregulated, compared with…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Effect of hydrogen-rich saline on blood pressure and antioxidant ability of lung tissue in scalded rats following delayed resuscitation].

This animal study examined [Effect of hydrogen-rich saline on blood pressure and antioxidant ability of lung tissue in scalded rats following delayed resuscitation]. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Delayed resuscitation for scalded rats with hydrogen-rich saline is helpful in the recovery of systolic pressure, and it can ameliorate lung tissue injury caused…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen mitigates traumatic brain injury-induced lung injury via NLRP3 inflammasome inhibition.

This animal study examined Molecular hydrogen mitigates traumatic brain injury-induced lung injury via NLRP3 inflammasome inhibition. The abstract describes Mouse model. The abstract reports: 2% H can protect against TBI-induced lung injury by inhibiting NLRP3 inflammasome activation, thereby alleviating inflammation and inhibiting apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen alleviates lung injury after traumatic brain injury: Pyroptosis and apoptosis.

This uncontrolled human study examined Molecular hydrogen alleviates lung injury after traumatic brain injury: Pyroptosis and apoptosis. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: H improves TBI-ALI, and the mechanism may be due to the decrease of both pyroptosis and apoptosis and the alleviation of inflammation. These findings…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas inhalation during ex vivo lung perfusion of donor lungs recovered after cardiac death.

This animal study examined Hydrogen gas inhalation during ex vivo lung perfusion of donor lungs recovered after cardiac death. The abstract describes Animal model; hydrogen delivered as hydrogen inhalation; reported duration 1 hour. The abstract reports: Hydrogen gas inhalation during EVLP improved donation after cardiac death lung function via reduction of inflammation and apoptosis, and this effect persisted after LTx. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas with extracorporeal cardiopulmonary resuscitation improves survival after prolonged cardiac arrest in rats.

This uncontrolled human study examined Hydrogen gas with extracorporeal cardiopulmonary resuscitation improves survival after prolonged cardiac arrest in rats. The abstract describes Human participants. The abstract reports: H therapy improved mortality in highly lethal CA rats rescued by ECPR and helped recover brain electrical activity. The underlying mechanism might be linked…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen‐rich and hyperoxygenate saline inhibits lipopolysaccharide‐induced lung injury through mediating NF‐κB/NLRP3 signaling pathway in C57BL/6 mice

This animal study examined Hydrogen‐rich and hyperoxygenate saline inhibits lipopolysaccharide‐induced lung injury through mediating NF‐κB/NLRP3 signaling pathway in C57BL/6 mice. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. The abstract reports: Hydrogen plays a more important role in the inflammatory and anti-apoptosis mechanisms, while oxygen improves hypoxia of the body, and thus, its molecular mechanism…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen therapy can be used to control tumor progression and alleviate the adverse events of medications in patients with advanced non-small cell lung cancer.

This uncontrolled human study examined Hydrogen therapy can be used to control tumor progression and alleviate the adverse events of medications in patients with advanced non-small cell lung cancer. The abstract describes Human participants; sample size 10; reported duration 5 months. The abstract reports: According to the results of tumor-gene mutations and drug-sensitivity tests, 10, 18, and 10 patients were enrolled into chemotherapy, targeted therapy, and immunotherapy groups…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma.

This animal study examined Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: These findings suggest that hydrogen-rich saline reduces airway inflammation and remodeling in OVA-exposed mice by inhibiting NF-κB. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective Effects of a Hydrogen-Rich Preservation Solution in a Canine Lung Transplantation Model.

This animal study examined Protective Effects of a Hydrogen-Rich Preservation Solution in a Canine Lung Transplantation Model. The abstract describes Canine model; reported duration 4 hours. The abstract reports: Our results demonstrated that the H-rich preservation solution attenuated ischemia-reperfusion injury in a canine left LTx model. This is an automated editorial draft based on the abstract and requires source review before publication.

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